Review
Biochemistry & Molecular Biology
Yun-Yun Wei, Shuang Liang, Xue-Ming Zhu, Xiao-Hong Liu, Fu-Cheng Lin
Summary: This article summarizes the latest research on effector identification, classification, function, secretion, and control mechanism in Magnaporthe oryzae, the causal agent of recalcitrant rice blast disease. It also discusses future directions and challenges for research on effectors in M. oryzae.
Review
Chemistry, Physical
Bing Jiang, Zhanjun Guo, Minmin Liang
Summary: Single-atom nanozymes (SAzyme) are a hot topic in current nanozyme research due to their high activity, stability, and low cost, which make them great substitutes for natural enzymes. SAzymes also have higher catalytic activities and specificity compared to traditional nanozymes due to their maximized atom utilizations and well-defined geometric and electronic structures. They have been widely applied in various biomedical areas, including anti-tumor therapy, biosensing, antibiosis, and anti-oxidation therapy. In this review, representative examples of SAzymes categorized by their biomedical applications will be discussed, along with future opportunities and challenges they face in their designs and applications.
Review
Chemistry, Physical
Bing Jiang, Zhanjun Guo, Minmin Liang
Summary: Single-atom nanozyme (SAzyme) is a hot topic in current nanozyme research, due to its high activity, stability, and low cost. Compared to traditional nanozymes, SAzyme exhibits higher catalytic activities and specificity. In biomedical areas, SAzyme has been widely applied in anti-tumor therapy, biosensing, antibiosis, and anti-oxidation therapy.
Article
Plant Sciences
Xiao Yin, Qingqing Fu, Boxing Shang, Yunlei Wang, Ruiqi Liu, Tingting Chen, Gaoqing Xiang, Mengru Dou, Guotian Liu, Yan Xu
Summary: This study reports an RxLR effector, RxLR50253, from Plasmopara viticola that interferes with plant immune response, promoting pathogen colonization in tobacco and grapevine leaves. The host target of RxLR50253 was identified as VpBPA1, whose interaction with RxLR50253 was confirmed through multiple assays. Further analysis revealed that VpBPA1 promotes pathogen colonization and decreases H2O2 accumulation. This study uncovers the mechanism by which Plasmopara viticola attenuates plant immunity during pathogen infection.
Review
Medical Laboratory Technology
Xiao-Hua Yu, Wen-Yi Deng, Hong-Tao Jiang, Tao Li, Yi Wang
Summary: Kidney transplantation is an effective treatment for end-stage renal disease but faces limitations due to a shortage of human donor kidneys. Xenotransplantation using pig organs has shown promising results in prolonging survival in non-human primates. With advances in genetic modifications and immunosuppressive regimens, clinical trials for pig kidney transplantation may soon be initiated.
CLINICA CHIMICA ACTA
(2021)
Article
Plant Sciences
Tao Ma, Shuyun Chen, Jiaqi Liu, Peining Fu, Wei Wu, Shiren Song, Yu Gao, Wenxiu Ye, Jiang Lu
Summary: Plasmopara viticola, the causal organism of grapevine downy mildew, secretes a variety of effectors to manipulate host immunity. A study found that the effector PvRXLR111 interacts with the plant transcription factor VvWRKY40 to suppress host immunity, suggesting that VvWRKY40 functions as a negative regulator in plant immunity.
MOLECULAR PLANT PATHOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Ting-Wei Kao, Chin-Chou Huang
Summary: Metabolic syndrome is a challenging disease with increasing incidence and diverse affected populations, requiring thorough investigation. Recent studies have shown differential expression of substances in MetS, as well as the influence of diet and exercise on energy metabolism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Chemistry, Multidisciplinary
Hongtao Ren, Gang Xiang
Summary: This article summarizes the recent progress on ferromagnetism in ReS2, compares the methods to introduce and modulate magnetism in ReS2, presents potential research directions for the future, and emphasizes the importance of a deep understanding of the origin of ferromagnetism for both basic research and practical applications.
Article
Plant Sciences
Ruiqi Liu, Tingting Chen, Xiao Yin, Gaoqing Xiang, Jing Peng, Qingqing Fu, Mengyuan Li, Boxing Shang, Hui Ma, Guotian Liu, Yuejin Wang, Yan Xu
Summary: Pathogens secrete effectors to manipulate host cells, such as Plasmopara viticola's RXLR31154 which interacts with the host protein VpPsbP to enhance colonization. Furthermore, VpPsbP in chloroplasts reduces H2O2 accumulation and activates the O-1(2) signaling pathway, promoting disease.
Article
Plant Sciences
Wei Luo, Bei Wu, Liangjie Tang, Guoyou Li, Hulan Chen, Xuemei Yin
Summary: The genus Cirsium has been used in traditional Chinese medicine for centuries, with believed efficacies of cooling blood and stopping bleeding. Recent studies have shown various pharmacological effects and isolated chemical constituents from Cirsium plants. They are widely used in treating various conditions, but further research is needed for quality control systems and in-depth study of their mechanisms of action.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Environmental Sciences
Jennifer Murrins Misiukas, Sarah Carter, Martin Herold
Summary: Forest monitoring involves recurrent measurement of forest parameters to track changes over time. Recent research on tropical forest monitoring indicates a concentration of studies in countries with strong monitoring capabilities, facing challenges from biophysical and anthropogenic influences. Future research should target countries with lower capacities and higher needs for improved forest monitoring and conservation.
Article
Business
Dennis Herhausen, Stefan F. Bernritter, Eric W. T. Ngai, Ajay Kumar, Dursun Delen
Summary: Decision-making in marketing has undergone significant changes in the past decade, with increasing attention being paid to the applications of machine learning. While machine learning brings intelligence and efficiency to marketing, it also presents challenges. This article provides an overview of machine learning applications in marketing and proposes future research directions.
JOURNAL OF BUSINESS RESEARCH
(2024)
Article
Chemistry, Applied
Yaohua Zhu, Shengli Cao, Shuijun Zhang, Jing Liu
Summary: Fluorescent probes covalently linked to galactose-based scaffolds can specifically target hepatocytes through the asialoglycoprotein receptor, monitoring metabolic activity and diagnosing liver cancer cells. They have high sensitivity, selectivity, excellent spatial-temporal resolution, and non-invasiveness for detecting and imaging reactive species in liver tissues and in vivo.
Review
Chemistry, Physical
Gaosong Yi, Eloy Macha, Jeff Van Dyke, Rafael Ed Macha, Tim McKay, Michael L. Free
Summary: Molybdenum is a key alloy element in the metallurgical industry due to its high temperature stability. Molybdenite, the major mineral reserve for molybdenum found in porphyry copper deposits, can be separated from copper sulfide mineral using froth flotation. Various factors such as mineralogy, microstructure, surface wettability, and zeta potential can affect the floatability of molybdenite, with organic and inorganic depressants and surface pre-treatment methods applied to improve recovery rates. Measurements of electrochemical potential using different electrodes are utilized to monitor process conditions and optimize flotation circuit performance, while the negative effects of Ca2+ and Mg2+ cations on molybdenite flotation in alkaline solutions are addressed along with the need for dispersants and oil collectors to restore floatability. Gangue minerals, particle size, and the impact of oil collectors and surfactants on molybdenite recovery are also discussed in this study.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2021)
Review
Metallurgy & Metallurgical Engineering
Sung Hyuk Park, Ye Jin Kim, Hyun Ji Kim, Sang-Cheol Jin, Jong Un Lee, Alexander Komissarov, Kwang Seon Shin
Summary: This article highlights recent advancements in Mg research in South Korea, including high-speed-extrudable Mg-Bi-based alloys, innovative techniques utilizing {10-12} twinning, and alloying and processing methods for enhanced corrosion resistance.
JOURNAL OF MAGNESIUM AND ALLOYS
(2023)
Article
Biochemistry & Molecular Biology
Devdutta Deb, Ryan G. Anderson, Theresa How-Yew-Kin, Brett M. Tyler, John M. McDowell
MOLECULAR PLANT-MICROBE INTERACTIONS
(2018)
Editorial Material
Biochemistry & Molecular Biology
Wenbo Ma, Yuanchao Wang, John McDowell
MOLECULAR PLANT-MICROBE INTERACTIONS
(2018)
Review
Biochemistry & Molecular Biology
Ronaldo J. D. Dalio, John Herlihy, Tiago S. Oliveira, John M. McDowell, Marcos Machado
MOLECULAR PLANT-MICROBE INTERACTIONS
(2018)
Editorial Material
Biochemistry & Molecular Biology
John M. McDowell
MOLECULAR PLANT-MICROBE INTERACTIONS
(2019)
Article
Plant Sciences
Yan Lai, Alayne Cuzick, Xueqing M. Lu, Jianqiang Wang, Neerja Katiyar, Tokuji Tsuchiya, Karine Le Roch, John M. McDowell, Eric Holub, Thomas Eulgem
Article
Biochemistry & Molecular Biology
Chenming Cui, John H. Herlihy, Aureliano Bombarely, John M. McDowell, David C. Haak
MOLECULAR PLANT-MICROBE INTERACTIONS
(2019)
Article
Biochemical Research Methods
S. Ha, E. Dimitrova, S. Hoops, D. Altarawy, M. Ansariola, D. Deb, J. Glazebrook, R. Hillmer, H. Shahin, F. Katagiri, J. McDowell, M. Megraw, J. Setubal, B. M. Tyler, R. Laubenbacher
BMC BIOINFORMATICS
(2019)
Article
Agronomy
Osman Telli, Catherine Jimenez-Quiros, John M. McDowell, Mahmut Tor
Review
Biochemistry & Molecular Biology
John H. Herlihy, Terri A. Long, John M. McDowell
JOURNAL OF BIOLOGICAL CHEMISTRY
(2020)
Article
Genetics & Heredity
Yan Lai, Xueqing Maggie Lu, Josquin Daron, Songqin Pan, Jianqiang Wang, Wei Wang, Tokuji Tsuchiya, Eric Holub, John M. McDowell, R. Keith Slotkin, Karine G. Le Roch, Thomas Eulgem
Article
Plant Sciences
Julien Besnard, Unnati Sonawala, Bal Maharjan, Eva Collakova, Scott A. Finlayson, Guillaume Pilot, John McDowell, Sakiko Okumoto
Summary: Amino acids play important roles in biosynthesis and signaling, affecting plant development and immune responses. Changes in amino acid levels can trigger stress phenotypes and pathogen resistance through various pathways, indicating a link between amino acid transport and stress responses.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Kasia Dinkeloo, Zoe Pelly, John M. McDowell, Guillaume Pilot
Summary: Translating ribosome affinity purification (TRAP) is a method that uses transgenic plants to purify ribosomes and translating mRNAs. It can be used for studying actively translated mRNAs by quantitative PCR or RNA sequencing. This approach allows researchers to isolate the translatome of specific cell types using condition- or cell-specific promoters. However, it may lack sensitivity in cases where the condition/cell-specific promoter is weak, ribosome turnover is low, or the targeted cells are short-lived. To overcome these limitations, a new TRAP system was developed that utilizes two transgenes and provides increased sensitivity and better temporal resolution.
Review
Plant Sciences
Richard A. Wilson, John M. McDowell
Summary: Fungal and oomycete pathogens secrete proteins and small RNAs to manipulate plant regulatory networks, and research on these factors has advanced our understanding of effector gene expression and effector-triggered immunity mechanisms.
CURRENT OPINION IN PLANT BIOLOGY
(2022)
Review
Plant Sciences
Wei Wang, Jinbao Liu, Bharat Mishra, M. Shahid Mukhtar, John M. McDowell
Summary: This review evaluates the role of sulfur in plant-pathogen interactions, discusses mechanisms of limiting sulfur availability in plants during immune responses, and highlights the potential of genetically manipulating sulfur-related genes for crop resistance.
TRENDS IN PLANT SCIENCE
(2022)
Review
Plant Sciences
Ozlem Bilir, Deniz Gol, Yiguo Hong, John M. McDowell, Mahmut Tor
Summary: Plant diseases have a significant impact on crop yield and quality, posing a threat to food security. Exploiting the RNA interference machinery, particularly through Host-Induced Gene Silencing (HIGS) or Spray-Induced Gene Silencing (SIGS), has shown promising results in combating plant pathogens by generating or applying small RNAs (sRNAs) to silence pathogen genes.
FRONTIERS IN PLANT SCIENCE
(2022)