Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials

The Sodium Pump α1 Subunit as a Potential Target to Combat Apoptosis-Resistant Glioblastomas

(2015) Florence Lefranc et al.   NEOPLASIA

Preoperative Endogenous Ouabain Predicts Acute Kidney Injury in Cardiac Surgery Patients*

(2013) Elena Bignami et al.   CRITICAL CARE MEDICINE

Interaction of atrial natriuretic peptide and ouabain in the myocardium

(2012) Maoz Nesher et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Digoxin-associated decrease in parathyroid hormone (PTH) concentrations in patients with atrial fibrillation

(2012) Arie Apel et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Assembling the puzzle of anti-cancer mechanisms triggered by cardiac glycosides

(2012) Claudia Cerella et al.   MITOCHONDRION

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

(2012) L. Menger et al.   Science Translational Medicine

The Na+-K+-ATPase as self-adhesion molecule and hormone receptor

(2011) M. Cereijido et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

(2011) Qian Zhao et al.   FITOTERAPIA

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation

(2011) Chuan-Ming Xie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiotonic steroids attenuate ERK phosphorylation and generate cell cycle arrest to block human hepatoma cell growth

(2011) Zhong-Wei Xu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

UNBS1450, a steroid cardiac glycoside inducing apoptotic cell death in human leukemia cells

(2010) Tom Juncker et al.   BIOCHEMICAL PHARMACOLOGY

UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death

(2009) Tom Juncker et al.   BIOCHEMICAL PHARMACOLOGY

2′-epi-2′-O-Acetylthevetin B extracted from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

(2009) Bo Feng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

TARGETING THE α 1 SUBUNIT OF THE SODIUM PUMP TO COMBAT GLIOBLASTOMA CELLS

(2009) Florence Lefranc et al.   NEUROSURGERY

Endogenous Cardiotonic Steroids: Physiology, Pharmacology, and Novel Therapeutic Targets

(2009) A. Y. Bagrov et al.   PHARMACOLOGICAL REVIEWS

Nucleolus and c-Myc: potential targets of cardenolide-mediated antitumor activity

(2008) T. Mijatovic et al.   MOLECULAR CANCER THERAPEUTICS

Cardiac Glycosides as Novel Cancer Therapeutic Agents

(2008) R. A. Newman et al.   MOLECULAR INTERVENTIONS