FOXO1 Transcription Factor: A Critical Effector of the PI3K-AKT Axis in B-Cell Development

EBF1 Is Essential for B-Lineage Priming and Establishment of a Transcription Factor Network in Common Lymphoid Progenitors

(2014) S. Zandi et al.   JOURNAL OF IMMUNOLOGY

MK5 activatesRagtranscription via Foxo1 in developing B cells

(2013) Kwan T. Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire

(2012) Sarah L. Rowland et al.   IMMUNOLOGIC RESEARCH

FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination

(2012) Alabbas Alkhatib et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation

(2012) Kyoko Ochiai et al.   NATURE IMMUNOLOGY

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

(2012) R. Mansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia

(2011) Christian Hurtz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Highly Specialized Role of Forkhead Box O Transcription Factors in the Immune System

(2010) Anne S. Dejean et al.   ANTIOXIDANTS & REDOX SIGNALING

Foxo1 regulates marginal zone B-cell development

(2010) Jing Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxo Transcription Factors Control Regulatory T Cell Development and Function

(2010) Yann M. Kerdiles et al.   IMMUNITY

FoxO1: A molecule for all seasons

(2010) Stavroula Kousteni   JOURNAL OF BONE AND MINERAL RESEARCH

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

(2010) Ana V. Miletic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction

(2010) J. Rolf et al.   JOURNAL OF IMMUNOLOGY

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

The p85β regulatory subunit of phosphoinositide 3-kinase has unique and redundant functions in B cells

(2009) Jean S. Oak et al.   AUTOIMMUNITY

Akt1 and Akt2 promote peripheral B-cell maturation and survival

(2009) M. Calamito et al.   BLOOD

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

Activation of SHIP via a small molecule agonist kills multiple myeloma cells

(2009) Michael Kennah et al.   EXPERIMENTAL HEMATOLOGY

Suppression of Phosphatidylinositol 3,4,5-Trisphosphate Production Is a Key Determinant of B Cell Anergy

(2009) Cecille D. Browne et al.   IMMUNITY

BCR-mediated apoptosis associated with negative selection of immature B cells is selectively dependent on Pten

(2008) Shuhua Cheng et al.   CELL RESEARCH

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros

(2008) Damien Reynaud et al.   NATURE IMMUNOLOGY

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

(2008) Rupesh H Amin et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation

(2008) Hart S Dengler et al.   NATURE IMMUNOLOGY