Protein Kinase Cδ Mediates Histamine-Evoked Itch and Responses in Pruriceptors

Protein kinase C pharmacology: refining the toolbox

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The regulation of exon-specific brain-derived neurotrophic factor mRNA expression by protein kinase C in rat cultured dorsal root ganglion neurons

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The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

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Excitation and Modulation of TRPA1, TRPV1, and TRPM8 Channel-expressing Sensory Neurons by the Pruritogen Chloroquine

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Signaling proteins in spinal parenchyma and dorsal root ganglion in rat with spinal injury-induced spasticity

(2013) Helena Kupcova Skalnikova et al.   Journal of Proteomics

Peptidergic CGRPα Primary Sensory Neurons Encode Heat and Itch and Tonically Suppress Sensitivity to Cold

(2013) Eric S. McCoy et al.   NEURON

Chronic Pruritus

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Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1

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Morphology, PKCδ expression, and synaptic responsiveness of different types of rat central lateral amygdala neurons

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The C-Type Natriuretic Peptide Induces Thermal Hyperalgesia through a Noncanonical G  -dependent Modulation of TRPV1 Channel

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Mechanisms of Itch Evoked by  -Alanine

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A subpopulation of nociceptors specifically linked to itch

(2012) Liang Han et al.   NATURE NEUROSCIENCE

Quality of Life and Work Productivity Impairment among Psoriasis Patients: Findings from the National Psoriasis Foundation Survey Data 2003–2011

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Effect of slow-release β-alanine tablets on absorption kinetics and paresthesia

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Prostaglandin E2-prostanoid EP3 signal induces vascular contraction via nPKC and ROCK activation in rat mesenteric artery

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Involvement of Protein Kinase Cδ/Extracellular Signal-regulated Kinase/Poly(ADP-ribose) Polymerase-1 (PARP-1) Signaling Pathway in Histamine-induced Up-regulation of Histamine H1Receptor Gene Expression in HeLa Cells

(2011) Hiroyuki Mizuguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

(2011) Navjotsingh Pabla et al.   JOURNAL OF CLINICAL INVESTIGATION

Specific Involvement of Atypical PKCξ/PKMξ in Spinal Persistent Nociceptive Processing following Peripheral Inflammation in Rat

(2011) Fabien Marchand et al.   Molecular Pain

TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch

(2011) Sarah R Wilson et al.   NATURE NEUROSCIENCE

Histamine H1, H3 and H4 receptors are involved in pruritus

(2011) K. Rossbach et al.   NEUROSCIENCE

The Distinct Roles of Two GPCRs, MrgprC11 and PAR2, in Itch and Hyperalgesia

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Involvement of Lysophosphatidic Acid in Bone Cancer Pain by Potentiation of TRPV1 via PKCe Pathway in Dorsal Root Ganglion Neurons

(2010) Hai-Li Pan et al.   Molecular Pain

Genetic dissection of an amygdala microcircuit that gates conditioned fear

(2010) Wulf Haubensak et al.   NATURE

Derangements of post-ischemic cerebral blood flow by protein kinase C delta

(2010) H.W. Lin et al.   NEUROSCIENCE

The multiple pathways for itch and their interactions with pain

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Epidemiology of Itch: Adding to the Burden of Skin Morbidity

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Prostaglandin E2 induces contraction of liver myofibroblasts by activating EP3 and FP prostanoid receptors

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Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

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A Key Role for gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain

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PKC∊-Dependent Potentiation of TTX-Resistant NaV1.8 Current by Neurokinin-1 Receptor Activation in Rat Dorsal Root Ganglion Neurons

(2009) Chun-Lei Cang et al.   Molecular Pain

Paclitaxel and vinorelbine, evoked the release of substance P from cultured rat dorsal root ganglion cells through different PKC isoform-sensitive ion channels

(2009) Kanako Miyano et al.   NEUROPHARMACOLOGY

Histamine potentiates acid-induced responses mediating transient receptor potential V1 in mouse primary sensory neurons

(2009) Y. Kajihara et al.   NEUROSCIENCE

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating δPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats

(2008) Dora Castañeda et al.   BRAIN RESEARCH

Histamine Induces Egr-1 Expression in Human Aortic Endothelial Cells via the H1 Receptor-mediated Protein Kinase Cδ-dependent ERK Activation Pathway

(2008) Feng Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase C  Is a Critical Regulator of Dopamine Transporter Trafficking and Regulates the Behavioral Response to Amphetamine in Mice

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Histamine-Induced Itch and its Relationship with Pain

(2008) Won-Sik Shim et al.   Molecular Pain

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS

H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes

(2007) Ting-Ting Pan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Morphological characterization of rat Mas-related G-protein-coupled receptor C and functional analysis of agonists

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