The Ras/Raf/Erk Pathway Mediates the Subarachnoid Hemorrhage-Induced Apoptosis of Hippocampal Neurons Through Phosphorylation of p53

Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage

(2015) Yogesh Moradiya et al.   CRITICAL CARE MEDICINE

Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein

(2015) Kazuko Takahashi-Niki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Destabilization of survival factor MEF2D mRNA by neurotoxin in models of Parkinson's disease

(2014) Bao Wang et al.   JOURNAL OF NEUROCHEMISTRY

Possible Role of Raf-1 Kinase in the Development of Cerebral Vasospasm and Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats

(2014) Jian Zhang et al.   MOLECULAR NEUROBIOLOGY

Ceftriaxone alleviates early brain injury after subarachnoid hemorrhage by increasing excitatory amino acid transporter 2 expression via the PI3K/Akt/NF-κB signaling pathway

(2014) D. Feng et al.   NEUROSCIENCE

Loss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathway

(2014) Matthias Drosten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression

(2013) Peter Reinhardt et al.   Cell Stem Cell

Early Brain Injury, an Evolving Frontier in Subarachnoid Hemorrhage Research

(2013) Mutsumi Fujii et al.   Translational Stroke Research

Tetramethylpyrazine induces G0/G1 cell cycle arrest and stimulates mitochondrial-mediated and caspase-dependent apoptosis through modulating ERK/p53 signaling in hepatic stellate cells in vitro

(2012) Feng Zhang et al.   APOPTOSIS

Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits

(2012) Zong Zhuang et al.   BMC NEUROSCIENCE

ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage

(2012) Jee-In Heo et al.   MOLECULAR BIOLOGY REPORTS

Isolation and Culture of Rat Embryonic Neural Cells: A Quick Protocol

(2012) Marco Pacifici et al.   Jove-Journal of Visualized Experiments

ERK mediates anti-apoptotic effect through phosphorylation and cytoplasmic localization of p21Waf1/Cip1/Sdi in response to DNA damage in normal human embryonic fibroblast (HEF) cells

(2010) Jee-In Heo et al.   MOLECULAR BIOLOGY REPORTS

Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus

(2009) He-Ping Tian et al.   BMC NEUROSCIENCE

Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling

(2009) Zhaoyu Jin et al.   CELL

Intensive care treatment of aneurysmal subarachnoid hemorrhage

(2009) Mathieu van der Jagt   CRITICAL CARE MEDICINE

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal

(2009) Federica Catalanotti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

(2008) Jiahao Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway

(2008) Young-Ho Kim et al.   BIOCHEMICAL PHARMACOLOGY

Betulinic Acid for Cancer Treatment and Prevention

(2008) Simone Fulda   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY