Nanoparticles Exacerbate Both Ubiquitin and Heat Shock Protein Expressions in Spinal Cord Injury: Neuroprotective Effects of the Proteasome Inhibitor Carfilzomib and the Antioxidant Compound H-290/51

Hyperhomocysteinemia-induced oxidative stress differentially alters proteasome composition and activities in heart and aorta

(2014) Faouzia Derouiche et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Consensus of Clinical Neurorestorative Progress in Patients with Complete Chronic Spinal Cord Injury

(2014) Hongyun Huang et al.   CELL TRANSPLANTATION

Amyloid Transition of Ubiquitin on Silver Nanoparticles Produced by Pulsed Laser Ablation in Liquid as a Function of Stabilizer and Single-Point Mutations

(2014) Vincenzo Mangini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Molecular Pathways: Turning Proteasomal Protein Degradation into a Unique Treatment Approach

(2014) S. Stintzing et al.   CLINICAL CANCER RESEARCH

The ubiquitin–proteasome system: opportunities for therapeutic intervention in solid tumors

(2014) Daniel E Johnson   ENDOCRINE-RELATED CANCER

Titanium dioxide nanoparticles induce strong oxidative stress and mitochondrial damage in glial cells

(2014) Elizabeth Huerta-García et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endoplasmic Reticulum-associated Degradation of Niemann-Pick C1

(2014) Naoe Nakasone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spinal Cord Injury and the Neuron-Intrinsic Regeneration-Associated Gene Program

(2014) Nitish D. Fagoe et al.   NEUROMOLECULAR MEDICINE

Blast-Related Mild Traumatic Brain Injury: A Bayesian Random-Effects Meta-Analysis on the Cognitive Outcomes of Concussion among Military Personnel

(2014) Justin E. Karr et al.   NEUROPSYCHOLOGY REVIEW

0277 Environmental exposure to nanoparticles in Sardinia, Italy: a pilot study of residential exposure nearby an industrial area and a military shooting range

(2014) Marcello Campagna et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Carfilzomib and Pomalidomide: Recent Advances in the Treatment of Multiple Myeloma

(2014) Kaitlin N. Highsmith et al.   PHARMACOTHERAPY

Effects of Oxidative Stress on the Solubility of HRD1, a Ubiquitin Ligase Implicated in Alzheimer’s Disease

(2014) Ryo Saito et al.   PLoS One

Significance of Ubiquitin Carboxy-Terminal Hydrolase L1 Elevations in Athletes after Sub-Concussive Head Hits

(2014) Vikram Puvenna et al.   PLoS One

Small Ubiquitin-Like Modifier 3–Modified Proteome Regulated by Brain Ischemia in Novel Small Ubiquitin-Like Modifier Transgenic Mice

(2014) Wei Yang et al.   STROKE

The ubiquitin proteasome system in glia and its role in neurodegenerative diseases

(2014) Anne H. P. Jansen et al.   Frontiers in Molecular Neuroscience

Ubiquitin pathways in neurodegenerative disease

(2014) Graham Atkin et al.   Frontiers in Molecular Neuroscience

New perspectives of nanoneuroprotection, nanoneuropharmacology and nanoneurotoxicity: modulatory role of amino acid neurotransmitters, stress, trauma, and co-morbidity factors in nanomedicine

(2013) Hari S. Sharma et al.   AMINO ACIDS

Intracellular protein degradation: From a vague idea through the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

(2013) Aaron Ciechanover   BIOORGANIC & MEDICINAL CHEMISTRY

Characterization of spinal injuries sustained by American service members killed in Iraq and Afghanistan

(2013) Andrew J. Schoenfeld et al.   Journal of Trauma and Acute Care Surgery

Size- and Age-Dependent Neurotoxicity of Engineered Metal Nanoparticles in Rats

(2013) Aruna Sharma et al.   MOLECULAR NEUROBIOLOGY

Exacerbation of Brain Pathology After Partial Restraint in Hypertensive Rats Following SiO2 Nanoparticles Exposure at High Ambient Temperature

(2013) Hari S. Sharma et al.   MOLECULAR NEUROBIOLOGY

Spinal Injuries in United States Military Personnel Deployed to Iraq and Afghanistan

(2013) Andrew J. Schoenfeld et al.   SPINE

Docking of Ubiquitin to Gold Nanoparticles

(2012) Giorgia Brancolini et al.   ACS Nano

Generation of free ubiquitin chains is up-regulated in stress and facilitated by the HECT domain ubiquitin ligases UFD4 and HUL5

(2012) Ori Braten et al.   BIOCHEMICAL JOURNAL

Cerebrolysin, a Mixture of Neurotrophic Factors Induces Marked Neuroprotection in Spinal Cord Injury Following Intoxication of Engineered Nanoparticles from Metals

(2012) Preeti Kumaran Menon et al.   CNS & Neurological Disorders-Drug Targets

Spinal Column Injuries Among Americans in the Global War on Terrorism

(2012) James A Blair et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation

(2012) Y.-J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Ras-GTPase Farnesylation and the Ubiquitin-Proteasome System or Treatment with Angiotensin-(1–7) Attenuates Spinal Cord Injury-Induced Cardiac Dysfunction

(2011) Ibrahim F. Benter et al.   JOURNAL OF NEUROTRAUMA

Serum levels of neuron-specific ubiquitin carboxyl-terminal esterase-L1 predict brain injury in a canine model of hypothermic circulatory arrest

(2011) George J. Arnaoutakis et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

(2011) Allan M. Weissman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nanowired drug delivery for neuroprotection in central nervous system injuries: modulation by environmental temperature, intoxication of nanoparticles, and comorbidity factors

(2011) Hari Shanker Sharma et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Expression of heat shock protein (HSP 72 kDa) during acute methamphetamine intoxication depends on brain hyperthermia: neurotoxicity or neuroprotection?

(2010) Eugene A. Kiyatkin et al.   JOURNAL OF NEURAL TRANSMISSION

Early microvascular reactions and blood–spinal cord barrier disruption are instrumental in pathophysiology of spinal cord injury and repair: novel therapeutic strategies including nanowired drug delivery to enhance neuroprotection

(2010) Hari Shanker Sharma   JOURNAL OF NEURAL TRANSMISSION

Protein−Nanoparticle Interaction: Identification of the Ubiquitin−Gold Nanoparticle Interaction Site

(2010) Luigi Calzolai et al.   NANO LETTERS

Chronic Treatment with Nanoparticles Exacerbate Hyperthermia Induced Blood-Brain Barrier Breakdown, Cognitive Dysfunction and Brain Pathology in the Rat. Neuroprotective Effects of Nanowired-Antioxidant Compound H-290/51

(2009) Hari Shanker Sharma et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Silicon Dioxide Nanoparticles (SiO2, 40–50 nm) Exacerbate Pathophysiology of Traumatic Spinal Cord Injury and Deteriorate Functional Outcome in the Rat. An Experimental Study Using Pharmacological and Morphological Approaches

(2009) Hari Shanker Sharma et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Influence of Engineered Nanoparticles from Metals on the Blood-Brain Barrier Permeability, Cerebral Blood Flow, Brain Edema and Neurotoxicity. An Experimental Study in the Rat and Mice Using Biochemical and Morphological Approaches

(2009) Hari S. Sharma et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Military Traumatic Brain and Spinal Column Injury: A 5-Year Study of the Impact Blast and Other Military Grade Weaponry on the Central Nervous System

(2009) Randy S. Bell et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

New perspectives for the treatment options in spinal cord injury

(2008) Hari Shanker Sharma   EXPERT OPINION ON PHARMACOTHERAPY

Ubiquitin-Mediated Stress Response in the Spinal Cord After Transient Ischemia

(2008) Takashi Yamauchi et al.   STROKE