A coiled coil switch mediates cold sensing by the thermosensory protein DesK

Activation of the bacterial thermosensor DesK involves a serine zipper dimerization motif that is modulated by bilayer thickness

(2015) Larisa Estefanía Cybulski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helix-Helix Interactions: Is the Medium the Message?

(2015) Charles M. Deber et al.   STRUCTURE

The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions

(2015) Shao-Qing Zhang et al.   STRUCTURE

Signal Transduction in Histidine Kinases: Insights from New Structures

(2015) Manasi P. Bhate et al.   STRUCTURE

Temperature Sensing by Membranes

(2014) Diego de Mendoza   Annual Review of Microbiology

A lipid-mediated conformational switch modulates the thermosensing activity of DesK

(2014) María Eugenia Inda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cys-Scanning Disulfide Crosslinking and Bayesian Modeling Probe the Transmembrane Signaling Mechanism of the Histidine Kinase, PhoQ

(2014) Kathleen S. Molnar et al.   STRUCTURE

Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation

(2014) Felipe Trajtenberg et al.   mBio

Mutational analysis of dimeric linkers in peri- and cytoplasmic domains of histidine kinase DctB reveals their functional roles in signal transduction

(2014) J. Liu et al.   Open Biology

Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

(2014) Ariel E. Mechaly et al.   PLOS BIOLOGY

Cerulenin inhibits unsaturated fatty acids synthesis inBacillus subtilisby modifying the input signal of DesK thermosensor

(2014) Lucía Porrini et al.   MicrobiologyOpen

Regulation ofBacillus subtilisDesK thermosensor by lipids

(2013) Mariana Martín et al.   BIOCHEMICAL JOURNAL

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Full-Length Structure of a Sensor Histidine Kinase Pinpoints Coaxial Coiled Coils as Signal Transducers and Modulators

(2013) Ralph P. Diensthuber et al.   STRUCTURE

Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains

(2013) Chen Wang et al.   PLOS BIOLOGY

Assembly of the Transmembrane Domain of E. coli PhoQ Histidine Kinase: Implications for Signal Transduction from Molecular Simulations

(2013) Thomas Lemmin et al.   PLoS Computational Biology

Hydrophobic Matching Controls the Tilt and Stability of the Dimeric Platelet-derived Growth Factor Receptor (PDGFR) β Transmembrane Segment

(2012) Claudia Muhle-Goll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Extension and Further Validation of an All-Atomistic Force Field for Biological Membranes

(2012) Joakim P. M. Jämbeck et al.   Journal of Chemical Theory and Computation

Structural basis of histidine kinase autophosphorylation deduced by integrating genomics, molecular dynamics, and mutagenesis

(2012) A. E. Dago et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Temperature on the Structure of Charged Membranes

(2011) Pablo Szekely et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Biological membranes: the importance of molecular detail

(2011) Anthony G. Lee   TRENDS IN BIOCHEMICAL SCIENCES

Membrane Thickness Cue for Cold Sensing in a Bacterium

(2010) Larisa E. Cybulski et al.   CURRENT BIOLOGY

Structural and Enzymatic Insights into the ATP Binding and Autophosphorylation Mechanism of a Sensor Histidine Kinase

(2010) Felipe Trajtenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probing Designability via a Generalized Model of Helical Bundle Geometry

(2010) Gevorg Grigoryan et al.   JOURNAL OF MOLECULAR BIOLOGY

The Temperature Dependence of Lipid Membrane Permeability, its Quantized Nature, and the Influence of Anesthetics

(2009) Andreas Blicher et al.   BIOPHYSICAL JOURNAL

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

(2009) D. Albanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional in vitro assembly of the integral membrane bacterial thermosensor DesK

(2009) Mariana Martín et al.   PROTEIN EXPRESSION AND PURIFICATION

Membrane Hydrocarbon Thickness Modulates the Dynamics of a Membrane Transport Protein

(2008) Qi Xu et al.   BIOPHYSICAL JOURNAL

Structural specificity in coiled-coil interactions

(2008) G GRIGORYAN et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Design and Signaling Mechanism of Light-Regulated Histidine Kinases

(2008) Andreas Möglich et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane lipid homeostasis in bacteria

(2008) Yong-Mei Zhang et al.   NATURE REVIEWS MICROBIOLOGY

Temperature Dependence of Structure, Bending Rigidity, and Bilayer Interactions of Dioleoylphosphatidylcholine Bilayers

(2007) Jianjun Pan et al.   BIOPHYSICAL JOURNAL