期刊
INTERNATIONAL JOURNAL OF TOXICOLOGY
卷 32, 期 3, 页码 5S-24S出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1091581813486299
关键词
silylates
资金
- Cosmetic Ingredient Review
- Personal Care Products Council
The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of silica silylate, silica dimethyl silylate, trimethylsiloxysilicate, and trifluoropropyldimethyl/trimethylsiloxysilicate as used in cosmetics. These silylates and surface-modified siloxysilicates function in cosmetics as antifoaming agents, anticaking agents, bulking agents, binders, skin-conditioning agentsemollient, skin-conditioning agentsocclusive, slip modifiers, suspension agentsnonsurfactant, and viscosity increasing agentsnonaqueous. The Expert Panel reviewed the available animal and clinical data as well as information from a previous CIR safety assessment of amorphous silica. The CIR Expert Panel concluded that silica silylate, silica dimethyl silylate, trimethylsiloxysilicate, and trifluoropropyldimethyl/trimethylsiloxysilicate are safe as used when formulated and delivered in the final product not to be irritating or sensitizing to the respiratory tract.
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