Multiplexed High Content Screening Reveals That Cigarette Smoke Condensate-Altered Cell Signaling Pathways Are Accentuated Through FAK Inhibition in Human Bronchial Cells

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer

(2011) Steven N. Hochwald et al.   CELL CYCLE

Cigarette Smoke Extracts Promote Vascular Smooth Muscle Cell Proliferation and Enhances Contractile Responses in the Vasculature and Airway

(2010) Cang-Bao Xu et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Chemoresistance of lung cancer stemlike cells depends on activation of Hsp27

(2010) Han-Shui Hsu et al.   CANCER

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

(2010) Isabelle Tanjoni et al.   CANCER BIOLOGY & THERAPY

Effects of Short-Term Cigarette Smoke Exposure on Fischer 344 Rats and on Selected Lung Proteins

(2010) Charleata A. Carter et al.   TOXICOLOGIC PATHOLOGY

Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion

(2009) X N Meng et al.   BRITISH JOURNAL OF CANCER

Bronchial Airway Epithelial Cell Damage Following Exposure to Cigarette Smoke Includes Disassembly of Tight Junction Components Mediated by the Extracellular Signal-Regulated Kinase 1/2 Pathway

(2009) Loredana Petecchia et al.   CHEST

FAK engages multiple pathways to maintain survival of fibroblasts and epithelia - differential roles for paxillin and p130Cas

(2009) N. K. Zouq et al.   JOURNAL OF CELL SCIENCE

A Randomized, Placebo-Controlled Study of the Effects of the p38 MAPK Inhibitor SB-681323 on Blood Biomarkers of Inflammation in COPD Patients

(2009) Dave Singh et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Urban Particulate Matter Causes ER Stress and the Unfolded Protein Response in Human Lung Cells

(2009) Todd L. Watterson et al.   TOXICOLOGICAL SCIENCES

Multiplexed quantitative high content screening reveals that cigarette smoke condensate induces changes in cell structure and function through alterations in cell signaling pathways in human bronchial cells

(2009) Charleata A. Carter et al.   TOXICOLOGY

A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals

(2008) Vernonica E. Franklin-Tong et al.   BIOCHEMICAL JOURNAL

HSP27 regulates cell adhesion and invasion via modulation of focal adhesion kinase and MMP-2 expression

(2008) Joong-Won Lee et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cigarette smoke-induced left ventricular remodelling is associated with activation of mitogen-activated protein kinases

(2008) Lianzhi Gu et al.   EUROPEAN JOURNAL OF HEART FAILURE

Disruption of FAK signaling: A side mechanism in cytotoxicity

(2008) Nikolaos A. Chatzizacharias et al.   TOXICOLOGY