期刊
MOLECULAR MEMBRANE BIOLOGY
卷 32, 期 5-8, 页码 179-188出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09687688.2016.1182652
关键词
Glutamate receptor; acylation; signaling; phosphorylation; palmitoylation
资金
- NIH [R21NS087414, R01NS094402]
- Shriners Hospitals for Children [85600, 86610]
Modification of proteins with the lipid palmitate, a process called palmitoylation, is important for the normal function of neuronal cells. However, most attention has focused on how palmitoylation regulates the targeting and trafficking of neurotransmitter receptors and nonenzymatic scaffold proteins. In this review we discuss recent studies that suggest that palmitoylation also plays additional roles in neurons by controlling the localization, interactions and perhaps even the activity of protein kinases that play key roles in physiological neuronal regulation and in neuropathological processes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据