Tenecteplase for the treatment of acute ischemic stroke: A review of completed and ongoing randomized controlled trials

Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke

(2018) Bruce C.V. Campbell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Penumbral Imaging-Based Thrombolysis with Tenecteplase Is Feasible up to 24 Hours after Symptom Onset

(2018) Mahesh Kate et al.   Journal of Stroke

Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials

(2017) Werner Hacke et al.   International Journal of Stroke

Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial

(2017) Nicola Logallo et al.   LANCET NEUROLOGY

Tenecteplase in ischemic stroke offers improved recanalization

(2017) Andrew Bivard et al.   NEUROLOGY

Too good to treat? ischemic stroke patients with small computed tomography perfusion lesions may not benefit from thrombolysis

(2016) Andrew Bivard et al.   ANNALS OF NEUROLOGY

Impact of Computed Tomography Perfusion Imaging on the Response to Tenecteplase in Ischemic StrokeClinical Perspective

(2016) Andrew Bivard et al.   CIRCULATION

Tenecteplase versus alteplase in stroke thrombolysis: An individual patient data meta-analysis of randomized controlled trials

(2016) Xuya Huang et al.   International Journal of Stroke

Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis

(2016) William N Whiteley et al.   LANCET NEUROLOGY

Desmoteplase 3 to 9 Hours After Major Artery Occlusion Stroke

(2016) Rüdiger von Kummer et al.   STROKE

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke

(2016) Grant Mair et al.   STROKE

Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes

(2016) Kennedy R. Lees et al.   STROKE

Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (ATTEST): a phase 2, randomised, open-label, blinded endpoint study

(2015) Xuya Huang et al.   LANCET NEUROLOGY

Safety and efficacy of desmoteplase given 3–9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): a double-blind, randomised, placebo-controlled phase 3 trial

(2015) Gregory W Albers et al.   LANCET NEUROLOGY

Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke

(2015) Mayank Goyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

(2015) Bruce C.V. Campbell et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

(2015) Olvert A. Berkhemer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tenecteplase–Tissue-Type Plasminogen Activator Evaluation for Minor Ischemic Stroke With Proven Occlusion

(2015) Shelagh B. Coutts et al.   STROKE

Coagulation and Fibrinolytic Activity of Tenecteplase and Alteplase in Acute Ischemic Stroke

(2015) Xuya Huang et al.   STROKE

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

Presentation and Outcomes of “Wake-Up Strokes” in a Large Randomized Stroke Trial: Analysis of Data from the International Stroke Trial

(2012) Yogesh Moradiya et al.   Journal of Stroke & Cerebrovascular Diseases

A Randomized Trial of Tenecteplase versus Alteplase for Acute Ischemic Stroke

(2012) Mark Parsons et al.   NEW ENGLAND JOURNAL OF MEDICINE

Refinement of the Magnetic Resonance Diffusion-Perfusion Mismatch Concept for Thrombolytic Patient Selection

(2012) Steven Warach et al.   STROKE

Vascular Occlusion Enables Selecting Acute Ischemic Stroke Patients for Treatment With Desmoteplase

(2012) Jochen B. Fiebach et al.   STROKE

Timing of Recanalization After Intravenous Thrombolysis and Functional Outcomes After Acute Ischemic Stroke

(2012) Leonard L. L. Yeo et al.   JAMA Neurology

Population-based study of wake-up strokes

(2011) J. Mackey et al.   NEUROLOGY

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

(2010) Kennedy R Lees et al.   LANCET

Low Rates of Acute Recanalization With Intravenous Recombinant Tissue Plasminogen Activator in Ischemic Stroke

(2010) Rohit Bhatia et al.   STROKE

Thrombolysis Is Associated With Consistent Functional Improvement Across Baseline Stroke Severity

(2010) Nishant K. Mishra et al.   STROKE

Phase IIB/III Trial of Tenecteplase in Acute Ischemic Stroke

(2010) E. Clarke Haley et al.   STROKE

Acute ischemic stroke: Imaging-guided tenecteplase treatment in an extended time window

(2009) M. W. Parsons et al.   NEUROLOGY

Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion–diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study

(2008) Werner Hacke et al.   LANCET NEUROLOGY