Article
Multidisciplinary Sciences
Weiyong Chen, Xin Zhou, Qiaoqin Ma, Lin He, Wanjun Chen, Zhihong Guo, Lin Chen
Summary: Consistent condom use among male university students in eastern China was found to be low. Factors associated with higher rates of consistent condom use include increased knowledge about HIV infection, reduced web-based casual sex, abstaining from drinking alcohol before casual sex, avoiding commercial sex, and having high condom self-efficacy scores. Promoting these factors is crucial to improve the level of consistent condom use and reduce the transmission of HIV among male university students.
Article
Multidisciplinary Sciences
Zhongrong Yang, Weiyong Chen, Meihua Jin, Wanjun Chen, Lin Chen, Xin Zhou
Summary: The study found that male college students engaging in casual sexual behaviors have relatively open sexual attitudes, insufficient knowledge of AIDS prevention, and awareness of HIV testing information but low testing rates. Therefore, it is necessary to emphasize the establishment of correct sexual attitudes and concepts and promote safe sexual behaviors to prevent the spread of HIV.
Article
Psychology, Multidisciplinary
R. Nathan Pipitone, Lesley Cruz, Helen N. Morales, Daniela Aladro, Serena R. Savitsky, Maria Koroleva, Francesca Valdez, Erin Campbell, Sam Miranda
Summary: Research shows that males are more likely to engage in casual sex compared to females, particularly in scenarios with lower STI contraction likelihoods and high partner attractiveness. However, as STI risks increase and partner attractiveness decreases, sex differences diminish. Individual levels of sociosexuality play a role in influencing these findings.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Endocrinology & Metabolism
Mingxing Chang, Zhihao Shao, Wei Wei, Peipu Shen, Guifang Shen
Summary: MAFLD is prevalent in the general adult population in eastern China. Sex-specific differences in MAFLD prevalence were identified based on age, BMI, and metabolic disorders. MAFLD is associated with metabolic disorders, particularly obesity.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Maohe Yu, Desheng Song, Tiantian Zhang, Tingting Yao, Yang Chen, Yuanyuan Liu, Elissa Peixoto, Jie Xu, Zhijun Li, Jie Yang, Changping Li, Zhuang Cui
Summary: The study found that male sex workers (MSWs) had a higher HIV infection rate compared to men who have sex with men (MSM), and there were significant differences in characteristics and risk factors between the two groups. MSWs were younger, more likely to live alone, have lower education levels, more likely to use drugs, had higher proportion of condom use during anal sex, but lower proportion during commercial sex.
Article
Public, Environmental & Occupational Health
Liqing Wei, Jiawei Tian, Menglan Guo, Biao Zhu, Qingqing Jiang, Bin Yu, Hong Yan
Summary: Sexual risk behaviors among young men who have sex with men (YMSM) in China change over time within different trajectories. Identifying YMSM belonging to high-risk trajectories is crucial for preventing HIV transmission.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Biochemistry & Molecular Biology
Elvira Delcuratolo, Alberto Palazzuoli, Francesca Coppi, Anna Vittoria Mattioli, Paolo Severino, Francesco Tramonte, Francesco Fedele
Summary: Patients with heart failure are conventionally stratified based on their ejection fraction and gender, as there may be significant differences in the onset, development, and clinical course of the disease between males and females. Despite these differences, treatment for heart failure is similar across the whole population.
Article
Medicine, Research & Experimental
Simona Hankeova, Noemi Van Hul, Jakub Laznovsky, Elisabeth Verboven, Katrin Mangold, Naomi Hensens, Csaba Adori, Elvira Verhoef, Tomas Zikmund, Feven Dawit, Michaela Kavkova, Jakub Salplachta, Marika Sjoqvist, Bengt R. Johansson, Mohamed G. Hassan, Linda Fredriksson, Karsten Baumgartel, Vitezslav Bryja, Urban Lendahl, Andrew Jheon, Florian Alten, Kristina Tear Fahnehjelm, Bjorn Fischler, Jozef Kaiser, Emma R. Andersson
Summary: This study found significant sex differences in spontaneous bleeding events reported by ALGS patients, with more girls than boys experiencing intracranial hemorrhage. Jag1(Ndr/Ndr) mice displayed various vascular defects, and retinography proved to be a non-invasive method to analyze vascular changes in patients.
EMBO MOLECULAR MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Winston E. Abara, Maria Zlotorzynska, Robert D. Kirkcaldy, Travis Sanchez
Summary: The study found a connection between prescription opioid misuse and increased risk of bacterial sexually transmitted diseases among men who have sex with men. However, the reported rate of bacterial STD testing in this population was low, highlighting the need for innovative approaches to increase testing rates.
ANNALS OF EPIDEMIOLOGY
(2021)
Article
Oncology
Christopher W. Wheldon, Elizabeth Polter, B. R. Simon Rosser, Alex J. Bates, Ryan Haggart, Morgan Wright, Darryl Mitteldorf, Michael W. Ross, Badrinath R. Konety, Nidhi Kohli, Kristine M. C. Talley, William West, Alexander K. Tatum
Summary: This study examined the prevalence of sexually transmitted infections (STIs) and risk factors among gay and bisexual male (GBM) prostate cancer survivors. The results showed that GBM prostate cancer survivors are at higher risk for STIs, with syphilis, gonorrhoea, and chlamydia being the most commonly diagnosed infections. Independent risk factors for STI diagnosis included time since prostate cancer diagnosis, nonmonogamous sexual relationship, better sexual function, penile injection treatment, and multiple sex partners.
FRONTIERS IN ONCOLOGY
(2022)
Letter
Medicine, General & Internal
Yilin Yoshida, Zhipeng Chen, Robin L. Baudier, Marie Krousel-Wood, Amanda H. Anderson, Vivian A. Fonseca, Franck Mauvais-Jarvis
Summary: This study uses data from the ARIC Study to examine whether the increase in metabolic syndrome severity is more prominent in women than men and if this sex difference varies by race.
Review
Medicine, General & Internal
Anna Louise Pouncey, Mark Woodward
Summary: Cardiovascular disease is the leading cause of death in women, with ischaemic heart disease, stroke, and peripheral arterial disease being major components. However, there is a lack of knowledge about the risk factors and efficacy of treatment in women, resulting in reduced opportunities for prevention and management.
Article
Medicine, General & Internal
Yumei Wu, Hui Zeng, Meiping Zhang, Chunyan Li, Yuanlin Tang, Xiufen Li, Shanyou Yuan, Qifeng Wei, Jinghua Wang, Xianjia Ning, Xiaoyin Zhang
Summary: This study investigated the sex-specific differences in the prevalence of H. pylori infection and its associated factors in individuals undergoing hospital-based health examinations in southern China. The results showed minor differences in infection rates between men and women, as well as differences in risk factors.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2022)
Article
Behavioral Sciences
Rui Zhong, Qingling Chen, Nan Li, Xinyue Zhang, Weihong Lin
Summary: This study confirmed that female patients with epilepsy are more likely to experience severe depressive symptoms compared to males. Risk factors for depression in epileptic patients vary between sexes, and the association between cognitive function and depression is influenced by patient sex.
EPILEPSY & BEHAVIOR
(2021)
Article
Clinical Neurology
Helen Bradshaw, Julia N. Riddle, Rodion Salimgaraev, Liudmila Zhaunova, Jennifer L. Payne
Summary: This study aimed to evaluate the association between maternal age, parity, gestational number, newborn gender and postpartum depressive symptoms. The results showed that postpartum depressive symptoms decreased with advancing age. First-time mothers reported higher rates of depressive symptoms. Twin births were associated with a higher symptom burden than singleton births, and mothers of twins in the oldest age group reported the greatest burden. There was no clinically significant difference in rates of depressive symptoms between mothers of singleton girls and boys.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Biochemistry & Molecular Biology
Alice Lu-Culligan, Alexandra Tabachnikova, Eddy Perez-Then, Maria Tokuyama, Hannah J. Lee, Carolina Lucas, Valter Silva Monteiro, Marija Miric, Vivian Brache, Leila Cochon, M. Catherine Muenker, Subhasis Mohanty, Jiefang Huang, Insoo Kang, Charles Dela Cruz, Shelli Farhadian, Melissa Campbell, Inci Yildirim, Albert C. Shaw, Shuangge Ma, Sten H. Vermund, Albert Ko, Saad B. Omer, Akiko Iwasaki
Summary: This study found that COVID-19 mRNA vaccination during early pregnancy does not lead to birth defects or growth abnormalities in mice, and does not cause overt maternal illness. Furthermore, it was observed that there is transplacental transfer of antibodies in the later stages of pregnancy after early immunization. Additionally, no increased levels of anti-syncytin-1 antibodies were detected in vaccinated adults.
Review
Infectious Diseases
Dayong Huang, Jiawulan Zunong, Menglong Li, Dan Li, JiaJian Gong, Sten H. Vermund, Yifei Hu
Summary: Through a review of COVID-19 and HIV coinfection cases in China, it was found that males and older individuals were more susceptible to infection. Common symptoms included fatigue, respiratory distress, and gastrointestinal symptoms. Early use of antiretroviral therapy was associated with a better prognosis for COVID-19, but the sample size was small.
CURRENT HIV/AIDS REPORTS
(2022)
Article
Immunology
Palizhati Rehati, Nubiya Amaerjiang, Liping Yang, Huidi Xiao, Menglong Li, Jiawulan Zunong, Long Wang, Sten H. Vermund, Yifei Hu
Summary: Chinese students showed hesitancy and resistance towards the COVID-19 vaccine, which is associated with limited health literacy and lower risk awareness. Educating youth about the safety and effectiveness of the vaccine can reduce concerns and increase acceptance.
Article
Public, Environmental & Occupational Health
Natasha Turyasingura, Wilmot G. James, Sten H. Vermund
Summary: The COVID-19 pandemic has been the main topic in global health discussions since early 2020. Vaccine development against SARS-CoV-2 has been successful, but the distribution has not been fair, especially in African countries. This article highlights the low vaccination rates in Africa and suggests Africa-based research and development as a sustainable solution for vaccine equity.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
(2023)
Article
Immunology
Blia Yang, Rosa Sloot, Sian Floyd, Dolapo Awoniyi, Sam Griffith, Helen Ayles, Sarah Fidler, Richard H. Hayes, Sten Vermund, Peter Bock
Summary: A study conducted in South Africa found that conducting household visits during the weekends increased the number of men and women participating in the HIV testing program. This suggests that targeting households during the weekend can be an effective and easy-to-implement strategy to increase the number of men accessing HIV testing.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2023)
Article
Cell Biology
Bruno Andraus Filardi, Valter Silva Monteiro, Pedro Vellosa Schwartzmann, Vivian do Prado Martins, Luis Eduardo Rosa Zucca, Gabriela Crispim Baiocchi, Amyn A. Malik, Julio Silva, Anne M. Hahn, Nicholas F. G. Chen, Kien Pham, Eddy Perez-Then, Marija Miric, Vivian Brache, Leila Cochon, Rafael A. Larocca, Roberto Della Rosa Mendez, Douglas Bardini Silveira, Aguinaldo Roberto Pinto, Julio Croda, Inci Yildirim, Saad B. Omer, Albert I. Ko, Sten H. Vermund, Nathan D. Grubaugh, Akiko Iwasaki, Carolina Lucas
Summary: The emergence of the SARS-CoV-2 Omicron sublineages resulted in increased transmission rates and reduced vaccine protection. Homologous CoronaVac booster doses showed lower efficiency in enhancing immune response compared to heterologous BNT162b2 or ChAdOx1 boosters, especially in individuals over 50 years old. These findings emphasize the potential benefits of heterologous vaccination strategies for older adults fully vaccinated with CoronaVac during the Omicron wave.
SCIENCE TRANSLATIONAL MEDICINE
(2023)
Article
Virology
Ainur Sanaubarova, Emma Pujol-Hodge, Natalya Dzissyuk, Philippe Lemey, Sten H. Vermund, Andrew J. Leigh J. Brown, Syed Ali
Summary: HIV incidence in Kazakhstan increased by 73% between 2010 and 2020, with an estimated 35,000 people living with HIV (PLHIV) in 2020. Studies on the prevalence of drug resistance in Kazakhstan are sparse. In this study, we analyzed 968 HIV-1 pol sequences collected between 2017 and 2020, representing almost 3% of PLHIV in 2020. The study revealed high levels of drug resistance and differential drug-resistant mutations (DRMs) frequencies between subtypes, emphasizing the need for drug resistance monitoring and tailored drug regimens.
Article
Cardiac & Cardiovascular Systems
Wen Shu, Menglong Li, Huidi Xiao, Nubiya Amaerjiang, Nourhan M. Khattab, Jiawulan Zunong, Mengying Guan, Sten H. Vermund, Yifei Hu
Summary: This study investigated children aged 6 to 10 from 6 elementary schools in Beijing, collecting data on the Life's Essential 8 (LE8) metrics and cardiovascular structural parameters. The findings showed a decline in cardiovascular health scores with age.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Immunology
Eddy Perez-Then, Marija Miric, Han-Zhu Qian, Ying Qing Chen, Yixin Wang, Virginia Vallejo, Wanda Quezada, Melissa Flaquer, Juan Olivo, Jean Castillo, Natalia Garcia, Katherine Calderon, Scarlet Cueto, Bienvenido Veras, Miguel Russo, Indira Jimenez, Sorileydi Guzman, Luz Garabito, Evelyn Cueto, Fatima Colombo, Dominga Taveras, Dania Torres, Jeannette Baez, Jose Yunen, Ellen Koenig, Eladio Perez, Oscar Lopez, Fior Estephanie Severino Medina, Xuanyi Wang, Yiming Shao, Sten H. Vermund
Summary: A nationwide vaccination campaign using the inactivated vaccine (CoronaVac) in the Dominican Republic showed that full immunization and partial immunization can reduce the risk of symptomatic SARS-CoV-2 infection and hospitalization.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Dan Li, Tyler Shelby, Marie Brault, Rajit Manohar, Sten Vermund, Ashley Hagaman, Laura Forastiere, Tyler Caruthers, Emilie Egger, Yizhou Wang, Nathan Manohar, Peter Manohar, J. Lucian Davis, Xin Zhou
Summary: This study aimed to address the limitations of traditional interview-format contact tracing (TCT) by using a Hardware-Assisted Bluetooth-based Infection Tracking (HABIT) device. The implementation of HABIT in a high school setting was evaluated, and it was found that the device identified a significant number of unique contacts not reported by interview. However, technical difficulties hindered the implementation and sustained use of HABIT.
JMIR FORMATIVE RESEARCH
(2023)
Article
Immunology
Kimberly A. Powers, Wilbroad Mutale, Nora E. Rosenberg, Lauren A. Graybill, Katie R. Mollan, Kellie Freeborn, Friday Saidi, Suzanne Maman, Priscilla L. Mulenga, Andreas Jahn, Rose K. Nyirenda, Jeffrey S. A. Stringer, Sten H. Vermund, Benjamin H. Chi
Summary: Despite the success in reducing vertical HIV transmission, most ANC programs in eastern and southern Africa have not focused on preventing maternal HIV acquisition during pregnancy and breastfeeding. The study suggests that implementing combination HIV prevention interventions alongside ANC could greatly reduce maternal HIV incidence.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2023)
Article
Nutrition & Dietetics
Huidi Xiao, Wen Shu, Menglong Li, Liyuan Xu, Nubiya Amaerjiang, Jiawulan Zunong, Sten H. Vermund, Dayong Huang, Mei Chong, Yifei Hu
Summary: This study aimed to assess the effects of sex and overweight/obesity on left ventricular mass (LVM) and left ventricular volume in Chinese children. The results showed that higher BMI, fat mass, waist circumference, visceral fat area, and stroke volume predicted higher LVM, left ventricle end-diastolic volume (LVEDV), and end-systolic volume (LVESV) in both boys and girls. Boys with elevated BMI had greater left ventricular hypertrophy. LVEDV and LVESV were higher in boys than in girls and increased with higher BMI in both genders. LVEDV and LVESV were associated with visceral fat area in boys.
Article
Immunology
Hagit Kopel, Van Hung Nguyen, Catherine Boileau, Alina Bogdanov, Isabelle Winer, Thierry Ducruet, Ni Zeng, Mac Bonafede, Daina B. Esposito, David Martin, Andrew Rosen, Nicolas van de Velde, Sten H. Vermund, Stefan Gravenstein, James A. Mansi
Summary: This study used a nationwide dataset in the US to estimate the relative effectiveness (rVE) of two mRNA vaccines (mRNA-1273.222 and BNT162b2 Bivalent) in preventing COVID-19-related hospitalizations and outpatient visits. The findings showed that mRNA-1273.222 had greater effectiveness compared to BNT162b2 Bivalent in preventing COVID-19-related hospitalizations and outpatient visits, with increased benefits in older adults.
Article
Environmental Sciences
Yujin Han, Yawei Zhang, Sten H. Vermund
Summary: Blockchain technology, as a potential tool to address the interoperability and privacy issues of EHRs, faces challenges in data management efficiency, fairness of access, and system trust.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Menglong Li, Huichao Wu, Hongmei Yan, Jiawulan Zunong, Hongtao Hui, Hailong Li, Zhenhua Yang, Sten H. Vermund, Yifei Hu
Summary: Men who have sex with men bear a disproportionate burden of new HIV infections, and young MSM demonstrate internet-driven HIV incidents. The HIV positive prevalence and incidence were found to be higher among the social contacts of college MSM. This has implications for public health practice.