Article
Environmental Sciences
S. Descamps, S. M. Harris, J. Fluhr, P. Bustamante, Y. Cherel, A. M. Trevail, M. Brault-Favrou, S. C. Patrick
Summary: Individual heterogeneity in foraging behavior plays a crucial role in how individuals and populations respond to changes in resource availability. This study found that Antarctic petrels exhibit consistent individual differences in their diet and foraging movements at sea. Some individuals specialize in fish as prey, indicating potential resilience to changes in the marine environment.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Environmental Sciences
Kim S. Bernard, Kirsten B. Steinke, Julia M. Fontana
Summary: This study aims to understand the physiology and condition of Antarctic krill, particularly juvenile krill, during winter. The researchers found that juvenile krill maintain high respiration rates and respond positively to increased food concentrations during winter. They rely on lipid stores accumulated in summer and autumn to survive the winter. The health of juvenile krill during winter depends on their ability to accumulate lipid reserves and find sufficient food, making changes in food availability a potential issue for them.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Chemistry, Medicinal
Shuang-Yi Zhang, Guo-Xu Zhao, Shi-Kun Suo, Yu-Mei Wang, Chang-Feng Chi, Bin Wang
Summary: Fifteen antioxidant peptides were purified from Antarctic krill proteins after hydrolysis, with SLPY, QYPPMQY, and EYEA showing the highest scavenging activities and stability under various conditions.
Article
Biodiversity Conservation
Devi Veytia, Sophie Bestley, So Kawaguchi, Klaus M. Meiners, Eugene J. Murphy, Alexander D. Fraser, Kazuya Kusahara, Noriaki Kimura, Stuart Corney
Summary: Climate change affects sea ice environments, which in turn impact habitat and recruitment of polar species like Antarctic krill. Identifying sea ice characteristics as indicators of habitat quality is crucial for monitoring climate change impacts and understanding how krill populations respond to changing sea ice. The research highlights the complexity of larval dependence on sea ice and the importance of studying regional variations in sea ice influence on krill populations.
ECOLOGICAL INDICATORS
(2021)
Article
Biochemical Research Methods
Lars Moeller, Yeheven Vainstein, Lars Woehlbrand, Marvin Doerries, Bettina Meyer, Kai Sohn, Ralf Rabus
Summary: Antarctic krill utilizes hydrolytic enzymes to digest its omnivorous diet effectively, with proteome analysis revealing an abundance of proteins related to energy production and lipid degradation in the abdomen.
Article
Food Science & Technology
Peizi Sun, Xuedi Zhang, Xiang Ren, Zhiqi Cao, Yanfen Zhao, Hao Man, Dongmei Li
Summary: The effect of basic amino acid (L-arginine, L-lysine, and L-histidine) pretreatment on the quality of canned Antarctic krill was evaluated in this study. It was found that L-lysine pretreatment significantly improved the texture, water-holding capacity, color, and reduced oxidative damage of krill meat. In addition, sensory evaluation indicated that L-lysine-treated canned Antarctic krill had a better flavor and texture compared to other canned products. Overall, L-lysine shows potential as a regulatory strategy for enhancing the quality of canned Antarctic krill.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Junxin Lin, Yuying Zhang, Yiwei Li, Peizi Sun, Xiang Ren, Dongmei Li
Summary: The study demonstrated that pre-soaking with L-lysine solution improved the texture characteristics and reduced the cooking loss of Antarctic krill after heat treatment. Lysine effectively protected the structural integrity of Antarctic krill protein, enhancing its thermal stability during thermal processing.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Environmental Sciences
Wenbin Zhu, Wenbo Liu, Yuanchen Chen, Kaizhen Liao, Wenfei Yu, Hangbiao Jin
Summary: This study examined the abundance and characteristics of microplastics (MPs) in Antarctic krill samples. The results showed that MPs mainly existed in fiber form, with black, blue, and red as the predominant colors. The predominant polymer compositions were polyethylene, polypropylene, and polyester. This is the first study to investigate the occurrence of MPs in Antarctic krill samples and is important for evaluating the risks of MP exposure in Antarctic krill.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Peizi Sun, Junxin Lin, Xiang Ren, Biao Zhang, Jiaxin Liu, Yanfen Zhao, Dongmei Li
Summary: This study aimed to investigate the mechanisms underlying changes in Antarctic krill meat characteristics and physicochemical properties treated at different temperatures and holding times. The findings showed that higher temperatures and longer holding times significantly increased the hardness and cooking loss of Antarctic krill meat. The degradation of protein and transformation of structural motifs were observed, leading to the deterioration of Antarctic krill meat.
FOOD AND BIOPROCESS TECHNOLOGY
(2022)
Article
Food Science & Technology
Yue-Zhen Wang, Yu-Qin Zhao, Yu-Mei Wang, Wen-Hao Zhao, Peng Wang, Chang-Feng Chi, Bin Wang
Summary: This study aimed to purify and identify antioxidant peptides from Antarctic Krill hydrolysate and investigate their protective effects on H2O2-induced oxidative stress in Chang liver cells. Results showed that LKPGN and LQP exhibited high scavenging activities and cytoprotective effects by increasing antioxidant enzyme levels and mitochondrial membrane potential. These peptides could serve as promising candidates for health-promoting products.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Food Science & Technology
Xiang Ren, Xinyu Zhang, Peizi Sun, Junxin Lin, Yuying Zhang, Dongmei Li
Summary: This study investigated the effects of L-arginine soaking on the quality modification of heat-treated Antarctic krill. The results showed that L-arginine can improve the water-holding capacity of krill and promote the transition of myofibrillar proteins from disordered to ordered structures, ultimately improving the quality of heat-treated krill.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Junxin Lin, Peizi Sun, Yanfen Zhao, Xiaoping Du, Xiang Ren, Hao Man, Dongmei Li
Summary: L-Lys immersion pretreatment can effectively improve the quality of heat-treated Antarctic krill meat by reducing hydrophobicity and particle size, and increasing solubility. Furthermore, L-Lys intervention inhibits the aggregation behavior of myofibrillar protein and alters the structure and properties of protein.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Chemistry, Applied
Runan Sun, Xiaofang Liu, Yuan Yu, Junkui Miao, Kailiang Leng, Hua Gao
Summary: In this study, a novel peptides-zinc chelate (AKP-Zn) was obtained by reacting Antarctic krill peptides (AKP) with zinc sulfate. The structure and composition of AKP changed significantly after chelating with zinc. AKP-Zn chelate showed higher stability than zinc sulfate and zinc gluconate in various pH conditions and simulated gastrointestinal digestion experiments.
Article
Multidisciplinary Sciences
Ilenia Urso, Alberto Biscontin, Davide Corso, Cristiano Bertolucci, Chiara Romualdi, Cristiano De Pitta, Bettina Meyer, Gabriele Sales
Summary: The krill species Euphausia superba plays a critical role in the Antarctic ecosystem, but climate changes have already affected its distribution and reproductive dynamics. In this study, we identified genes involved in the krill moulting cycle, reproductive process, and sexual maturation, and discovered previously unknown differentially expressed genes related to cuticle development and energy storage. We also expanded our knowledge of the krill opsin repertoire by finding new opsin sequences. Furthermore, we created the KrillDB(2) database, which provides comprehensive information on krill genes, expression profiles, and differential expression.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Yao Zheng, Zeyu Ping, Yang Xu, Xueying Li, Quanyou Guo
Summary: The study investigates the autolysis phenomenon in Antarctic krill during buffer storage under refrigeration. The severe autolysis is more pronounced in the whole krill group compared to the tail group. The changes in visual appearance, sensory evaluation, and meat yield, as well as the hardness and shear force of the krill, demonstrate the occurrence of autolysis. The study also reveals the disrupted muscle microstructure and changes in myofibrillar protein properties and structure. Understanding the effect of autolysis on muscle stability and its protein basis in Antarctic krill is important.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Alberto Dinarello, Annachiara Tesoriere, Paolo Martini, Camilla Maria Fontana, Davide Volpato, Lorenzo Badenetti, Francesca Terrin, Nicola Facchinello, Chiara Romualdi, Oliana Carnevali, Luisa Dalla Valle, Francesco Argenton
Summary: In this study, zebrafish mutant lines and transgenic models were used to analyze the mechanism of action of glucocorticoids. The differences in gene expression patterns between different mutant lines revealed a complex network of GC-dependent transcription. The study also showed that the glucocorticoid receptor GR plays a crucial role in the transcriptional activity of Stat3, and both glucocorticoids and the mineralocorticoid receptor MR are necessary for the correct transcription of certain target genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Svenja J. Mueller, Katharina Michael, Ilenia Urso, Gabriele Sales, Cristiano De Pitta, Lavinia Suberg, Wiebke Wessels, Evgeny A. Pakhomov, Bettina Meyer
Summary: The pelagic tunicate Salpa thompsoni is an important metazoan grazer in the Southern Ocean, and its biomass and distribution have been positively correlated with ocean warming and winter sea ice decline. However, our understanding of the adaptation of S. thompsoni to the extreme seasonality of the Southern Ocean and the differences between its reproductive forms is limited.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Oncology
Angelo Velle, Chiara Pesenti, Tommaso Grassi, Luca Beltrame, Paolo Martini, Marta Jaconi, Federico Agostinis, Enrica Calura, Dionyssios Katsaros, Fulvio Borella, Robert Fruscio, Maurizio D'Incalci, Sergio Marchini, Chiara Romualdi
Summary: In this study, we investigated the expression of isomiRs in different histological subtypes of Stage I epithelial ovarian cancer (EOC) for the first time, aiming to gain new insights into their biological role in tumor growth and progression.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Multidisciplinary Sciences
Caterina Marchioretti, Giulia Zanetti, Marco Pirazzini, Gaia Gherardi, Leonardo Nogara, Roberta Andreotti, Paolo Martini, Lorenzo Marcucci, Marta Canato, Samir R. Nath, Emanuela Zuccaro, Mathilde Chivet, Cristina Mammucari, Marco Pacifici, Anna Raffaello, Rosario Rizzuto, Andrea Mattarei, Maria A. Desbats, Leonardo Salviati, Aram Megighian, Gianni Soraru, Elena Pegoraro, Elisa Belluzzi, Assunta Pozzuoli, Carlo Biz, Pietro Ruggieri, Chiara Romualdi, Andrew P. Lieberman, Gopal J. Babu, Marco Sandri, Bert Blaauw, Manuela Basso, Maria Pennuto
Summary: Marchioretti and colleagues demonstrate that there are reversible alterations in gene expression related to muscle contraction and mitochondrial respiration in the skeletal muscle of SBMA mice and patients. These alterations are accompanied by calcium accumulation inside the mitochondria, motor dysfunction, and late changes in muscle structure. The deregulation of expression of genes involved in excitation-contraction coupling (ECC) occurs with sexual maturity and androgen increase in the serum. Surgical castration and AR silencing alleviate the early and late pathological processes, indicating an androgen-dependent nature of these alterations.
NATURE COMMUNICATIONS
(2023)
Article
Cell Biology
Elena Groppa, Paolo Martini, Nima Derakhshan, Marine Theret, Morten Ritso, Lin Wei Tung, Yu Xin Wang, Hesham Soliman, Mark Stephen Hamer, Laura Stankiewicz, Christine Eisner, Le Neve Erwan, Chihkai Chang, Lin Yi, Jack H. Yuan, Sunny Kong, Curtis Weng, Josephine Adams, Lucas Chang, Anne Peng, Helen M. Blau, Chiara Romualdi, Fabio M. V. Rossi
Summary: Efficient regeneration requires coordination between multiple cell types. This study analyzes the transcriptome of hematopoietic, stromal, myogenic, and endothelial cells to understand the intercellular networks involved in regeneration. The findings identify VEGFA-driven endothelial engagement as a key differentiating feature in successful and failed regeneration models. Additionally, the study reveals that multiple cell types simultaneously produce most secreted signals, including VEGFA. Deleting VEGFA from stromal and myogenic progenitors shows that spatial compartmentalization of signaling plays a crucial role in intercellular communication networks.
Article
Cardiac & Cardiovascular Systems
Matteo Astone, Roxana E. Oberkersch, Giovanni Tosi, Alberto Biscontin, Massimo M. Santoro
Summary: This study demonstrates that endothelial cells possess an endogenous circadian clock, and core clock genes exhibit robust circadian oscillations. Impairing the function of the circadian clock transcriptional activator BMAL1 leads to angiogenesis defects in both developmental and pathological contexts. BMAL1 regulates endothelial cell cycle progression by binding to the promoters of CCNA1 and CDK1 genes.
CARDIOVASCULAR RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Changwei Shao, Shuai Sun, Kaiqiang Liu, Jiahao Wang, Shuo Li, Qun Liu, Bruce E. Deagle, Inge Seim, Alberto Biscontin, Qian Wang, Xin Liu, So Kawaguchi, Yalin Liu, Simon Jarman, Yue Wang, Hong-Yan Wang, Guodong Huang, Jiang Hu, Bo Feng, Cristiano De Pitta, Shanshan Liu, Rui Wang, Kailong Ma, Yiping Ying, Gabrielle Sales, Tao Sun, Xinliang Wang, Yaolei Zhang, Yunxia Zhao, Shanshan Pan, Xiancai Hao, Yang Wang, Jiakun Xu, Bowen Yue, Yanxu Sun, He Zhang, Mengyang Xu, Yuyan Liu, Xiaodong Jia, Jiancheng Zhu, Shufang Liu, Jue Ruan, Guojie Zhang, Huanming Yang, Xun Xu, Jun Wang, Xianyong Zhao, Bettina Meyer, Guangyi Fan
Summary: This study reveals the molecular architecture and adaptations of the Antarctic krill genome, as well as the population dynamics associated with climate change events. The findings provide valuable insights into the genetic basis of Antarctic krill's ability to survive in the Southern Ocean and offer resources for future Antarctic research.
Article
Biodiversity Conservation
Tina E. Berry, Megan L. Coghlan, Benjamin J. Saunders, Anthony J. Richardson, Matthew Power, Euan Harvey, Simon Jarman, Oliver Berry, Claire H. Davies, Michael Bunce
Summary: Using DNA metabarcoding analysis of long-term plankton samples, this study tested the ability of this method to characterize the spatial and seasonal patterns in zooplankton communities and investigate their links with abiotic data. The results demonstrate that DNA metabarcoding offers a practical approach for ecosystem-wide monitoring and understanding of marine biomes where morphological analysis is not feasible. It provides important evidence for environmental stakeholders.
DIVERSITY AND DISTRIBUTIONS
(2023)
Article
Biochemistry & Molecular Biology
Irene Zorzan, Riccardo Massimiliano Betto, Giada Rossignoli, Mattia Arboit, Andrea Drusin, Clelia Corridori, Paolo Martini, Graziano Martello
Summary: In human embryos, naive pluripotent cells of the inner cell mass (ICM) generate different cell lineages, including trophoblast cells. In vitro, chemical resetting can convert conventional pluripotent stem cells into naive pluripotent stem cells, which have the potential to efficiently generate trophoblast stem cells. This method can be used to study cell fate transitions and model placental disorders.
Article
Biochemistry & Molecular Biology
Alyssa M. Budd, Benjamin Mayne, Oliver Berry, Simon Jarman
Summary: Lifespan varies greatly among fish species, making it an important factor in species management. However, lifespan is unknown for most fish species due to difficulties in accurately identifying the oldest individuals and deriving representative estimates for the whole species.
MOLECULAR ECOLOGY RESOURCES
(2023)
Article
Genetics & Heredity
Paolo Martini, Jessica Mingardi, Giulia Carini, Stefania Mattevi, Elona Ndoj, Luca La Via, Chiara Magri, Massimo Gennarelli, Isabella Russo, Maurizio Popoli, Laura Musazzi, Alessandro Barbon
Summary: Stress is a major risk factor for psychiatric disorders, and the response to stress involves the regulation of transcriptional programs. In this study, we analyzed the gene expression changes in the prefrontal cortex (PFC) of rats exposed to acute footshock stress. We found alterations in neuronal pathways, glia development, glia-neuron networking, and synaptic function. Furthermore, specific transcription factors were identified as potential master regulators of the acute stress response.
Article
Immunology
Lorenzo Lupi, Anna Bordin, Gabriele Sales, Davide Colaianni, Adriana Vitiello, Alberto Biscontin, Alberto Reale, Alfredo Garzino-Demo, Angelo Antonini, Giancarlo Ottaviano, Carla Mucignat, Cristina Parolin, Arianna Calistri, Cristiano De Pitta
Summary: COVID-19 is a respiratory syndrome that can cause various symptoms, including deficits in smell and taste. Transcriptome analysis of olfactory mucosa revealed altered gene expression levels in patients with persistent olfactory deficits, with associations with inflammatory response and zinc homeostasis.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Biochemical Research Methods
Matteo Calgaro, Chiara Romualdi, Davide Risso, Nicola Vitulo
Summary: This article presents benchdamic, a Bioconductor package for benchmarking methods for the identification of differentially abundant taxa.