Polymorphism of Organic Cation Transporter 2 Improves Glucose-Lowering Effect of Metformin via Influencing Its Pharmacokinetics in Chinese Type 2 Diabetic Patients

Influences of Organic Cation Transporter Polymorphisms on the Population Pharmacokinetics of Metformin in Healthy Subjects

(2013) Hwa Yoon et al.   AAPS Journal

A gene–gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin

(2013) Mette M.H. Christensen et al.   Pharmacogenetics and Genomics

The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin

(2012) S L Stocker et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacogenomic association between a variant inSLC47A1gene and therapeutic response to metformin in type 2 diabetes

(2012) I. Tkáč et al.   DIABETES OBESITY & METABOLISM

SLC22A2 gene 808 G/T variant is related to plasma lactate concentration in Chinese type 2 diabetics treated with metformin

(2010) Qing Li et al.   ACTA PHARMACOLOGICA SINICA

OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine

(2010) Zhi-Jun Wang et al.   Pharmacogenetics and Genomics

Functional Characterization of the Human Organic Cation Transporter 2 Variant p.270Ala>Ser

(2009) O. Zolk et al.   DRUG METABOLISM AND DISPOSITION

Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin

(2009) Ying Chen et al.   Pharmacogenetics and Genomics

Genetic Variants of the Organic Cation Transporter 2 Influence the Disposition of Metformin

(2008) IS Song et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney

(2008) Ken Ogasawara et al.   JOURNAL OF HUMAN GENETICS

Polymorphism in human organic cation transporters and metformin action

(2008) Hiroshi Takane et al.   PHARMACOGENOMICS