Review
Oncology
Linda A. Cantwell, Emer Fahy, Emily R. Walters, Joanne M. Patterson
Summary: This systematic review examined the components and effects of nutritional prehabilitation interventions on head and neck cancer patients. The study found limited research in this area and no significant advantages of using enriched formulas in prehabilitation period.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Medicine, Research & Experimental
Corina Din-Lovinescu, Gregory L. Barinsky, Roman Povolotskiy, Jordon G. Grube, Chan W. Park
Summary: This study compared outcomes and complications in head and neck cancer (HNC) surgery patients who received a percutaneous endoscopic gastrostomy (PEG) tube on the same day of surgery versus later in hospitalization. The results showed that patients who received a PEG tube on the same day had lower complication rates, shorter length of stay, and decreased hospital costs.
Article
Health Care Sciences & Services
Yujie Wang, Qian Lu, Lichuan Zhang, Bing Zhuang, Tong Zhang, Sanli Jin, Yan Sun, Shaowen Xiao, Baomin Zheng, Yu Fang, Liqing Gong, Yanli Wang, Yiwei Cao, Weihu Wang
Summary: This study identified three NIS clusters in head and neck cancer patients undergoing CCRT, showing that the RT-specific symptom cluster was significantly associated with weight loss rate. Healthcare professionals should focus on managing multiple related symptoms, especially those in the RT-specific symptom cluster, for better patient outcomes.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Article
Nutrition & Dietetics
Zalina Abu Zaid, May Kay Neoh, Zulfitri Azuan Mat Daud, Nor Baizura Md Yusop, Zuriati Ibrahim, Zuwariah Abdul Rahman, Norshariza Jamhuri, Aishah Zafirah Abdul Azim
Summary: This study aimed to evaluate the weight loss during and post-treatment among head and neck cancer patients. The study found that the average weight loss during treatment was 7.4%, and post-treatment weight loss was 2.1%. One month after treatment completion, patients showed significant improvements in nutrition status and muscle mass, but there was a decrease in oral nutritional supplement intake.
Article
Oncology
David Forner, Florence Mok, Neil Verma, Irene Karam, David Goldstein, Kevin Higgins, Danny Enepekides, Ashlie Nadler, Robyn Pugash, Zain Husain, Kelvin Chan, Martin Smoragiewicz, Lawrence Cohen, Jeffrey W. Hazey, Eleanor C. Fung, Stephen Y. Kang, Nolan B. Seim, Colleen Simpson, Antoine Eskander
Summary: Percutaneous endoscopic gastrostomy (PEG) placement is essential for providing enteral nutrition to select head and neck cancer patients. This study found that the push technique is associated with a greater risk of developing any tube-related complication, while the pull technique may have a higher rate of stomal metastases.
Review
Oncology
Anna Edwards, Teresa Brown, Brett G. M. Hughes, Judy Bauer
Summary: This study systematically reviewed the impact of HPV status on nutritional outcomes for adult patients with oropharyngeal head and neck cancer (OPC). The findings suggest that HPV-positive patients may experience greater weight loss, higher utilization of reactive feeding tubes, and potentially lower feeding tube dependency rates compared to HPV-negative patients. However, there is uncertainty regarding differences in nutritional intake and nutritional status between the two groups. Further high-quality research is needed to improve nutritional care practices for HPV-positive patients.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Otorhinolaryngology
Tanadech Dechaphunkul, Pawitra Soonthornrak, Sarayut Lucien Geater, Arunee Dechaphunkul
Summary: This study evaluated the utilization rate of PPEG tube in head and neck cancer (HNC) patients undergoing concurrent chemoradiation (CCRT) and its impact on weight changes and tube dependence. The majority of patients used the PPEG tube, and non-users experienced greater weight loss. The fully-used group had longer time of tube dependence compared to the partially-used group. The type of PPEG tube use and the presence of dysphagia were significantly related to tube dependence.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2022)
Article
Medicine, Research & Experimental
Miroslav Vujasinovic, Elin Marsk, Apostolos Tsolakis, Boel Hynning, Martin Nordberg, Mats Lindblad, Catarina Lindqvist, Lalle H. Nordenvall, Rusana Bark, Peter Elbe
Summary: This study aimed to determine the complication rates after percutaneous endoscopic gastrostomy (PEG) and open gastrostomy (OG) in patients with head and neck cancers (HNCs). The results showed that enteral feeding via gastrostomy is a safe method, regardless of the technique used (PEG or OG), with a low rate of major complications and no mortality linked to the procedure.
Article
Otorhinolaryngology
Taru Ilmarinen, Lalle Hammarstedt-Nordenvall, Leif Back, Antti Makitie
Summary: The study assessed policies and perceptions of enteral tube feeding in head and neck cancer patients undergoing chemoradiotherapy in the Nordic countries. Results showed variations in enteral tube feeding practices within and between the Nordic countries. Unified protocols for tube feeding should be developed for this patient population to ensure consistency and optimal care.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Oncology
Niharika Bisht, Sankalp Singh, Arti Sarin, Amul Kapoor, Samir Gupta, Deepak Mulajker, Richa Joshi
Summary: This retrospective study aimed to assess weight loss in head and neck cancer patients undergoing chemoradiotherapy, finding that nutritional impairment is an important factor affecting morbidity and possibly mortality, but no specific factors were found to be significantly associated with weight loss. More robust studies are needed to identify factors affecting weight loss and whether it can be used as a prognostic parameter for patients.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2021)
Article
Nutrition & Dietetics
Qing-Qing Xu, Lan-Lan Guo, Jia-Hao Lou, Liu Chen, Ying Wang, Lei Chen, Li-Xia Lu
Summary: This study aimed to compare the clinical outcomes, quality of life, and complication rates of prophylactic percutaneous endoscopic gastrostomy (pPEG) tube, reactive percutaneous endoscopic gastrostomy (rPEG) tube, and reactive nasogastric tube (rNGT) insertion in patients with head and neck cancers. The results showed that prophylactic pPEG could improve nutrition outcomes, reduce treatment delay, and maintain a good quality of life.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Biology
Tzu-Ting Huang, Shang-Yu Chou, Yun-Hsuan Lin, Shau-Hsuan Li, Yen-Hao Chen, Hung- Lu, Chien-Ming Lo, Fu-Min Fang, Yi-Chun Chiu, Yeh-Pin Chou, Yu-Ming Wang
Summary: Weight loss during definitive chemoradiotherapy can serve as a prognostic factor for unresectable esophageal cancer patients. In this study, a weight loss of 4% or less was associated with superior overall survival in cT4b patients.
Review
Nutrition & Dietetics
Maurizio Bossola, Manuela Antocicco, Gilda Pepe
Summary: Patients with head and neck cancer often suffer from malnutrition before diagnosis and treatment. Chemoradiotherapy can worsen their symptoms and worsen malnutrition. Nasogastric tubes and percutaneous endoscopic gastrostomy are used for enteral nutrition when cancer and/or mucositis interfere with swallowing. Studying the nutrition outcomes, survival, hospitalizations, radiotherapy interruptions, quality of life, and swallowing function, comparing NGT and PEG, the analysis finds that they have similar outcomes in nutrition, survival, and quality of life, while swallowing function seems to be better with NGT. PEG may have more complications and higher costs. Prophylactic feeding through NGT or PEG does not offer significant advantages over reactive feeding.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Otorhinolaryngology
Claudio Sampieri, Andrea Costantino, Giorgio Gregory Giordano, Michael Dale, Filippo Marchi, Andrea Iandelli, Marta Filauro, Giampiero Parrinello, Gian Marco Pace, Bianca Maria Festa, Giuseppe Spriano, Armando De Virgilio, Giorgio Peretti
Summary: The study developed a prediction model using a scoring system and nomogram to predict the necessity of enteral nutrition for head and neck surgery patients at 28 days postoperatively. The model showed high prediction performances and can guide the development of personalized nutrition protocols.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Nutrition & Dietetics
Diogo Sousa-Catita, Claudia Ferreira-Santos, Paulo Mascarenhas, Catia Oliveira, Raquel Madeira, Carla Adriana Santos, Carla Andre, Catarina Godinho, Luis Antunes, Jorge Fonseca
Summary: This retrospective study evaluated risk markers of poor outcomes in percutaneous endoscopic gastrostomy (PEG)-fed head and neck cancer (HNC) patients. The study analyzed TNM-defined stages, initial anthropometry, and laboratory data. The results showed that advanced cancer stages and low parameters were associated with poor outcomes. Initial MAMC and PEG duration were significant determinants of survival, highlighting the importance of preserving muscle mass and early gastrostomy. The study provides important insights for supporting PEG-fed HNC patients.