Article
Multidisciplinary Sciences
Dong-Joo Shin, Hongyoon Choi, Dong Kyu Oh, Hyun Pil Sung, Jun-Hyeong Kim, Dong-Hyun Kim, Soo-Yeon Kim
Summary: This study investigated the correlation between SUV of F-18-FDG PET/CT and conductivity parameters in breast cancer. The results showed a low positive correlation between SUVpeak and mean conductivity in breast cancer, suggesting that conductivity has the potential to be a noninvasive predictor of lymphovascular invasion (LVI) status.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Mohammad N. Hosni, Mutaz Kassas, Mohamad I. Itani, Mahmoud A. Rahal, Safaa Al-Zakleet, Malak El-Jebai, Alain S. Abi-Ghanem, Hicham Moukaddam, Mohamad Haidar, Sobhan Vinjamuri, Yasser H. Shaib
Summary: Incidental gastrointestinal tract (GIT) [18F]-Fluorodeoxyglucose (FDG) uptake in positron emission technology/computed tomography (PET/CT) is a complex finding. This retrospective study reviewed 8991 charts of patients who underwent PET/CT, and found that patients with cancer/pre-cancer lesions were older and had lower GIT uptake. Patients with focal and lower GIT uptake had a higher likelihood of cancer/pre-cancerous lesions. An SUVmax of 9.2 had the highest sensitivity and specificity in detecting these lesions.
Article
Computer Science, Artificial Intelligence
Valentin Oreiller, Vincent Andrearczyk, Mario Jreige, Sarah Boughdad, Hesham Elhalawani, Joel Castelli, Martin Vallieres, Simeng Zhu, Juanying Xie, Ying Peng, Andrei Iantsen, Mathieu Hatt, Yading Yuan, Jun Ma, Xiaoping Yang, Chinmay Rao, Suraj Pai, Kanchan Ghimire, Xue Feng, Mohamed A. Naser, Clifton D. Fuller, Fereshteh Yousefirizi, Arman Rahmim, Huai Chen, Lisheng Wang, John O. Prior, Adrien Depeursinge
Summary: This paper presents the post-analysis of the first edition of the HEad and neCK TumOR (HECKTOR) challenge, which focused on automatic segmentation of head and neck tumors in combined FDG-PET and CT images. A total of 64 teams participated in the challenge, and the best method achieved a high Dice Score Coefficient (DSC) and outperformed human inter-observer agreement and other methods.
MEDICAL IMAGE ANALYSIS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Simone Wegen, Lutz van Heek, Philipp Linde, Karina Claus, Dennis Akuamoa-Boateng, Christian Baues, Shachi Jenny Sharma, Klaus Schomaecker, Thomas Fischer, Katrin Sabine Roth, Jens Peter Klussmann, Simone Marnitz, Alexander Drzezga, Carsten Kobe
Summary: This study compares the use of [(68) Ga]Ga-FAPI-46 PET/CT and [F-18]F-FDG PET/CT in improving target volume definition and radiotherapy planning for head and neck cancers. The results demonstrate the usefulness of [(68) Ga]Ga-FAPI-46 PET/CT in detecting tumor lesions in these patients.
MOLECULAR IMAGING AND BIOLOGY
(2022)
Article
Oncology
Beat Bojaxhiu, Dubravko Sinovcic, Olgun Elicin, Arnoud J. Templeton, Mohamed Shelan, Jan Wartenberg, Ian Alberts, Axel Rominger, Daniel M. Aebersold, Kathrin Zaugg
Summary: This study evaluated the correlation between markers of host inflammation and FDG-PET/CT metabolic parameters. The results showed that platelet-to-lymphocyte ratio was associated with tumor metabolic volume and total lesion glycolysis, while systemic inflammation was not correlated with FDG-PET/CT parameters.
RADIATION ONCOLOGY
(2022)
Article
Oncology
Austin J. Iovoli, Mark K. Farrugia, Sung Jun Ma, Jon M. Chan, Michael R. Markiewicz, Ryan McSpadden, Kimberly E. Wooten, Vishal Gupta, Moni A. Kuriakose, Wesley L. Hicks, Anurag K. Singh
Summary: Repeat PET/CT imaging can provide valuable information for head and neck cancer patients in assessing treatment response, reducing the incidence of unnecessary biopsies and surgeries, and preventing treatment failure.
Article
Computer Science, Information Systems
Wenbing Lv, Hui Feng, Dongyang Du, Jianhua Ma, Lijun Lu
Summary: This study investigated the prognostic value of peri-tumoral radiomics features of pre-treatment PET/CT images in patients with head and neck cancer. The integration of intra-tumoral and peri-tumoral radiomics features showed better performance than either of them alone, with peri-tumoral regions closer to the intra-tumoral region demonstrating better performance.
Article
Computer Science, Interdisciplinary Applications
Yiling Wang, Elia Lombardo, Michele Avanzo, Sebastian Zschaek, Julian Weingaertner, Adrien Holzgreve, Nathalie L. Albert, Sebastian Marschner, Giuseppe Fanetti, Giovanni Franchin, Joseph Stancanello, Franziska Walter, Stefanie Corradini, Maximilian Niyazi, Jinyi Lang, Claus Belka, Marco Riboldi, Christopher Kurz, Guillaume Landry
Summary: This study aimed to achieve prognosis for distant metastasis and overall survival in head and neck cancer patients using deep learning models, and investigate the predictive performance of combined PET/CT compared to single-modality inputs. The results showed that the PET-only model achieved the best predictive performance, suggesting that GTV segmentation may be less relevant for PET-based prognosis.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ahmed Ragab, Jianrong Wu, Xue Ding, Aurela Clark, Blaine Mischen, Aman Chauhan, M. Elizabeth Oates, Lowell Anthony, Riham El Khouli
Summary: The study found that SUL is a more reproducible and less variable quantitative measure in DOTA PET/CT scans compared to SUVbw. Among organs with physiological uptake, liver SUL is identified as the optimal internal reference due to its larger size and uniform SUL values resulting in lower variability and better reproducibility.
ACADEMIC RADIOLOGY
(2022)
Review
Oncology
Richard H. Wiggins, John M. Hoffman, Gabriel C. Fine, Matthew F. Covington, Ahmed Ebada Salem, Bhasker R. Koppula, Kathryn A. Morton
Summary: PET-CT is an advanced imaging technique widely used in oncology for staging, therapeutic response assessment, restaging, and surveillance of tumors. This review article is part of a series of six articles that provide an overview of the value, applications, and interpretive strategies of PET-CT in common adult malignancies. The fifth article in the series focuses on PET-CT imaging in head and neck tumors and neuro oncology.
Article
Multidisciplinary Sciences
Soeun Park, Eun-Ki Min, Soong June Bae, Chihwan Cha, Dooreh Kim, Janghee Lee, Yoon Jin Cha, Sung Gwe Ahn, Joon Jeong
Summary: The study found an association between SUV values and stromal TIL levels in breast cancer, with tumors having high SUVmax showing higher TIL levels. SUVmax was identified as an independent factor linked to high TIL levels.
SCIENTIFIC REPORTS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Louise M. Risor, Malene M. Clausen, Zaza Ujmajuridze, Mohammed Farhadi, Kim F. Andersen, Annika Loft, Jeppe Friborg, Andreas Kjaer
Summary: The study aimed to evaluate the prognostic value of uPAR PET/CT and compare it with F-18-FDG in head and neck cancer patients. The results showed promising results for the use of Ga-68-uPAR PET SUVmax in predicting relapse-free survival in these patients.
JOURNAL OF NUCLEAR MEDICINE
(2022)
Article
Oncology
C. Pisani, L. Vigna, F. Mastroleo, G. Loi, V Amisano, L. Masini, L. Deantonio, P. Aluffi Valletti, G. Sacchetti, M. Krengli
Summary: The study analyzed the pattern of failure in head and neck squamous cell carcinoma patients treated with definitive radio-chemotherapy in relation to pre-treatment [F-18] FDG-PET/CT uptake. The research findings suggest that tumor recurrence in high-dose volume may be a potential indicator for local relapse prevention by intensifying the dose on these volumes.
RADIATION ONCOLOGY
(2021)
Article
Otorhinolaryngology
Brendan C. Stack, Fenghai Duan, Rathan M. Subramaniam, Justin Romanoff, JoRean D. Sicks, Twyla Bartel, Chien Chen, Val J. Lowe
Summary: FDG-PET/CT is effective for assessing neck nodal disease. This study reports the risks and patterns of nodal disease based on primary site and nodal level, with oral cavity (level I), pharynx (level II), and larynx (level VI) being the levels at greatest risk for nodal disease in cN0.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Ludwig Opalinski, Sandra Schmitz, Pascal Van Eeckhout, Philippe d'Abadie, Olivier Gheysens
Summary: A 54-year-old man with a history of tonsillar squamous cell carcinoma and seropositive rheumatoid arthritis presented with right cervical pain and dysphagia. Imaging showed a necrotic lesion connected to the hyoid bone. Surgical resection revealed a necrotizing granuloma consistent with a rheumatoid nodule.
CLINICAL NUCLEAR MEDICINE
(2023)