期刊
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
卷 90, 期 1, 页码 21-27出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijpsycho.2012.09.011
关键词
Psychological stress; Stress reactivity; Blood pressure; Heart rate; Cortisol
资金
- European Union [279281]
- Netherlands Heart Foundation [NHS2007B083]
- European Science Foundation (Eurostress)
- Netherlands Organization for Scientific Research
The Dutch Famine Birth Cohort Study is a large population based study of late middle aged, overall healthy men and women whose health has been followed from 50 to 65 years of age. In a sample of 725 cohort members, an extensive psychological stress protocol was performed during which cardiovascular and cortisol responses were measured. In line with many previous studies, results showed that increased blood pressure responsiveness to the stress protocol was associated with an increased risk for hypertension 5 years later. However, decreased cardiovascular and/or cortisol stress reactivity were associated with obesity and the risk of becoming obese, symptoms of depression and anxiety, a poor self-reported health, poor lung function, and poor cognitive function (all p for statistical tests <0.05). These associations generally survived adjustment for a range of potential confounders, including resting cardiovascular and cortisol activity, commitment to the stress tasks, sex, age, smoking and use of medication. Results from these studies agree with recent evidence that low biological reactivity to acute psychological stress may not always be beneficial for health but instead seems to be a marker for a range of negative health outcomes. Future studies have to point out whether low stress reactivity precedes or follows these negative health outcomes. (C) 2012 Elsevier B.V. All rights reserved.
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