A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expression

Serine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer

(2015) Liang Hu et al.   BMC CANCER

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Regulation of cell proliferation and migration by p62 through stabilization of Twist1

(2014) L. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bladder Polypoid Cystitis-Derived A20 Associates with Tumorigenesis

(2013) Ming Wang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The Prognostic Significance and Therapeutic Potential of Hedgehog Signaling in Intrahepatic Cholangiocellular Carcinoma

(2013) L. Tang et al.   CLINICAL CANCER RESEARCH

MUC15 Inhibits Dimerization of EGFR and PI3K–AKT Signaling and Is Associated With Aggressive Hepatocellular Carcinomas in Patients

(2013) Ruo–Yu Wang et al.   GASTROENTEROLOGY

A20 (TNFAIP3) Deletion in Epstein-Barr Virus-Associated Lymphoproliferative Disorders/Lymphomas

(2013) Midori Ando et al.   PLoS One

NF-κB Regulates Mesenchymal Transition for the Induction of Non-Small Cell Lung Cancer Initiating Cells

(2013) Manish Kumar et al.   PLoS One

Twist1 Promotes Gastric Cancer Cell Proliferation through Up-Regulation of FoxM1

(2013) Jianxin Qian et al.   PLoS One

Twist: a molecular target in cancer therapeutics

(2013) Md. Asaduzzaman Khan et al.   TUMOR BIOLOGY

Targeting A20 enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells

(2012) Bingfei Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epithelial-Mesenchymal Transition Induced by TNF-  Requires NF- B-Mediated Transcriptional Upregulation of Twist1

(2012) C.-W. Li et al.   CANCER RESEARCH

TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells

(2012) M. B. Weiss et al.   CANCER RESEARCH

A20 promotes liver regeneration by decreasing SOCS3 expression to enhance IL-6/STAT3 proliferative signals

(2012) Cleide G. da Silva et al.   HEPATOLOGY

Expression of A20 is reduced in pancreatic cancer tissues

(2012) Qing Wang et al.   JOURNAL OF MOLECULAR HISTOLOGY

A20 Ubiquitin Ligase–Mediated Polyubiquitination of RIP1 Inhibits Caspase-8 Cleavage and TRAIL-Induced Apoptosis in Glioblastoma

(2012) Anita C. Bellail et al.   Cancer Discovery

Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms

(2011) Qian Qin et al.   CELL RESEARCH

Tumor suppressor TNFAIP3 (A20) is frequently deleted in Sézary syndrome

(2011) F C M Braun et al.   LEUKEMIA

HBx Sensitizes Cells to Oxidative Stress-induced Apoptosis by Accelerating the Loss of Mcl-1 Protein via Caspase-3 Cascade

(2011) Liang Hu et al.   Molecular Cancer

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Activator protein-1 involvement in proliferation inhibition by gene silencing of Twist in gastric cancer cells

(2011) Geng-Qiu Luo et al.   PATHOLOGY

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathways

(2010) Jing Fu et al.   HEPATOLOGY

Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1

(2010) Xiu-lan Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

(2010) N. Shembade et al.   SCIENCE

Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth

(2010) Anita B. Hjelmeland et al.   PLOS BIOLOGY

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

(2009) K. Honma et al.   BLOOD

Sphingosine Kinase 1 Is Associated with Gastric Cancer Progression and Poor Survival of Patients

(2009) W. Li et al.   CLINICAL CANCER RESEARCH

A20 is overexpressed in glioma cells and may serve as a potential therapeutic target

(2009) Qingdong Guo et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

TNFAIP3(A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

(2009) Roland Schmitz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NF-κB and cancer: how intimate is this relationship

(2009) Sahdeo Prasad et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

NF- B as a Critical Link Between Inflammation and Cancer

(2009) M. Karin   Cold Spring Harbor Perspectives in Biology

NF-kappa B genes have a major role in Inflammatory Breast Cancer

(2008) Florence Lerebours et al.   BMC CANCER

Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

(2007) Su-Chang Lin et al.   JOURNAL OF MOLECULAR BIOLOGY