Article
Biochemistry & Molecular Biology
Gatta K. R. S. Naresh, Lalitha Guruprasad
Summary: The active and inactive conformations of kinases are crucial for the activation of downstream signaling pathways. Molecular dynamics simulations provide insights into the structural alterations of kinases that contribute to cellular activities and signaling pathways. This study focuses on the TAM receptor tyrosine kinases and their interaction with cabozantinib, revealing the dynamic pathways and structural changes induced by the inhibitor.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Astronomy & Astrophysics
Patrick Fraser
Summary: In this paper, the fluctuations of Gaussian states in LQC are derived, showing that they diverge as the state variance increases contrary to ordinary quantum mechanics. However, by scaling the holonomy length with a volume regularization parameter, these fluctuations can be arbitrarily suppressed.
Article
Optics
Jun Xu, Fei Wang
Summary: Strong nonlinearities in microwave-modified EIT systems can achieve perfect higher-order squeezing, where the nonlinearity is closely related to the squeezing parameter and dissipative rate. Under ideal conditions, the two-mode higher-order squeezing can reach nearly 100% effectiveness.
Article
Health Care Sciences & Services
Madeline Smith-Johnson
Summary: This study reveals that transgender adults have a higher probability of reporting disabilities compared to their cisgender peers in the US. The adjusted probabilities show that transgender adults have a 27% chance of having at least one disability at age twenty and a 39% chance at age fifty-five, nearly twice the rate of their cisgender counterparts at both ages. The findings underscore the importance of considering disability from a life-course perspective, the impact of intersectional identities on disability risk, and the urgency of targeted health interventions for transgender individuals in the US.
Article
Ecology
Petr Sklenar, Ricardo Jaramillo, Susanne Sivila Wojtasiak, Rosa Isela Meneses, Priscilla Muriel, Adam Klimes
Summary: The tolerance of species to extreme temperatures determines their distribution and vulnerability to climate change. This study compared the thermal tolerance of tropical and temperate alpine plants and found that there were no significant differences in temperature resistance between the two groups. The hypotheses tested did not hold true, indicating that temperature tolerance breadth and resistance to frost and heat do not vary significantly between temperate and tropical plants.
GLOBAL ECOLOGY AND BIOGEOGRAPHY
(2023)
Article
Psychology, Multidisciplinary
Manon Schutter, Eric van Dijk, Erik W. de Kwaadsteniet, Wilco W. van Dijk
Summary: The research found that reactions to not being trusted are significantly affected by whether the decision is active or inactive. Active decisions lead to more negative evaluations and emotions, reducing satisfaction with the final outcome.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Materials Science, Multidisciplinary
P. A. Igoshev, A. A. Katanin
Summary: We use the functional renormalization group technique with temperature as a scale parameter to investigate the possibility of ferromagnetic ordering in the nondegenerate Hubbard model on the face-centered cubic lattice. By assuming the relations between hopping parameters, we find that ferromagnetic instability forms with decreasing temperature. We calculate the phase diagrams of chemical potential versus temperature and find that ferromagnetic order only occurs when the density of states diverges and the fillings are near the van Hove singularity. The obtained Curie temperature is significantly smaller compared to the results of the random-phase approximation.
Article
Cell Biology
Rebecca E. O'Connor, Lucas G. Kiazim, Claudia C. Rathje, Rebecca L. Jennings, Darren K. Griffin
Summary: Pigs are the world's leading source of meat protein, but hypoprolific boars may incur significant economic and environmental losses. Reciprocal translocations are a leading cause of porcine hypoprolificacy, which may be significantly under-reported using traditional karyotyping. A multiple hybridisation fluorescence in situ hybridisation strategy can detect translocations, highlighting the importance of pre-emptive screening before boars enter breeding programs.
Article
Chemistry, Physical
Haneul Kim, Joonwoo Kim, Ja Hun Kwak
Summary: In this study, it is shown that the weak interaction of CO with Pt/TiO2 under the CO oxidation condition is the reason for the higher CO oxidation activity of Pt/rutile compared to Pt/anatase. The CO temperature-programmed desorption (TPD) and in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) results indicate that the onset temperatures of CO desorption on freshly prepared Pt/rutile and Pt/anatase are the same. However, after the reaction test, the CO-TPD curves for Pt/rutile show a shift in the desorption temperature to a lower temperature, while Pt/anatase does not change. In situ pulse reaction using DRIFTS reveals that CO on Pt/rutile reacts with oxygen faster than CO on Pt/anatase. IR spectra with peak deconvolution of adsorbed CO on Pt/rutile show that CO adsorbed on the terrace sites of Pt clusters on rutile readily reacts with O2. These results indicate that the higher low-temperature activity of Pt/rutile is due to its weaker interaction with CO compared to Pt/anatase under the reaction conditions. Our findings deepen the fundamental understanding of metal-support interaction and CO oxidation on Pt/TiO2 catalysts.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Polymer Science
Takahiro Ishida, Taichi Sotani, Natsuhiro Sano, Hiromitsu Sogawa, Fumio Sanda
Summary: This study demonstrates the chirality transfer from optically active diphosphine ligands to optically inactive platinum-containing polymers. The reaction produces different platinum complexes, with one polymer showing unique solubility and a folded helical conformation.
Article
Physiology
Raphael Bertschinger, Louis-Solal Giboin, Markus Gruber
Summary: The study found that cyclists did not exhibit higher Hoffmann reflexes compared to recreationally active controls, despite significant differences in endurance performance. Cyclists showed a steeper slope in the muscle M recruitment curve, indicating that the training-specific sensorimotor control of endurance sports may affect spinal motoneurons differently on Ia-afferent inputs.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biodiversity Conservation
Xiaojuan Huang, Yue Liu, Yiming Cong, Yuwen Zhang, Xinzhou Zhao, Ling Huang, Qiqi Li, Lan Li, Fujiang Hou
Summary: Soil moisture is influenced by land use type, precipitation, heat, and human activity. The response of soil moisture to annual precipitation and temperature varies among different land use types. Cropland has higher water use and lower water use efficiency compared to rangeland. The mean annual water deficiencies for cropland, rangeland, and woodland are 42.41 mm, 21.38 mm, and 15.49 mm, respectively. Human activity in land use types increases with precipitation, with cropland being the most sensitive and rangeland being insensitive. The productivity of rangeland and cropland is stabilized by increasing resistance and resilience to soil moisture, respectively.
ECOLOGICAL INDICATORS
(2022)
Article
Materials Science, Multidisciplinary
Tong Wang, Zhiming Pan, Keith Slevin, Tomi Ohtsuki
Summary: Disorder is widely present in solid-state systems and its influence on transport properties has been revealed by the discovery of Anderson localization. The study of Anderson transition relies on scaling theory and symmetry classes, with a particular interest in the critical exponent nu characterizing the power-law divergence of localization length. While the lower critical dimension dl = 2 of Anderson transition is well-established, the upper critical dimension du remains uncertain and precise numerical evaluations of the critical exponent in higher dimensions are needed. This study estimates the critical exponents of Bogoliubov-de Gennes classes using the Borel-Pade resummation method and compares the results with numerical simulations and previously published work.
Article
Medicine, General & Internal
Bo Yang, Yu Zhao, Yangxue Zhao
Summary: The incidence of fracture between sandwich vertebra and ordinary adjacent vertebra after PKP was compared, and it was found that the incidence of sandwich vertebral fracture was not higher than that of ordinary adjacent vertebral fractures.
Article
Orthopedics
Sun-Ho Lee, Hyoung-Yeon Seo, Jun-Hyuk Lim, Min-Gwang Kim, Jong-Keun Seon
Summary: This study found that patients undergoing TKA after UKA or HTO had higher revision rates compared to those undergoing primary TKA, with HTO patients having lower revision risk than UKA patients. However, no significant differences in postoperative complications were found between the two groups.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2021)