Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells

EGFR Tyrosine 845 Phosphorylation-Dependent Proliferation and Transformation of Breast Cancer Cells Require Activation of p38 MAPK

(2014) Kelly L. Mueller et al.   Translational Oncology

Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topology

(2013) Tapesh Santra et al.   BMC Systems Biology

Model-Based Analysis of HER Activation in Cells Co-Expressing EGFR, HER2 and HER3

(2013) Harish Shankaran et al.   PLoS Computational Biology

Roles of p38 MAPKs in invasion and metastasis

(2012) Ivan del Barco Barrantes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance

(2012) Edita Aksamitiene et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models

(2012) Fulvio Chiacchiera et al.   CANCER LETTERS

Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer

(2012) M. Sen et al.   CLINICAL CANCER RESEARCH

Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics

(2012) Harish Shankaran et al.   Molecular BioSystems

Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome Gefitinib-resistance in non-small cell lung cancer cell lines

(2011) H Li et al.   Advances in Medical Sciences

Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells

(2011) Nicole Grabinski et al.   CELLULAR SIGNALLING

A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network

(2011) Shannon E. Telesco et al.   Molecular BioSystems

An ErbB3 Antibody, MM-121, Is Active in Cancers with Ligand-Dependent Activation

(2010) B. Schoeberl et al.   CANCER RESEARCH

Kinase-mediated quasi-dimers of EGFR

(2010) Erez M. Bublil et al.   FASEB JOURNAL

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

(2010) Fumin Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells

(2009) Yi Zhang et al.   BMC CELL BIOLOGY

Cancer systems biology: a network modeling perspective

(2009) P. K. Kreeger et al.   CARCINOGENESIS

Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

(2009) N. Jura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor-PI3K Axis

(2009) B. Schoeberl et al.   Science Signaling

Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking

(2008) Harish Shankaran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

System theoretical investigation of human epidermal growth factor receptor-mediated signalling

(2008) Y. Zhang et al.   IET Systems Biology

Multiple Mechanisms Are Responsible for Transactivation of the Epidermal Growth Factor Receptor in Mammary Epithelial Cells

(2008) Karin D. Rodland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multipathway Model Enables Prediction of Kinase Inhibitor Cross-Talk Effects on Migration of Her2-Overexpressing Mammary Epithelial Cells

(2008) N. Kumar et al.   MOLECULAR PHARMACOLOGY

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL