Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis
出版年份 2015 全文链接
标题
Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis
作者
关键词
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出版物
MOLECULAR BIOLOGY OF THE CELL
Volume 26, Issue 16, Pages 2927-2938
出版商
American Society for Cell Biology (ASCB)
发表日期
2015-06-25
DOI
10.1091/mbc.e15-03-0159
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage
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- Biogenesis of the multifunctional lipid droplet: Lipids, proteins, and sites
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- Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease
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- Balancing the fat: lipid droplets and human disease
- (2013) Natalie Krahmer et al. EMBO Molecular Medicine
- Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains
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- Phosphatidylcholine and the CDP–choline cycle
- (2012) Paolo Fagone et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- ras-induced Up-regulation of CTP:Phosphocholine Cytidylyltransferase α Contributes to Malignant Transformation of Intestinal Epithelial Cells
- (2012) Daniel J. Arsenault et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal
- (2012) Marianna Agassandian et al. MOLECULAR BIOLOGY OF THE CELL
- CTP:phosphocholine cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure without affecting phosphatidylcholine synthesis
- (2011) Karsten Gehrig et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase
- (2011) Natalie Krahmer et al. Cell Metabolism
- Human Lysophosphatidylcholine Acyltransferases 1 and 2 Are Located in Lipid Droplets Where They Catalyze the Formation of Phosphatidylcholine
- (2011) Christine Moessinger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture andin Vivo
- (2011) Gerd Hörl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 14-3-3ζ escorts CCTα for calcium-activated nuclear import in lung epithelia
- (2009) Marianna Agassandian et al. FASEB JOURNAL
- Masking of a Nuclear Signal Motif by Monoubiquitination Leads to Mislocalization and Degradation of the Regulatory Enzyme Cytidylyltransferase
- (2009) B. B. Chen et al. MOLECULAR AND CELLULAR BIOLOGY
- Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain
- (2008) Karsten Gehrig et al. JOURNAL OF LIPID RESEARCH
- Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
- (2008) Yi Guo et al. NATURE
- Expansion of the Nucleoplasmic Reticulum Requires the Coordinated Activity of Lamins and CTP:Phosphocholine Cytidylyltransferase α
- (2007) Karsten Gehrig et al. MOLECULAR BIOLOGY OF THE CELL
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