The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting

Novel insights into G protein and G protein-coupled receptor signaling in cancer

(2014) Morgan O’Hayre et al.   CURRENT OPINION IN CELL BIOLOGY

The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4

(2014) Justine Holleman et al.   MOLECULAR BIOLOGY OF THE CELL

The Yeast Alix Homolog Bro1 Functions as a Ubiquitin Receptor for Protein Sorting into Multivesicular Endosomes

(2013) Natasha Pashkova et al.   DEVELOPMENTAL CELL

Viral Infection Controlled by a Calcium-Dependent Lipid-Binding Module in ALIX

(2013) Christin Bissig et al.   DEVELOPMENTAL CELL

Structure-based in silico identification of ubiquitin-binding domains provides insights into the ALIX-V:ubiquitin complex and retrovirus budding

(2013) Tal Keren-Kaplan et al.   EMBO JOURNAL

Transactivation of the PAR1-PAR2 Heterodimer by Thrombin Elicits β-Arrestin-mediated Endosomal Signaling

(2013) Huilan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin conjugation to Gag is essential for ESCRT-mediated HIV-1 budding

(2013) Paola Sette et al.   Retrovirology

Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling

(2012) Adriano Marchese et al.   CELLULAR SIGNALLING

Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking

(2012) Sang-Oh Han et al.   EMBO REPORTS

ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting

(2012) Michael R. Dores et al.   JOURNAL OF CELL BIOLOGY

AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway

(2012) Michael R. Dores et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian Alpha Arrestins Link Activated Seven Transmembrane Receptors to Nedd4 Family E3 Ubiquitin Ligases and Interact with Beta Arrestins

(2012) Fortune F. Shea et al.   PLoS One

New insights from structural biology into the druggability of G protein-coupled receptors

(2012) Jonathan S. Mason et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Adaptor Protein Complex-2 (AP-2) and Epsin-1 Mediate Protease-activated Receptor-1 Internalization via Phosphorylation- and Ubiquitination-dependent Sorting Signals

(2011) Buxin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through  -arrestin and dishevelled-2 scaffolds

(2011) U. J. K. Soh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the β2-adrenergic receptor

(2010) Joseph F Nabhan et al.   EMBO REPORTS

AMSH Interacts with ESCRT-0 to Regulate the Stability and Trafficking of CXCR4

(2010) Maria I. Sierra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ESCRT-Associated Protein Alix Recruits the Ubiquitin Ligase Nedd4-1 To Facilitate HIV-1 Release through the LYPXnL L Domain Motif

(2010) P. Sette et al.   JOURNAL OF VIROLOGY

Multiple Interactions between the ESCRT Machinery and Arrestin-Related Proteins: Implications for PPXY-Dependent Budding

(2010) S. Rauch et al.   JOURNAL OF VIROLOGY

Arrestin-2 Interacts with the Endosomal Sorting Complex Required for Transport Machinery to Modulate Endosomal Sorting of CXCR4

(2010) Rohit Malik et al.   MOLECULAR BIOLOGY OF THE CELL

The Role of Ubiquitination in Lysosomal Trafficking of δ-Opioid Receptors

(2010) Anastasia G. Henry et al.   TRAFFIC

Endosomal Deubiquitinating Enzymes Control Ubiquitination and Down-regulation of Protease-activated Receptor 2

(2009) Burcu Hasdemir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Protease-activated Receptor-2 Differentially Regulates Desensitization and Internalization

(2009) Tiffany K. Ricks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Crescent-Shaped ALIX Dimer Targets ESCRT-III CHMP4 Filaments

(2009) Ricardo Pires et al.   STRUCTURE

Agonist-dependent internalization and trafficking of the human prostacyclin receptor: A direct role for Rab5a GTPase

(2008) Martina B. O'Keeffe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

On the origins of arrestin and rhodopsin

(2008) Carlos E Alvarez   BMC EVOLUTIONARY BIOLOGY

Nedd4 Mediates Agonist-dependent Ubiquitination, Lysosomal Targeting, and Degradation of the β2-Adrenergic Receptor

(2008) Sudha K. Shenoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ALIX-CHMP4 interactions in the human ESCRT pathway

(2008) J. McCullough et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes

(2007) Adriano Marchese et al.   Annual Review of Pharmacology and Toxicology