Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis

(2013) Peter E. Czabotar et al.   CELL

Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis

(2013) D Westphal et al.   CELL DEATH AND DIFFERENTIATION

The rheostat in the membrane: BCL-2 family proteins and apoptosis

(2013) N Volkmann et al.   CELL DEATH AND DIFFERENTIATION

The retinoblastoma protein induces apoptosis directly at the mitochondria

(2013) K. I. Hilgendorf et al.   GENES & DEVELOPMENT

Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size

(2013) Stephanie Bleicken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BID-induced structural changes in BAK promote apoptosis

(2013) Tudor Moldoveanu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Three-dimensional structure of Bax-mediated pores in membrane bilayers

(2013) X-P Xu et al.   Cell Death & Disease

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

(2012) Jerry E. Chipuk et al.   CELL

Single vs. swarm detection of microparticles and exosomes by flow cytometry

(2012) E. Van Der POL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Bax Activation Initiates the Assembly of a Multimeric Catalyst that Facilitates Bax Pore Formation in Mitochondrial Outer Membranes

(2012) Yulia Kushnareva et al.   PLOS BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Reconstitution of Proapoptotic BAK Function in Liposomes Reveals a Dual Role for Mitochondrial Lipids in the BAK-driven Membrane Permeabilization Process

(2011) Olatz Landeta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria

(2011) Fabien Llambi et al.   MOLECULAR CELL

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

Photoreactive Stapled BH3 Peptides to Dissect the BCL-2 Family Interactome

(2010) Craig R. Braun et al.   CHEMISTRY & BIOLOGY

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Molecular Details of Bax Activation, Oligomerization, and Membrane Insertion

(2009) Stephanie Bleicken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of the Mitochondrial Apoptosis-induced Channel, MAC

(2009) Sonia Martinez-Caballero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

(2009) G. Dewson et al.   JOURNAL OF CELL SCIENCE

Caspase-independent Mitochondrial Cell Death Results from Loss of Respiration, Not Cytotoxic Protein Release

(2009) Lydia Lartigue et al.   MOLECULAR BIOLOGY OF THE CELL

Mitochondrial Outer Membrane Proteins Assist Bid in Bax-mediated Lipidic Pore Formation

(2009) Blanca Schafer et al.   MOLECULAR BIOLOGY OF THE CELL

Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

(2008) S Lucken-Ardjomande et al.   CELL DEATH AND DIFFERENTIATION

Endophilin B1/Bif-1 Stimulates BAX Activation Independently from Its Capacity to Produce Large Scale Membrane Morphological Rearrangements

(2008) Aitor Etxebarria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Chemical Inhibitor of DRP1 Uncouples Mitochondrial Fission and Apoptosis

(2008) Atsushi Tanaka et al.   MOLECULAR CELL

To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions

(2008) Grant Dewson et al.   MOLECULAR CELL

BAX activation is initiated at a novel interaction site

(2008) Evripidis Gavathiotis et al.   NATURE

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

(2008) Lieven P Billen et al.   PLOS BIOLOGY