Genomic and Network Patterns of Schizophrenia Genetic Variation in Human Evolutionary Accelerated Regions

Exploring the genesis and functions of Human Accelerated Regions sheds light on their role in human evolution

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Evolutionary conservation in genes underlying human psychiatric disorders

(2014) Lisa M. Ogawa et al.   Frontiers in Human Neuroscience

Transcriptional landscape of the prenatal human brain

(2014) Jeremy A. Miller et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A Role for Noncoding Variation in Schizophrenia

(2014) Panos Roussos et al.   Cell Reports

The evolutionary paradox and the missing heritability of schizophrenia

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Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

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The evolution of lineage-specific clusters of single nucleotide substitutions in the human genome

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Many human accelerated regions are developmental enhancers

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A System-Level Transcriptomic Analysis of Schizophrenia Using Postmortem Brain Tissue Samples

(2012) Panos Roussos et al.   ARCHIVES OF GENERAL PSYCHIATRY

INRICH: interval-based enrichment analysis for genome-wide association studies

(2012) Phil H. Lee et al.   BIOINFORMATICS

Evolutionary Meta-Analysis of Association Studies Reveals Ancient Constraints Affecting Disease Marker Discovery

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An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Human brain evolution: From gene discovery to phenotype discovery

(2012) T. M. Preuss   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation

(2012) Jun Zhu et al.   PLOS BIOLOGY

The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

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A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

The evolution of gene expression levels in mammalian organs

(2011) David Brawand et al.   NATURE

Path lengths in protein-protein interaction networks and biological complexity

(2011) Ke Xu et al.   PROTEOMICS

Primate-Accelerated Evolutionary Genes: Novel Routes to Drug Discovery in Psychiatric Disorders

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Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

A genome-wide screen for noncoding elements important in primate evolution

(2008) Eliot C Bush et al.   BMC EVOLUTIONARY BIOLOGY

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

(2008) A. J. Vilella et al.   GENOME RESEARCH

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

(2008) Jun Zhu et al.   NATURE GENETICS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

The ʻbig bangʼ theory of the origin of psychosis and the faculty of language

(2008) T CROW   SCHIZOPHRENIA RESEARCH

Rapid evolving RNA gene HAR1A and schizophrenia

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