Structure and function of histone chaperone FACT

Histone H2A/H2B chaperones: from molecules to chromatin-based functions in plant growth and development

(2015) Wangbin Zhou et al.   PLANT JOURNAL

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells

(2015) Henry Garcia et al.   Oncotarget

FACT plays a major role in histone dynamics affectingVSGexpression site control inTrypanosoma brucei

(2014) Viola Denninger et al.   MOLECULAR MICROBIOLOGY

A Role for FACT in Repopulation of Nucleosomes at Inducible Genes

(2014) Warren P. Voth et al.   PLoS One

Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells

(2013) Alfiya Safina et al.   CELL CYCLE

Structure of the Spt16 Middle Domain Reveals Functional Features of the Histone Chaperone FACT

(2013) David J. Kemble et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myogenin Recruits the Histone Chaperone Facilitates Chromatin Transcription (FACT) to Promote Nucleosome Disassembly at Muscle-specific Genes

(2013) Alexandra A. Lolis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20

(2013) Douglas V. Oliveira et al.   JOURNAL OF CELL SCIENCE

A Highly Conserved Region within H2B Is Important for FACT To Act on Nucleosomes

(2013) S. Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restart after UV-Induced DNA Damage

(2013) Christoffel Dinant et al.   MOLECULAR CELL

Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

(2013) Peter Tessarz et al.   NATURE

Structural basis of histone H2A–H2B recognition by the essential chaperone FACT

(2013) Maria Hondele et al.   NATURE

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription

(2013) Sílvia Carvalho et al.   NUCLEIC ACIDS RESEARCH

Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation

(2013) M. Aida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone chaperone FACT action during transcription through chromatin by RNA polymerase II

(2013) F.-K. Hsieh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Facilitates Chromatin Transcription Complex Is an “Accelerator” of Tumor Transformation and Potential Marker and Target of Aggressive Cancers

(2013) Henry Garcia et al.   Cell Reports

Mechanism of transcription through a nucleosome by RNA polymerase II

(2012) Olga I. Kulaeva et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Targeting FACT Complex Suppresses Mammary Tumorigenesis in Her2/neu Transgenic Mice

(2012) I. E. Koman et al.   Cancer Prevention Research

Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106

(2012) Dan Su et al.   NATURE

New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

(2012) Karolin Luger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of FACT in making and breaking nucleosomes

(2011) Tim Formosa   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication

(2011) Lena R. Kundu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair

(2011) Vijayalakshmi Kari et al.   CELL CYCLE

HP1c casts light on dark matter

(2011) So Hee Kwon et al.   CELL CYCLE

Insight Into the Mechanism of Nucleosome Reorganization From Histone Mutants That Suppress Defects in the FACT Histone Chaperone

(2011) Laura McCullough et al.   GENETICS

The Histone Chaperone FACT: Structural Insights and Mechanisms for Nucleosome Reorganization

(2011) Duane D. Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Chaperone FACT Coordinates Nucleosome Interaction through Multiple Synergistic Binding Events

(2011) Duane D. Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Chaperones: Modulators of Chromatin Marks

(2011) Nikita Avvakumov et al.   MOLECULAR CELL

Selective removal of promoter nucleosomes by the RSC chromatin-remodeling complex

(2011) Yahli Lorch et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes

(2011) Lacramioara Bintu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Yeast H2A.Z, FACT complex and RSC regulate transcription of tRNA gene through differential dynamics of flanking nucleosomes

(2011) Sahasransu Mahapatra et al.   NUCLEIC ACIDS RESEARCH

Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing

(2011) R. M. Zunder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nhp6: A small but powerful effector of chromatin structure in Saccharomyces cerevisiae

(2010) David J. Stillman   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

HMGB proteins: Interactions with DNA and chromatin

(2010) Michal Štros   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Chaperoning Histones during DNA Replication and Repair

(2010) Monica Ransom et al.   CELL

Heterochromatin protein 1 (HP1) connects the FACT histone chaperone complex to the phosphorylated CTD of RNA polymerase II

(2010) S. H. Kwon et al.   GENES & DEVELOPMENT

Ubiquitylation of FACT by the Cullin-E3 ligase Rtt101 connects FACT to DNA replication

(2010) J. Han et al.   GENES & DEVELOPMENT

Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

(2010) A. Stanlie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA polymerase complexes cooperate to relieve the nucleosomal barrier and evict histones

(2010) O. I. Kulaeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1

(2010) Macarena Morillo-Huesca et al.   PLoS Genetics

spFRET Using Alternating Excitation and FCS Reveals Progressive DNA Unwrapping in Nucleosomes

(2009) W.J.A. Koopmans et al.   BIOPHYSICAL JOURNAL

H2A.Z-Containing Nucleosomes Mediate the Thermosensory Response in Arabidopsis

(2009) S. Vinod Kumar et al.   CELL

The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters

(2009) Shinya Takahata et al.   EMBO JOURNAL

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome

(2009) Agnieszka Gambus et al.   EMBO JOURNAL

Phosphorylated Intrinsically Disordered Region of FACT Masks Its Nucleosomal DNA Binding Elements

(2009) Yasuo Tsunaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FACT and the Proteasome Promote Promoter Chromatin Disassembly and Transcriptional Initiation

(2009) Monica Ransom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for SSRP1 in recombination-mediated DNA damage response

(2009) Anuradha Kumari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

FACT and Asf1 Regulate Nucleosome Dynamics and Coactivator Binding at the HO Promoter

(2009) Shinya Takahata et al.   MOLECULAR CELL

Histone Chaperone Spt16 Promotes Redeposition of the Original H3-H4 Histones Evicted by Elongating RNA Polymerase

(2009) Adil Jamai et al.   MOLECULAR CELL

yFACT Induces Global Accessibility of Nucleosomal DNA without H2A-H2B Displacement

(2009) Hua Xin et al.   MOLECULAR CELL

Mechanism of chromatin remodeling and recovery during passage of RNA polymerase II

(2009) Olga I Kulaeva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication

(2009) Tomás Aparicio et al.   NUCLEIC ACIDS RESEARCH

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

Rapid, Transcription-Independent Loss of Nucleosomes over a Large Chromatin Domain at Hsp70 Loci

(2008) Steven J. Petesch et al.   CELL

Histone N-terminal Tails Interfere with Nucleosome Traversal by RNA Polymerase II

(2008) Andrea Újvári et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FACT and the reorganized nucleosome

(2008) Tim Formosa   Molecular BioSystems

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation

(2008) Wenlai Zhou et al.   MOLECULAR CELL

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

The FACT Spt16 “peptidase” domain is a histone H3–H4 binding module

(2008) Tobias Stuwe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information

(2008) Armelle Corpet et al.   TRENDS IN CELL BIOLOGY

Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome

(2008) Vanessa Cheung et al.   PLOS BIOLOGY