Article
Engineering, Chemical
Joshua D. Moon, Hailun Borjigin, Ran Liu, Ronald M. Joseph, Judy S. Riffle, Benny D. Freeman, Donald R. Paul
Summary: Polybenzimidazoles (PBIs) have promising potential for high temperature H-2/CO2 separation applications, but their gas separation properties are affected by humidity. Water uptake reduces PBI gas permeabilities at low humidities through competitive sorption and antiplasticization, while at high humidities, plasticization increases permeabilities of larger gases in more hydrophilic PBIs. Water plasticizes PBIs by enhancing molecular dynamics to increase accessible free volume rather than creating new free volume cavities.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Chemistry, Applied
Pierre Bonin, Aurelien Roggero, Nicolas Causse, Nadine Pebere, Dominique Thierry, Nathalie Le Bozec
Summary: This study characterized an industrial polyester coil-coated steel sample using electrochemical impedance spectroscopy, with a focus on understanding how water uptake affects the physical properties of the coil coating and extracting relevant parameters of the ageing processes. The water uptake was found to be a slow process, with different sorption kinetics observed for samples with different initial states.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Pharmacology & Pharmacy
Nirali G. Patel, Sabrina Banella, Abu T. M. Serajuddin
Summary: Moisture sorption by different polymers used in amorphous solid dispersion (ASD) was investigated, and the effects of moisture on glass transition temperatures (Tg) of the polymers were determined. Among the polymers studied, Eudragit (R) EPO exhibited the least hygroscopicity, while the other three polymers absorbed more moisture. The apparent Tg of the polymers decreased with increasing moisture content, but remained higher than the usual storage temperature of ASD, indicating minimal impact on the physical stability of ASD.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Review
Green & Sustainable Science & Technology
Charles G. Bradley, Lucia Corsini
Summary: Over 161 million tonnes of plastic packaging is produced annually, yet only a small fraction of plastic packaging is recycled. To help eliminate unnecessary plastic packaging and its associated pollution, interest is growing in re-usable packaging systems, such as returnable and refillable packaging. However, it cannot be assumed that reus-able packaging systems will be more sustainable than single-use alternatives.
SUSTAINABLE PRODUCTION AND CONSUMPTION
(2023)
Article
Engineering, Chemical
Ehsan Soroodan Miandoab, Sandra E. Kentish, Colin A. Scholes
Summary: A mathematical model of membrane performance incorporating various factors such as fugacity-dependent permeabilities, competitive sorption, penetrant blocking, and plasticization effects was developed. The model considers real gas behavior, concentration polarization, and the influence of water vapor and carbon dioxide on plasticization. Simulation results showed significant differences in methane recovery and CO2 removal between the new model and simplified models, with the new model showing higher accuracy in predicting these values.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Polymer Science
Petr Cihal, Marcela Dendisova, Marie Svecova, Zdenek Hrdlicka, Tereza-Marketa Durdakova, Peter M. Budd, Wayne Harrison, Karel Friess, Ondrej Vopicka
Summary: The study of PIM-1 membranes in vapour mixtures of methanol and DMC revealed promising potential for the efficient recovery of organic components. The membranes exhibited high rigidity and selectivity to DMC in various saturation and composition ranges, making them a candidate for effective inversely selective vapour separation membranes.
Article
Chemistry, Physical
An'an Zhou, Qianqian Yang, Ke Xu, Qiang Zhou, Jianyang Wu, Hua Bai
Summary: This study provides new insights into the elasticity of chemically modified graphene aerogels and demonstrates the influence of water molecules on the surface plasticization of the aerogels. By reducing the surface hydrophilicity with thermal treatment, the elasticity of the aerogels can be enhanced.
Article
Chemistry, Applied
Wen Li, Liyuan Yun, Yunjiao Zhao, Zijian Zhi, Esther Mwizerwa Muhindo, Xiaoyuan Geng, Rui Liu, Tao Wu, Wenjie Sui, Min Zhang
Summary: This study investigates the impact of different disaccharides on the water sorption performance of dextran mixtures. The results show that dextran combined with sucrose exhibits better water sorption properties compared to other mixtures, and the Guggenheim constant increases with higher dextran ratios. Trehalose and lactose are found to be more effective in preserving the morphological stability of the hydrous matrices in the mixtures.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Physical
Mincheng Yang, Ziqiu Wang, Peng Li, Yingjun Liu, Jiahao Lin, Bo Wang, Xin Ming, Weiwei Gao, Zhen Xu, Chao Gao
Summary: The stress relaxation behavior of graphene fiber (GF) was studied, revealing a severe stress drop for nascent GF. The drop in stress during relaxation decreased with the promotion of the orientation degree and crystallinity. Plasticization stretching strategy and graphitization process were presented to relieve the relaxation of GF, accompanying with excellent mechanical strength.
Article
Chemistry, Applied
R. G. M. van der Sman, A. Jurgens, A. Smith, S. Renzetti
Summary: In this paper, a sugar replacements strategy based on physical theory is presented, which aims to improve the texture of food by mimicking the physical properties of sugar. Experimental determination and sensory evaluation demonstrate the effectiveness of the strategy, and also suggest the possibility of further optimization.
FOOD HYDROCOLLOIDS
(2022)
Article
Materials Science, Ceramics
Montserrat Espanol, Emilia Davis, Eliott Meslet, Gemma Mestres, Edgar B. Montufar, Maria-Pau Ginebra
Summary: The high-temperature polymorph of tricalcium phosphate, α-TCP, can hydrolyze to calcium-deficient hydroxyapatite under humidity conditions, which is essential for the development of synthetic bone grafts. The study found that high relative humidity had no immediate impact on α-TCP powder reactivity, but prolonged incubation led to hydrolysis. This reactivity was related to defects and an amorphous phase induced during powder milling. Dynamic moisture studies showed irreversible water sorption and confirmed that water molecules reacted with the powder after a short incubation time.
CERAMICS INTERNATIONAL
(2023)
Article
Pharmacology & Pharmacy
Clara E. Correa-Soto, Yi Gao, Anura S. Indulkar, Geoff G. Z. Zhang, Lynne S. Taylor
Summary: Amorphous solid dispersion formulations (ASD) are used to improve the bioavailability of poorly soluble drugs. This study investigated the addition of surfactants to atazanavir-copovidone ASDs to increase the limit of congruency (LoC). The results showed that addition of certain surfactants increased the LoC and enhanced drug release from the ASDs.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Chemistry, Applied
Nicolas Causse, Pierre Bonin, Dominique Thierry, Nathalie Le Bozec, Aurelien Roggero, Nadine Pebere
Summary: In this study, the characteristics of an industrial polyester coil-coated steel immersed in a 0.5 M NaCl solution at different temperatures (30, 40, 50, and 60 degrees C) were analyzed using electrochemical impedance spectroscopy (EIS). The aim was to propose a methodology to track the aging of the coil-coated system and understand the processes of polymer and metal/polymer interface aging. The water uptake and its effect on the physical structure of the coating were determined, and corrosion was detected at higher temperatures through impedance spectra analysis.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Materials Science, Composites
Nadia Hartini Suhaimi, Yin Fong Yeong, Norwahyu Jusoh, Thiam Leng Chew, Mohamad Azmi Bustam, Muhammad Mubashir
Summary: The study systematically investigated the transport properties and plasticization behavior of CO2 and CH4 in 6FDA-based mixed matrix membranes filled with nonfunctionalized and amine-functionalized MIL-125 (Ti) particles. The addition of fillers resulted in significantly increased permeability of CO2 and ideal selectivity of CO2/CH4 due to altered sorption and diffusion properties of the membrane. Additionally, the CO2 plasticization resistance was greatly improved in the mixed matrix membranes compared to the neat membrane.
POLYMER COMPOSITES
(2022)
Article
Engineering, Chemical
Karol Kubat, Dominik Strojewski, Dorota Majda, Daniel Jakubiec, Aleksandra Andrzejowska, Agata Bogda, Anna Krupa, Hubert Haranczyk
Summary: Amorphous bosentan lacks dissolution flux, but coamorphization with copovidone improves wettability and dissolution rate. However, fine amorphous particles are prone to moisture uptake, which can alter physical properties and state. The properties of copovidone greatly impact water sorption, resulting in phase changes. State diagrams are developed for optimization of manufacturing conditions and long-term stability.
Article
Pharmacology & Pharmacy
Greta Camilla Magnano, Marika Quadri, Elisabetta Palazzo, Roberta Lotti, Francesca Loschi, Stefano Dall'Acqua, Michela Abrami, Francesca Larese Filon, Alessandra Marconi, Dritan Hasa
Summary: This study aimed to investigate the loading of sildenafil citrate in three commercial transdermal vehicles using 3D full-thickness skin equivalent and compare the results with permeability experiments using porcine skin. The results showed that the results obtained using the 3D skin equivalent were comparable to those obtained using porcine skin, suggesting that the 3D skin model can be a valid alternative for ex-vivo skin absorption experiments.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2024)
Article
Pharmacology & Pharmacy
James W. Mckeage, Andrew Z. H. Tan, Andrew J. Taberner
Summary: Needle-free jet injection is a promising alternative drug delivery technique that offers rapid, non-invasive, and large-volume injections. The study presents a prototype multi-orifice nozzle and a computational fluid dynamic model to demonstrate the feasibility and effectiveness of this technology.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2024)
