Article
Multidisciplinary Sciences
Yue Fan, Dongdong Li, Pu Wang, Lili Ren, Xiaowei Chen
Summary: This study found a relationship between acute otitis media (AOM) in children with viral upper respiratory infection (URI) and infection by common respiratory viruses. Among the 255 children examined, 164 (64.1%) tested positive for at least one respiratory virus, with respiratory syncytial virus (RSV) being the most common. The presence of RSV was significantly higher in children with URI + AOM compared to those with URI alone.
Article
Nutrition & Dietetics
Yvan Vandenplas, Marta Zolnowska, Roberto Berni Canani, Sian Ludman, Zsuzsanna Tengelyi, Ana Moreno-alvarez, Anne E. N. Goh, Maria Laura Gosoniu, Bridget-Anne Kirwan, Monika Tadi, Ralf G. Heine
Summary: This clinical trial demonstrates that an extensively hydrolyzed formula supplemented with HMO supports normal growth in infants with CMPA and provides a protective effect against respiratory and ear infections.
Article
Immunology
Michael E. Pichichero, Timothy J. Chapman, Peter Bajorski
Summary: The study revealed that otitis-prone children are more susceptible to respiratory infections, showing higher rates of pneumonia, acute sinusitis, and influenza compared to non-otitis-prone children. This increased susceptibility was present from 6 months to 5 years of age, indicating the importance of monitoring and managing respiratory infections in otitis-prone children.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Review
Immunology
Luanne Hall-Stoodley, Karen S. McCoy
Summary: This review discusses the formation of biofilms in the airway, their role in defending against infection, and the pathophysiology and dysfunctional mechanisms associated with biofilm infections. It also briefly discusses evaluating and treating airway-associated biofilm infections.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Infectious Diseases
Bhavna Samtani, Natasha Gray, Jessica Omand, Charles Keown-Stoneman, Mary Aglipay, Catherine Birken, Jonathon Maguire
Summary: This study found that children who received an antibiotic prescription for upper respiratory tract infection (URTI) before the age of 2 had 1.4 times higher odds of receiving an antibiotic prescription for URTI in later childhood, and this relationship did not appear to differ between acute otitis media (AOM) and non-AOM URTI.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
(2022)
Article
Multidisciplinary Sciences
Lei Xu, Joshua Earl, Michael E. Pichichero
Summary: Analysis of microbiota composition in the nasopharynx of children revealed correlations between certain genera and Streptococcus pneumoniae colonization, with Corynebacterium showing a consistent inverse relationship. Corynebacterium propinquum and C. pseudodiphtheriticum were found to inhibit the growth of Spn serotype 22F strain in vitro.
Article
Immunology
Kalyan K. Dewan, Colleen Sedney, Amanda D. Caulfield, Yang Su, Longhuan Ma, Uriel Blas-Machado, Eric T. Harvill
Summary: Acute otitis media is a common disease caused by bacterial pathogens in the nasopharynx. By using a mouse model, researchers found that Bordetella bronchiseptica can also cause middle ear infections in mice, providing a flexible model for studying naturally occurring acute otitis media. Mice lacking T and/or B cells were unable to clear the infection, highlighting the cooperative role of both in clearing middle ear infection. Furthermore, adoptively transferred antibodies provided protection to the lungs but only partial protection to the middle ears, revealing the differences between respiratory and otoimmunology.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Virology
Mariana C. Leal, Danielle Seabra Ramos, Thiago Pinto Bezerra, Ana Elizabeth S. C. Vilela, Rebeka Jacques de F. Maciel, Mirella Rodrigues, Mariana Lira, Karen Pena de Souza Cavalcanti, Vanessa van der Linden, Marli T. Cordeiro, Democrito Miranda-Filho, Ricardo Ximenes, Elizabeth B. Brickley, Silvio S. Caldas
Summary: A study on children with ZRM showed a high prevalence of adenoid hypertrophy (AH) leading to upper airway obstruction, which may cause issues such as upper airway obstructive disorder, secretory otitis media, and dysphagia. Surgery may help resolve symptoms in some cases.
Review
Nutrition & Dietetics
Alessandro Fiocchi, Jan Knol, Sibylle Koletzko, Liam O'Mahony, Nikolaos G. Papadopoulos, Seppo Salminen, Hania Szajewska, Anna Nowak-Wegrzyn
Summary: Acute respiratory infections are a common cause of morbidity in infants and young children, impacting healthcare resources and antibiotic use, and potentially leading to antibiotic resistance and changes in intestinal microbiota composition. Through international collaboration, researchers are exploring the links between infant feeding, cow's milk allergy, and infection risk, with a focus on strategies to improve infection outcomes and reduce antibiotic usage in vulnerable populations like infants with CMA.
Article
Neurosciences
Wei Meng, Dong-Dong Huang, Guang-Fei Li, Zi-Hui Sun, Shuang-Ba He
Summary: This study aimed to treat and follow up children with acute nonsuppurative otitis media induced by acute upper respiratory tract infection. The results showed varying therapeutic effects based on different severity grades, with some cases requiring surgical intervention for improvement.
Article
Pediatrics
Oren Ziv, Dana Adelson, Reem Sadeh, Sofia Kordeluk, Sabri El-Saied, Eugene Leibovitz, Mordechai Kraus, Daniel Kaplan
Summary: This retrospective cohort study showed that immunization with pneumococcal conjugate vaccines (PCV) significantly reduced the occurrence of recurrent acute otitis media (rAOM) in infants following an early episode of acute otitis media (AOM).
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Review
Immunology
Tal Marom, Jacob Pitaro, Udayan K. Shah, Sara Torretta, Paola Marchisio, Ayan T. Kumar, Patrick C. Barth, Sharon Ovnat Tamir
Summary: The global COVID-19 pandemic has had an impact on the management of pediatric infectious diseases, including AOM. The new coronavirus, SARS-CoV-2, is responsible for COVID-19, and previous coronavirus serotypes were rarely detected in AOM cases. Preventive measures and changes in healthcare practices have affected the diagnosis and treatment of AOM during the pandemic.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Pediatrics
Sara Torretta, Pasquale Capaccio, Ilaria Coro, Samantha Bosis, Maria Elisabetta Pace, Pietro Tosi, Lorenzo Pignataro, Paola Marchisio
Summary: During the COVID-19 pandemic lockdown in Italy, otitis-prone children in Milan showed significant clinical improvement, with a decrease in acute otitis media episodes, otorrhea episodes, and antibiotic treatments when compared to the same period in 2019. Telemedicine assessment played a crucial role in maintaining patient care during the lockdown and led to unexpected positive outcomes.
EUROPEAN JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, Research & Experimental
Jong-Yeup Kim, Inseok Ko, Dong-Kyu Kim, Myeong Sang Yu
Summary: This study found that adenotonsillectomy does not alter the frequency of upper airway infections in children. There were no significant differences in the incidence of acute pharyngitis, rhinosinusitis, or otitis media between the adenotonsillectomy group and control group from postoperative year 1 to year 9. The hospital visits for these diseases gradually decreased over time in both groups.
Article
Infectious Diseases
Briallen Lobb, Matthew C. Lee, Christi L. McElheny, Yohei Doi, Kristin Yahner, Alejandro Hoberman, Judith M. Martin, Jeremy A. Hirota, Andrew C. Doxey, Nader Shaikh
Summary: This study used genomics-based analysis to sequence and analyze 148 bacterial isolates from children, identifying sequence types and antibiotic resistance of Streptococcus pneumoniae and Haemophilus influenzae. The research lays the groundwork for the clinical application of genomics-based workflows in detecting and analyzing these pathogens.
BMC INFECTIOUS DISEASES
(2023)
Article
Otorhinolaryngology
Mosaad Abdel-Aziz, Ahmed Talaat, Abdel-Rahman El-Tahan, Ahmed Kamel, Hassan Ghandour, Asmaa Abdel-Hameed
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2020)
Article
Surgery
Mosaad Abdel-Aziz
JOURNAL OF CRANIOFACIAL SURGERY
(2020)
Article
Surgery
Mosaad Abdel-Aziz, Nada M. Abdel-Aziz, Dina M. Abdel-Aziz, Noha Azab
Summary: Recent history of smell disorder may be a potential predictor for COVID-19. Subjective assessment of smell is a rapid procedure that can be used as an office-based method for patients' screening in COVID-19 era. Smell disorder could serve as an alarming sign for COVID-19 even in the absence of characteristic symptoms.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Review
Otorhinolaryngology
Sameh M. Zamzam, Mosaad Abdel-Aziz, Ahmed Atef, Usama Abdel-Naseer, Mostafa Hamoda, Mohamed Salah, Hazem Dewidar, Louay Elsharkawy, Mena E. Abdelmalek
Summary: Randomized controlled trials are crucial for generating evidence in clinical research and providing strong evidence for evidence-based patient care, but efficiently conducting them can be challenging in various aspects.
EGYPTIAN JOURNAL OF OTOLARYNGOLOGY
(2021)
Article
Surgery
Mosaad Abdel-Aziz, Usama Abdel-Naseer, Eslam Elshahawy, Motaz Elsherbeeny, Ahmed Nassar
Summary: The study aimed to evaluate the efficacy of drug-induced sleep endoscopy (DISE)-directed treatment in managing persistent obstructive sleep apnea (OSA) in children with Down syndrome (DS) who underwent adenotonsillectomy. The results showed that DISE-directed treatment significantly improved the apnea-hypopnea index in these patients.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Surgery
Mosaad Abdel-Aziz, Noha Azab
Summary: Acute invasive fungal rhinosinusitis, a rare and highly fatal disease mainly affecting immunocompromised patients, has been increasingly linked to rhino-orbital-cerebral mucormycosis in COVID-19 patients. Predisposing factors may include diabetes, steroid therapy, broad-spectrum antibiotics, hospital-acquired infections, elevated serum ferritin levels, endothelial damage, and pancreatic islets affection among COVID-19 patients. Early diagnosis and prompt treatment are crucial for improving outcomes in COVID-19 patients with craniofacial mucormycosis.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Editorial Material
Otorhinolaryngology
Mosaad Abdel-Aziz, Noha Azab, Nada M. Abdel-Aziz, Dina M. Abdel-Aziz
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Mosaad Abdel-Aziz, Ahmed Nassar, Omar Sabry
Summary: This study found that adenoid hypertrophy is a common pathological finding in children with antrochoanal polyp (ACP), with 90.7% of patients having associated nasal pathology and adenoid hypertrophy being the most common. Endoscopic removal of ACP with concomitant adenoidectomy was shown to be effective, with no adenoid regrowth postoperatively, but a recurrence rate of 11.6% for ACP.
EGYPTIAN JOURNAL OF OTOLARYNGOLOGY
(2021)
Article
Surgery
Mosaad Abdel-Aziz, Gamal Abdel-Fattah, Nada M. Abdel-Aziz, Omar Sabry, Motaz Elsherbeeny
Summary: This study aimed to evaluate the feasibility of performing tonsillectomy and Furlow palatoplasty simultaneously as a 1-stage operation in patients with submucous cleft palate (SMCP) and tonsillar hypertrophy. The results showed improved speech and velopharyngeal function postoperatively, as well as decreased daytime sleepiness. Therefore, simultaneous performance of these two procedures in 1 sitting is logical to avoid postoperative sleep-related breathing disorder and the need for a second stage operation.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Review
Otorhinolaryngology
Sameh M. Zamzam, Mosaad Abdel-Aziz, Ahmed Atef, Usama Abdel-Naseer, Mostafa Hamoda, Mohamed Salah, Hazem Dewidar, Louay Elsharkawy, Mahmoud Fawzy, Mohamed Shabana, Mostafa Elkhosht, Hussan Eldesouky, Hussien Sherif Hamdy
Summary: This article provides a comprehensive review on study designs in otolaryngology and the corresponding reporting guidelines, helping authors understand and accurately report their research findings.
EGYPTIAN JOURNAL OF OTOLARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Mosaad Abdel-Aziz, Aisha Fawzy Abdel Hady, Ayatallah Raouf Sheikhany, Ahmed Ibrahim Yousef, Omar Aly Sabry, Heba Mahomoud Farag
Summary: This study investigated the effect of adenoid size on post-adenoidectomy hypernasality in children. The results showed that preoperative hyponasality was significantly related to the adenoid size, while postoperative hypernasality was related to the preoperative adenoid size. However, transient hypernasality generally resolved within 3 months.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Review
Otorhinolaryngology
Mosaad Abdel-Aziz, Ahmed Atef, Omar Aly Sabry, Ahmed Ibrahim Yousef, Ahmed Salah Ahmed, Ahmed Abo Hussien, Mohamed Abdel-Haleem, Amr Samir
Summary: The debate about the superiority of surgical techniques for tonsillectomy continues. Cold and hot techniques are the classification of tonsillectomy procedures. Cold techniques include dissection, guillotine, microdebrider, harmonic scalpel, and cryosurgery, while hot techniques include electrocautery, coblation, radio frequency, and laser. In Egypt, the commonly used methods are cold dissection, electrocautery, cold dissection with electrocautery hemostasis, coblation, and laser less commonly. This study describes the advantages and disadvantages of each technique.
EGYPTIAN JOURNAL OF OTOLARYNGOLOGY
(2023)
Article
Medicine, General & Internal
Mosaad Abdel-Aziz, Gamal Abdel-Fattah, Nada M. Abdel-Aziz
Summary: Encountering a nasopharyngeal polyp in a patient with submucous cleft palate (SMCP) can be challenging, as removal of the polyp may lead to worsened speech nasality. However, performing trans-nasal endoscopic removal of the polyp and using a superiorly-based pharyngeal flap in one sitting is an effective approach without adverse effects on the patient's speech.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Otorhinolaryngology
Mosaad Abdel-Aziz, Ahmed Nassar, Refaat Nashed, Moatz Elsherbeeny, Omar Sabry
EGYPTIAN JOURNAL OF OTOLARYNGOLOGY
(2020)
Article
Otorhinolaryngology
Mosaad Abdel-Aziz, Abdel-Rahman El-Tahan, Assem Abdel-Wahid, Ahmed Kamel
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2020)
Article
Otorhinolaryngology
Adrian Williamson, Erica H. Mcardle, Hussein Jaffal
Summary: This study aims to describe the findings on drug-induced sleep endoscopy (DISE) in infants with laryngomalacia (LM). The results showed that DISE can identify obstruction at the level of the tongue base and complement the assessment of LM severity.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Tanya Chen, Melissa Lee, Evelyn Constantin, Joshua Gurberg, Lily HP. Nguyen
Summary: In the last two decades, there has been a high prevalence of funding and potential conflicts of interest in HSAT publications. Higher quality studies have increased in the last five years, but there still exists a lack of disclosure regarding funding or COI. There is a positive correlation between level of evidence and industry funding.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Stephen I. Pelton, Saskia Hullegie, Amanda J. Leach, Paola Marchisio, Tal Marom, Vishakha Sabharwal, Nader Shaikh, Paula A. Tahtinen, Roderick P. Venekamp
Summary: This study aims to identify and synthesize key research advances in the preventative measures and medical and surgical treatment of uncomplicated otitis media (OM), as well as the impact of the COVID-19 pandemic on OM management. The study found that there have been important advances in OM management in recent years, such as the effectiveness of video discharge instructions in reducing symptoms for parents of children with acute otitis media (AOM) and the efficacy of levofloxacin solution for treating chronic suppurative otitis media.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Thomas L. Haupt, Earl H. Harley
Summary: This study analyzed head and neck injuries caused by BB guns among children under 18 treated in US emergency departments between 1993 and 2019. It found that younger children are at increased risk of hospital admission, and injuries to the eye and neck are strong predictors of hospitalization.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Guy Faibish, Daniel Kaplan, Ariela Knaanie, Sabri Elsaeid, Oren Ziv
Summary: This study compared postoperative complication rates in pediatric cochlear implant candidates with and without otitis media with effusion (OME), and found that ventilation tube insertion for OME increased the rates of acute mastoiditis and chronic suppurative otitis media without cholesteatoma (CSOMWC).
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Andrew T. Gabrielson, Julie Wei
Summary: A survey conducted among members of the American Society of Pediatric Otolaryngology (ASPO) found that pediatric otolaryngologists commonly experience work-related musculoskeletal pain and lack knowledge about surgical ergonomics.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Review
Otorhinolaryngology
Alisha R. Pershad, Emily C. Knox, Rahul K. Shah, Habib G. Zalzal
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Keerthana Rajanbabu, Sakthilakshmi Gunasekaran, Heramba Ganapathy Selvarajan
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)
Article
Otorhinolaryngology
Austin D. Schafer, Megan Mcnutt, Amy Fulmer, Tran Bourgeois, Charles A. Elmaraghy
Summary: This study compared the risk of recurrent epistaxis in children treated with silver nitrate or electrocautery. The findings showed that patients treated with silver nitrate had significantly higher risk of recurrence compared to those treated with electrocautery.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2024)