Article
Biotechnology & Applied Microbiology
Philipp Ruf, Vincenzo Orassi, Heilwig Fischer, Claudius Steffen, Georg N. N. Duda, Max Heiland, Kilian Kreutzer, Sara Checa, Carsten Rendenbach
Summary: This study evaluated the primary fixation stability of CAD/CAM fixators and compared the performance of different types of fixators under biomechanical conditions. The results showed that CAD/CAM miniplates had higher mechanical strains, while CAD/CAM reconstruction plates resulted in higher strains. However, the stresses in the fixation systems were below the material yield stress, indicating that material failure would not be expected.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Computer Science, Information Systems
Lun Yan, Xingce Wang, Zhongke Wu
Summary: This study focuses on the rapid reconstruction of 3D personalized mandibles, especially in cases of severe damage or total loss. An example-oriented method based on PCA is used to reconstruct the 3D shapes of mandibles, and experiments show higher accuracy compared to state-of-the-art methods.
MULTIMEDIA TOOLS AND APPLICATIONS
(2022)
Article
Chemistry, Analytical
Rene Marcel Rothweiler, Sergej Zankovic, Leonard Simon Brandenburg, Marc-Anton Fuessinger, Christian Gross, Pit Jacob Voss, Marc-Christian Metzger
Summary: Nonunion is a dreaded complication after operative treatment of mandible fractures or reconstruction, and continuous monitoring devices are urgently needed. Strain measurement of plates is a promising approach, although the current device is not suitable for monitoring in the mandibular body.
Review
Physiology
Ana Prates Soares, Heilwig Fischer, Sabrin Aydin, Claudius Steffen, Katharina Schmidt-Bleek, Carsten Rendenbach
Summary: The mandible is responsible for shaping the lower face, masticatory movements, and articulation of phonemes. Pathologies that damage the mandible severely impact patients. Mandibular reconstruction techniques using flaps, notably free vascularized fibula flaps, need to consider the unique clinical traits and differences of the mandible to achieve successful outcomes.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Medicine, Research & Experimental
Edward Wang, Khanh Linh Tran, Emmanuel D'heygere, Eitan Prisman
Summary: Using a statistical shape model to predict the shape of a distorted mandible is more accurate for smaller defects, and it outperforms current preprocessing techniques.
Article
Pediatrics
Shupei Jiang, Tao Han, Weimin Shen
Summary: This study aimed to measure the related indicators of the neonatal mandible in East China. Data of normal neonates were collected and reconstructed into 3D models for measurement. No statistical differences were found between male and female neonates for the measured indicators, and the normal reference values were obtained.
FRONTIERS IN PEDIATRICS
(2023)
Article
Otorhinolaryngology
Christian Brauer, Katrin Ullmann, Gunter Lauer, Adrian Franke, Niall M. H. Mcleod, Henry Leonhardt
Summary: A modification of the treatment method for mandible reconstruction using laser-sintered CAD-CAM plates instead of manually bent miniplates was found to prevent plate fractures and achieve successful wound healing in 86% of cases. This modification offers a treatment option for elderly, multimorbid patients in palliative situations and avoids donor site morbidity.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Multidisciplinary Sciences
Manuel Pinheiro, Robin Willaert, Afaq Khan, Anouar Krairi, Wim Van Paepegem
Summary: This study investigates the biomechanical implications of temporomandibular joint (TMJ) replacement implants on masticatory function, finding differences in mandibular displacement and principal strain patterns compared to intact joints. Re-attaching the lateral pterygoid may increase anterior-posterior displacement, highlighting the need for new TMJ implant designs to stabilize condylar movement and promote natural load transmission.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Julian Lommen, Lara Schorn, Christoph Sproll, Norbert R. Kuebler, Luis Fernando Nicolini, Ricarda Merfort, Ayimire Dilimulati, Frank Hildebrand, Majeed Rana, Johannes Greven
Summary: This study evaluated the mechanical fatigue of different polymer plates for mandible reconstruction. The results showed that fiber-reinforced polyetheretherketone, polyetheretherketone, and polyetherketoneketone were able to withstand expected bite forces and had sufficient mechanical strength for mandible reconstruction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Kamil Nelke, Klaudiusz Luczak, Maciej Janeczek, Edyta Pasicka, Krzysztof Zak, Marceli Lukaszewski, Radoslaw Jadach, Maciej Dobrzynski
Summary: There are various cysts and tumors in the mandibular and maxillary bones, with origins either odontogenic or otherwise. The odontogenic keratocyst (OKC) is a common example of an odontogenic cyst. Although the treatment methods for OKC have not changed significantly, it has a higher recurrence rate compared to other odontogenic cysts. The size, location, and cortical expansion of the OKC can influence the treatment and potential recurrence. Individual cases may require bone grafting or other reconstruction methods. Proper treatment of the bone cavity after cyst removal is crucial for preventing pathological fractures or improper healing. Healing potential can be improved with xenograft bone substitutes or allograft fresh-frozen bones. In rare cases, a titanium plate may be used for mandibular stability. This case report presents an atypical case of a large OKC treated with fresh-frozen bone grafts and supported with collagen barrier material.
APPLIED SCIENCES-BASEL
(2023)
Article
Oncology
Shirly Grynberg, Marilena Vered, Ronnie Shapira-Frommer, Nethanel Asher, Guy Ben-Betzalel, Ronen Stoff, Yael Steinberg, Ninette Amariglio, Gahl Greenberg, Iris Barshack, Amos Toren, Ran Yahalom, Jacob Schachter, Gideon Rechavi, Ariel Hirschhorn, Gadi Abebe Campino
Summary: Neoadjuvant BRAF inhibition may be a safe and effective strategy for preserving the mandible in the treatment of ameloblastoma.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Biology
Jiangchang Xu, Jiannan Liu, Dingzhong Zhang, Zijie Zhou, Chenping Zhang, Xiaojun Chen
Summary: The paper proposed a 3D automatic mandibular segmentation network with multiple convolutional modules and edge supervision, optimizing features and implementing multi-scale feature search to improve segmentation performance. The network can quickly and accurately segment Non-MTI and MTI within 7.41 seconds, with high segmentation accuracy.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Biology
Qimin Shi, Yi Sun, Shoufeng Yang, Jeroen Van Dessel, Heinz-Theo Lubbers, Shengping Zhong, Yifei Gu, Michel Bila, Constantinus Politis
Summary: The combination of long and short titanium plates showed superior biomechanical properties for mandible reconstruction compared to a conventional single long plate. It provided higher safety, lower fixation instability, and good bone segment stability during masticatory activities. This preclinical evidence supports the feasibility of using short plates for complete mandible reconstruction and may have implications for treating other large-sized bone defects with customised implants using additive manufacturing technology.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Review
Medicine, Research & Experimental
Julia Walatek, Andrzej Mysliwiec, Lukasz Krakowczyk, Wojciech Wolanski, Anna Lipowicz, Krzysztof Dowgierd
Summary: Mandible tumors are rare and one treatment method is resecting the tumor and reconstructing the mandible using distant tissue such as fibula or ilium. Physiotherapy after tumor resection and mandible reconstruction is complex as it involves restoring mandible function and improving the donor site area. This bibliographic review aims to provide effective physiotherapeutic procedures by finding reconstruction methods and assessing patient function.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jun Zhang, Yujing Wang, Lulu Yuan, Weiren Wang
Summary: The study found that masticatory performance and subjective chew function were significantly affected in the short term after OFF flap reconstructions, but both recovered to preoperative levels within 9-12 months postoperatively.
