Article
Pharmacology & Pharmacy
Haiyue Zhao, Yating Yu, Ni Ni, Lijie Zhao, Xiao Lin, Youjie Wang, Ruofei Du, Lan Shen
Summary: A new parameter highly relevant to tablet friability is proposed based on a systematical study of tablet quality attributes and texture performances of different excipients. A design space is developed for fast identification of tablets with acceptable friability.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Cell Biology
Shiyong Ling, Chen Yan, Kai Huang, Bo Lv, Hua Wang, Xiaoyan Wang, Jun Chen, Jingchuan Sun
Summary: This study discussed the effects of the PTEN-mediated TGF-beta/Smad2 pathway on osteogenic differentiation in osteoporotic (OP) tibial fracture rats and bone marrow mesenchymal stem cells (BMSC) under tension. The results showed that upregulation of PTEN led to decreased expression of TGF-beta and Smad2 proteins, while downregulation of PTEN and upregulation of TGF-beta/Smad2 signal promoted osteogenic differentiation of BMSC under tension.
CELLULAR MICROBIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Rui Xu, Yulong He, Xin Li, Minghui Lu, Yanfeng Chen
Summary: A novel snap-fit based modular multistable mechanical metamaterial was proposed for energy absorbing, which exhibits excellent impact resistance and energy absorption capacity. It can be considered as a potential candidate in the development of shock absorbers, and also has applications in various other fields and devices.
APPLIED MATERIALS TODAY
(2023)
Article
Materials Science, Composites
Yingxiang Li, Hui Lu, Zhong-Yan Zhang, Hong Liu, Zhao-Yan Sun
Summary: We studied the formation of cross-linked network material through the chains end-group reaction of grafted nanoparticles using molecular dynamics simulation. Our findings suggest that a reaction-limited process is more preferable for fabricating a crosslinked network structure with relatively homogeneous crosslinking points. Additionally, the length of grafted chains plays a crucial role in regulating the distribution of crosslinking points and the mechanical properties of composite materials.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Xingfu Li, Zhenghong Zhang, Yunhua Bai, Yifeng Liu, Yang Liu, Cong Li, Zhengrong Fu, Hongjiang Pan, Jingran Yang, Xinkun Zhu
Summary: This study systematically investigated the mechanical properties of Cu-4.5Al-SMAT specimens processed by surface mechanical attrition treatment (SMAT). The results showed that the hardness exhibited a gradient variation along the thickness after SMAT, which was related to the gradient defects. The mechanical incompatibility between gradient layers of the specimen was associated with the degree of hardness gradient, and the reduction of hardness gradient led to a decrease in strain hardening. The combination of gradient structure and coarse-grained matrix induced dispersed strain bands on the GS surface, resulting in high yield strength and considerable ductility.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Biochemistry & Molecular Biology
Ching-Hao Chen, Chun-Hou Liao, Kuo-Chiang Chen, Kuan-Lin Wang, Xiao-Wen Tseng, Wei-Kung Tsai, Han-Sun Chiang, Yi-No Wu
Summary: Interstitial cystitis (IC) is a chronic inflammatory disease characterized by bladder pain and increased urinary frequency. This study compared bladder function changes in FVB and B6 mouse strains with IC, showing significant anatomical and functional differences, with B6 strain being more suitable for IC models.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Polymer Science
Chunqing Si, Xintong Tian, Yan Wang, Zhigang Wang, Xinfang Wang, Dongjun Lv, Aili Wang, Fang Wang, Longlong Geng, Jing Zhao, Ruofei Hu, Qingzeng Zhu
Summary: This paper documents the preparation of PVA-tannic acid (TA) gels with exceptional properties and analyzes the effect of tannic acid on the mechanical properties of the gels. The results show that the PVA-TA gels have high tensile strength, elongation at break, and toughness. In addition, the transparent PVA-TA gels can effectively prevent ultraviolet-light-induced degradation. This study provides a novel strategy and reference for the design and preparation of high-performance gels.
Article
Materials Science, Multidisciplinary
H. Jin, B. Sanborn, W-Y Lu, B. Song
Summary: Mechanical characterization of a 304L-VAR stainless steel was conducted under low, intermediate, and high strain rates using different apparatuses. Tensile stress-strain curves showed linear elasticity, work hardening, necking, and fracture at each strain rate level. Flow stress and true failure strain both increased with increasing strain rate.
MECHANICS OF MATERIALS
(2021)
Article
Materials Science, Composites
Jichong Wang, Helezi Zhou, Zhengkun Liu, Xiongqi Peng, Huaming Zhou
Summary: The mechanical properties of natural fiber yarns, influenced by factors such as fiber length, fiber strength, and fiber quantity, exhibit randomness. An analytical model based on statistical theory accurately predicts the tensile properties of yarns, which is of significant importance for manufacturing and design processes.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Construction & Building Technology
Haifeng Yang, Jiankai Fang, Jiasheng Jiang, Minghui Li, Junjie Mei
Summary: By using recycled coarse aggregate (RCA) substitution rate and repeated load amplitude (LA) as parameters, the stress-strain curve tests of recycled aggregate concrete (RAC) specimens were conducted under constant repeated loading and varying repeated loading. The effects of RCA substitution rate and LA on the mechanical properties of concrete were analyzed, and the relationship between the mechanical parameters and repetitive LA was established. The equations for loading and unloading strain and the stress-strain curve under repetitive load were derived. The results showed that the peak stress of RAC decreased and the peak strain increased with the increase of LA, while the elastic modulus decreased linearly with LA.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Materials Science, Composites
Tuyet Nhi Lam, Geon Seok Lee, Bogyeong Kim, Hiep Dinh Xuan, Dowan Kim, Seong Il Yoo, Jinhwan Yoon
Summary: In this study, mechanically tough and stretchable elastomer microfibers were prepared using a microfluidic device, leading to strain sensors with high stretchability, wide sensing range, high linearity, low response time, and high resolution. The inclusion of PEDOT:PSS as bridges connecting CNTs improved the conductivity and linearity of the sensor, allowing for real-time detection of various human motions.
COMPOSITES SCIENCE AND TECHNOLOGY
(2021)
Article
Crystallography
Ishaq I. Alahmed, Sameh M. Altanany, Ismail Abdulazeez, Hassan Shoaib, Abduljabar Q. Alsayoud, Adel Abbout, Qing Peng
Summary: Graphene is a type of 2D material with unique properties and promising applications. In this study, the mechanical properties of triangular-cracked single-layer graphene were investigated through molecular dynamics simulations. The crack angle was found to have a significant impact on the mechanical properties, while variations in crack shape, size, and system size had minor effects. The elastic characteristics, including fracture toughness, were remarkably influenced by variations in strain rate.
Article
Metallurgy & Metallurgical Engineering
Dong-yong Wang, Xi Chen, Sheng-bin Jiang, Ji-lin Qi, Li-yun Peng
Summary: This paper introduces a penalty-based couple stress finite element method and studies its performance through numerical examples. The results show that this method has good performance in stress concentration analysis and strain localization analysis, and can effectively alleviate or eliminate the mesh-dependent problem in conventional finite element methods.
JOURNAL OF CENTRAL SOUTH UNIVERSITY
(2022)
Article
Engineering, Biomedical
Ligia Figueiredo, Afonso V. L. Gregorio, Alexandra Rodrigues, Pedro A. R. Rosa
Summary: Chitosan has attracted significant interest in the scientific community due to its distinctive properties, with researchers attempting to produce dense chitosan materials by blending with additives and ceramic particles, and evaluating their mechanical behavior through compression tests. The results show promising potential for future applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Ji Qi, Yuan Zhang, Huan Liu, Hang Xu, Chen Wang, Linglong Hu, Ming Feng, Weiming Lu
Summary: In this study, the effects of strain on the oxygen evolution reaction (OER) performance were investigated using different types of strain. It was found that the strain exhibited different trends in rigid and flexible materials, which can be explained by the difference in oxygen activation energy in lattice fields.
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, Choy Lin Lee, Golnaz Sarfarazi, Bradley Xue, Roy Judge, Ivan Darby
Summary: This study compared the 2-year clinical performance of restoring single dental implants using the Encode and conventional protocols. Both protocols showed similar outcomes in terms of patient satisfaction, esthetics, prosthesis cleansability, mucosal health, and other variables. Screw loosening and ceramic chipping were minor issues observed in both protocols, with higher survival rates in the Encode group.
JOURNAL OF ORAL IMPLANTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, Roy Judge
Summary: This study found that vertical misfit in implant frameworks is associated with less screw stability and more implant displacement. Retightening the retaining screws during bone maturation seems to help maintain torque values.
JOURNAL OF ORAL IMPLANTOLOGY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Vanya Rasaie, Jaafar Abduo, Saloumeh Hashemi
Summary: This study systematically reviewed clinical and laboratory studies on the accuracy of intraoral scanners in recording denture bearing areas. The results showed that while intraoral scanners were comparable to conventional techniques in recording bony structures, they had limitations in accurately registering mobile tissues. Factors such as presence of a marker, larger scanner head size, and specific scanning techniques appeared to improve the accuracy of digital impressions.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, Douglas Lau
Summary: In this study, it was found that fully-guided placement was significantly more accurate than pilot-guided and freehand placements for novice clinicians. Pilot-guided placement was more accurate than freehand placement for horizontal platform and apex deviations, as well as interimplant distance deviation. Fully-guided placement showed consistent accuracy regardless of implant location or horizontal deviations of the platform and apex.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Kritesh Bhai, Roy Judge, Jaafar Abduo, Joseph Palamara
Summary: The purpose of this observational clinical study was to measure the magnitude, direction, duration, and rate of tooth movement occurring in patients undergoing treatment using the Dahl principle. The results showed that tooth movement has a 3-dimensional nature and occlusal reestablishment mainly occurred via a combination of extrusive and intrusive movements. The study highlighted the advantages of digital technology in quantifying changes in patients undergoing treatment.
JOURNAL OF PROSTHETIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, Joseph E. A. Palamara
Summary: The study found that digital impressions tend to provide more accurate outcomes for trueness, precision, and angle deviation compared to conventional impressions. The NSP conventional impression technique showed inferior results compared to the SP technique, particularly for models with divergent implants. The True Definition system was generally the least accurate among all the IOS systems, especially for inter-implant distance deviation.
INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, Douglas Lau
Summary: In this study, fully guided and pilot-guided implant placements reduced the duration of implant placement compared to freehand placement for postgraduate students with minimal implant experience. Fully guided placement was consistently more accurate than pilot-guided placement.
EUROPEAN JOURNAL OF DENTAL EDUCATION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Varun Garg, Roy B. Judge, Jaafar Abduo, Joseph E. A. Palamara
Summary: This study evaluated the effect of hydrothermal aging on the load to failure and number of cycles to failure of implant-supported monolithic zirconia molar crowns under cyclic loading. The results showed that aging did not have a significant impact on these two parameters. Therefore, the clinical application of implant-supported monolithic zirconia crowns to replace missing molars seems reasonable.
INTERNATIONAL JOURNAL OF PROSTHODONTICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Nimra Tahir, Jaafar Abduo
Summary: This study evaluated the effect of different 3D printing orientations on the accuracy of implant surgical templates fabricated by a DLP printer. The results showed that horizontally printed templates exhibited the highest accuracy, and it is recommended to print the surgical templates with their largest dimension parallel to the printing platform.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, David Laskey
Summary: The type of preparation affects the accuracy of IOS systems, with smaller and simpler preparations having higher accuracy. The proximal areas are more susceptible to errors regardless of the preparation type, highlighting the importance of easier accessibility for scanning.
JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY
(2022)
Review
Multidisciplinary Sciences
Jaafar Abduo, Douglas Lau
Summary: This study aimed to evaluate the prevalence, risk factors, and implications of proximal contact loss (PCL) between implant prostheses and natural teeth. The study found that PCL is frequent, inevitable, and progressive. The duration of service and the location of proximal contacts were identified as influencing factors. Food impaction was a common implication of PCL. However, further research is needed to understand the influence of prosthesis design on PCL.
Article
Dentistry, Oral Surgery & Medicine
Jaafar Abduo, Grace Ho, Alannah Centorame, Simran Chohan, Clara Park, Ramiz Abdouni, Phillip Le
Summary: This study compared the marginal accuracy of zirconia crowns fabricated using different workflows and designs. The results showed that digitally fabricated veneered zirconia crowns had superior marginal accuracy compared to conventionally fabricated monolithic zirconia crowns. Buccal veneering improved the vertical and horizontal marginal accuracies of the crowns.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2023)
Article
Nanoscience & Nanotechnology
Karolinne Martins de Sousa, Denver P. Linklater, Billy J. Murdoch, Mohammad Al Kobaisi, Russell J. Crawford, Roy Judge, Stuart Dashper, Alastair J. Sloan, Dusan Losic, Elena P. Ivanova
Summary: In this study, a multiscale titanium surface topography was developed to promote osteogenic and mechano-bactericidal activity. The results showed that the micronanostructured surfaces enhanced MG-63 attachment and differentiation, and exhibited a high level of bactericidal activity.
ACS APPLIED BIO MATERIALS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Ramadhan Hardani Putra, Upul Cooray, Aga Satria Nurrachman, Nobuhiro Yoda, Roy Judge, Dina Karimah Putri, Eha Renwi Astuti
Summary: This study systematically evaluated the correlation between alveolar bone parameters (bone density and cortical bone thickness) and primary implant stability. The results demonstrated a significant association between alveolar bone condition and primary implant stability. Low bone density and thin cortical bone may result in low primary implant stability.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Efthimios Gazelakis, Roy B. Judge, Joseph E. A. Palamara, Mohsin Nazir
Summary: The aim of this study was to investigate the cortical peri-implant strains generated by an osseo-integrated rectangular block implant (RBI), and to relate these findings to known human physiological parameters. The results showed that the applied off-axial loads resulted in a heterogeneous pattern of bucco-lingual and mesio-distal cortical strains, both vertically and horizontally. The short dimensioned osseo-integrated RBI design appeared to biomechanically withstand the applied loads and maintain the strains generated within physiological limits. Further studies and statistical analyses are needed to confirm these findings.
BIOENGINEERING-BASEL
(2022)
