Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells

The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells

(2011) K. Zitzmann et al.   ENDOCRINE-RELATED CANCER

The molecular pathogenesis and management of bronchial carcinoids

(2011) Mehtap Cakir et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Therapeutic strategies for advanced neuroendocrine carcinomas of jejunum/ileum and pancreatic origin

(2011) C. J. Auernhammer et al.   GUT

Nordic Guidelines 2010 for diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours

(2010) Eva Tiensuu Janson et al.   ACTA ONCOLOGICA

Compensatory activation of Akt in response to mTOR and Raf inhibitors – A rationale for dual-targeted therapy approaches in neuroendocrine tumor disease

(2010) Kathrin Zitzmann et al.   CANCER LETTERS

Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy

(2010) James R Porter et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Molecular markers for novel therapies in neuroendocrine (carcinoid) tumors

(2010) Judith A Gilbert et al.   ENDOCRINE-RELATED CANCER

Mechanistic Evaluation of the Novel HSP90 Inhibitor NVP-AUY922 in Adult and Pediatric Glioblastoma

(2010) N. Gaspar et al.   MOLECULAR CANCER THERAPEUTICS

Update on Hsp90 Inhibitors in Clinical Trial

(2009) Y. Kim et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

To fold or not to fold: modulation and consequences of Hsp90 inhibition

(2009) Laura B Peterson et al.   Future Medicinal Chemistry

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

(2008) S. A. Eccles et al.   CANCER RESEARCH

One Hundred Years After “Carcinoid”: Epidemiology of and Prognostic Factors for Neuroendocrine Tumors in 35,825 Cases in the United States

(2008) James C. Yao et al.   JOURNAL OF CLINICAL ONCOLOGY

Gastroenteropancreatic neuroendocrine tumours

(2008) Irvin M Modlin et al.   LANCET ONCOLOGY

Signalling profile and antitumour activity of the novel Hsp90 inhibitor NVP-AUY922 in multiple myeloma

(2008) T Stühmer et al.   LEUKEMIA

Neuroendocrine tumors of the gastro-entero-pancreatic system

(2008) Sara Massironi et al.   WORLD JOURNAL OF GASTROENTEROLOGY