Article
Medicine, General & Internal
Malia S. Q. Murphy, Robin Ducharme, Steven Hawken, Daniel J. Corsi, William Petrcich, Darine El-Chaar, Lise Bisnaire, Daniel I. McIsaac, Deshayne B. Fell, Shi Wu Wen, Mark C. Walker
Summary: This study found that intrapartum epidural analgesia was associated with a small increase in the risk of ASD in offspring. However, the biological plausibility of this association remains unclear, and caution should be exercised when interpreting the findings.
Article
Pharmacology & Pharmacy
Wenping Xu, Dan Michael Drzymalski, Ling Ai, Hanqing Yao, Lin Liu, Fei Xiao
Summary: The initial infusion dose of 0.1 µg/kg/min of norepinephrine was effective in preventing spinal anesthesia-induced hypotension.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Hiroshi Yonekura, Yusuke Mazda, Shohei Noguchi, Hironaka Tsunobuchi, Motomu Shimaoka
Summary: The study aimed to investigate the practice of general anesthesia for cesarean delivery in Japan using a nationwide claims database. The results showed a gradual decrease in the use of general anesthesia over a 15-year period, regardless of the definition used. The authors recommend using a combination of claim code L008 and muscle relaxant use as the clinical definition of general anesthesia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Medicinal
Wan-Yi Rao, Fang Xu, Shao-Bing Dai, Zhong Mei, Xiao-Ping Chen, Chang-Cheng Lv, Chun-Lei Liu, Warwick Ngan Kee, Xin-Zhong Chen
Summary: This study compared three different anesthesia techniques and found that DPE anesthesia had a faster onset, shorter duration of surgical sensory block, lower incidence of intraoperative pain, and higher patient satisfaction compared to EA anesthesia. Additionally, DPE anesthesia had less impact on maternal hemodynamic parameters compared to CSE anesthesia, suggesting its effectiveness in obstetric surgery.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2023)
Article
Medicine, General & Internal
Jiangling Wang, Yajian Shen, Wenjing Guo, Wen Zhang, Xiaoying Cui, Shunv Cai, Xinzhong Chen
Summary: This study found that combined epidural anesthesia can reduce the required drug concentration for achieving loss of consciousness, decrease the consumption of anesthetics, and hasten recovery from anesthesia.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, General & Internal
Rachel J. Kearns, Martin Shaw, Piotr S. Gromski, Stamatina Iliodromiti, Deborah A. Lawlor, Scott M. Nelson
Summary: This population-based cohort study in Scotland found that labor epidural analgesia was not independently associated with adverse neonatal or childhood development outcomes. Associations with neonatal resuscitation and admission were likely mediated by mode of delivery.
Article
Chemistry, Medicinal
Xiaofei Mo, Tianyun Zhao, Jinghui Chen, Xiang Li, Jun Liu, Cuiyi Xu, Xingrong Song
Summary: Programmed intermittent epidural bolus provides more effective pain relief and less motor block after cesarean section, without an increased risk of urinary retention and blood pressure instability.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Medicine, General & Internal
Allison Lee, Jean Guglielminotti, Anne-Sophie Janvier, Guoha Li, Ruth Landau
Summary: This study evaluates the association of race and ethnicity with the provision and timing of epidural blood patch (EBP) for management of postdural puncture headache in obstetric patients. The study finds significant racial and ethnic disparities, with lower rates and delayed timing of EBP among certain groups.
Article
Obstetrics & Gynecology
Chan Shen, Lin Chen, Chengjin Yue, Jing Cheng
Summary: This study investigated the effectiveness of extending epidural analgesia for intrapartum cesarean section. The results showed that using a well-functioning epidural catheter for extending epidural analgesia may be a reliable and effective anesthetic method.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Review
Obstetrics & Gynecology
Pan Li, Xiaoting Ma, Shuang Han, Izumi Kawagoe, Kurt Ruetzler, Amos Lal, Longlu Cao, Ran Duan, Jianli Li
Summary: This study aims to provide an updated analysis of the incidence of conversion from epidural analgesia to general anesthesia and to evaluate and analyze potential risk factors contributing to the failure of this transition. The study found that the overall incidence of conversion was 6% and identified several factors associated with the failure group, including higher rates of incomplete block, emergency cesarean sections, provision of anesthesia by non-obstetric anesthesiologists, higher dosage of epidural administration, and greater height.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Review
Medicine, General & Internal
Dingfeng Zhang, Stephanie-May Ruchat, Cristina Silva-Jose, Javier Gil-Ares, Ruben Barakat, Miguel Sanchez-Polan
Summary: This article aimed to investigate the effect of physical activity during pregnancy on the type of delivery, the duration of labor, and the use of epidurals. The study found that physical activity during pregnancy can reduce the risk of cesarean section and instrumental delivery, as well as shorten the duration of the first stage of labor.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Fangfang Miao, Kunpeng Feng, Xuexin Feng, Long Fan, Yu Lang, Qingfang Duan, Ruixue Hou, Di Jin, Tianlong Wang
Summary: This study investigated the optimal concentrations of ropivacaine and sufentanil for controlling postoperative pain after cesarean section. The results showed that the combination of 0.15% ropivacaine and 0.5 mu g/ml sufentanil administered epidurally led to lower pain scores, improved patient satisfaction, and shorter time to first flatus, but also increased the incidence of pruritus and numbness.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Fei Xiao, Wen-Ping Xu, Han-Qing Yao, Jia-Ming Fan, Xin-Zhong Chen
Summary: The study aimed to determine the median effective dose (ED50) and 90% effective dose (ED90) of weight-based fixed-rate metaraminol infusions for preventing spinal-anesthesia-induced hypotension in Cesarean delivery. The results showed that as the infusion rate of metaraminol increased, the incidence of hypotension decreased, but the risk of reactive hypertension increased.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Sheng-You Wang, Yan He, Hai-Juan Zhu, Bo Han
Summary: The dural puncture epidural (DPE) technique provides higher-quality anesthesia, with a rapid onset of surgical anesthesia, better cranial and sacral sensory block spread, and a higher motor block degree, without increasing the incidence of maternal or fetal side effects in patients undergoing repeat cesarean delivery.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Health Care Sciences & Services
Ruben Kovac, Ivo Juginovic, Nikola Delic, Ivan Velat, Hrvoje Vucemilovic, Ivan Vukovic, Verica Kozomara, Bozidar Duplancic
Summary: This study compared the quality of recovery after open radical prostatectomy between two groups of patients. The results showed no significant difference in recovery between the group receiving epidural anesthesia and analgesia and the group receiving intravenous analgesia.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Anesthesiology
Vesela P. Kovacheva, Mieke A. Soens, Lawrence C. Tsen
Article
Anesthesiology
H. P. Sviggum, S. Yacoubian, X. Liu, L. C. Tsen
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
(2015)
Article
Anesthesiology
Brian T. Bateman, Lawrence C. Tsen, Jun Liu, Alexander J. Butwick, Krista F. Huybrechts
ANESTHESIA AND ANALGESIA
(2014)
Article
Anesthesiology
Steven Lipman, Sheila Cohen, Sharon Einav, Farida Jeejeebhoy, Jill M. Mhyre, Laurie J. Morrison, Vern Katz, Lawrence C. Tsen, Kay Daniels, Louis P. Halamek, Maya S. Suresh, Julie Arafeh, Dodi Gauthier, Jose C. A. Carvalho, Maurice Druzin, Brendan Carvalho
ANESTHESIA AND ANALGESIA
(2014)
Article
Anesthesiology
Roulhac D. Toledano, Lawrence C. Tsen
Editorial Material
Anesthesiology
Brian T. Bateman, Lawrence C. Tsen
Article
Anesthesiology
Jill M. Mhyre, Lawrence C. Tsen, Sharon Einav, Elena V. Kuklina, Lisa R. Leffert, Brian T. Bateman
Review
Anesthesiology
Anthony Chau, Lawrence C. Tsen
CURRENT OPINION IN ANESTHESIOLOGY
(2014)
Article
Anesthesiology
V. P. Kovacheva, M. A. Soens, L. C. Tsen
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
(2013)
Review
Anesthesiology
S. Orbach-Zinger, A. Jadon, D. N. Lucas, A. T. Sia, L. C. Tsen, M. Van de Velde, M. Heesen
Summary: In cases of accidental dural puncture, inserting an intrathecal catheter can provide rapid labour analgesia and anaesthesia for caesarean section, but careful management and adherence to aseptic technique are crucial to prevent complications. Institutions should establish protocols and monitor closely when using intrathecal catheters with different medications for various scenarios.
Article
Multidisciplinary Sciences
Holly B. Ende, Ruth Landau, Naida M. Cole, Sara M. Burns, Brian T. Bateman, Melissa E. Bauer, Jessica L. Booth, Pamela Flood, Lisa R. Leffert, Timothy T. Houle, Lawrence C. Tsen
Summary: The study found that women with intrapartum cesarean delivery experienced higher pain scores on the day of surgery, increased opioid use after discharge, but similar pain scores at other time points compared to women without labor prior to cesarean delivery.
Letter
Anesthesiology
S. C. Reale, M. I. Lumbreras-Marquez, E. Krupat, L. C. Tsen
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
(2022)
Review
Anesthesiology
L. C. Tsen, S. Gelman
Summary: Maternal positioning, medications, and other modulations can influence the well-being of both the mother and fetus. Understanding the role of the venous system is crucial in considering the effects of hypotension, hypertension, and fluid management during pregnancy.
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
(2022)
Article
Health Care Sciences & Services
Jo Shapiro, Anthony Whittemore, Lawrence C. Tsen
JOINT COMMISSION JOURNAL ON QUALITY AND PATIENT SAFETY
(2014)
Article
Anesthesiology
Mrinalini Balki, Lawrence Tsen
INTERNATIONAL ANESTHESIOLOGY CLINICS
(2014)