4.5 Review

The mechanism of weight loss with laparoscopic adjustable gastric banding: induction of satiety not restriction

期刊

INTERNATIONAL JOURNAL OF OBESITY
卷 35, 期 -, 页码 S26-S30

出版社

NATURE PUBLISHING GROUP
DOI: 10.1038/ijo.2011.144

关键词

satiety; esophageal motility; bariatric surgery; mechanism; laparoscopic adjustable gastric band

资金

  1. Allergan

向作者/读者索取更多资源

Laparoscopic adjustable gastric banding (LAGB) has rapidly emerged as a popular bariatric procedure because of its safety, efficacy, durability and adjustability. Despite widespread use, there is limited understanding of how it induces weight loss. Previously, it has been classified as a restrictive procedure, physically limiting the patient to a small meal that subsequently slowly empties into the distal stomach. However, the tiny pouch of stomach created above the LAGB appears to be unable to accommodate even the smallest of meals. Therefore, the key mechanism has been hypothesized to be the induction of satiety via, as yet, undefined pathways. The critical question remains: what are the key physiological changes that lead to satiety and weight loss? In successful LAGB patients, a consistent intraluminal pressure at the level of the LAGB of 26.9 +/- 19.8 mm Hg is observed. Studies using semi-solid swallows combined with intraluminal pressure recordings have demonstrated that semi-solid transit across the resistance of the LAGB is mediated by repeated esophageal peristaltic contractions (mean 4.5 +/- 2.9) that produce episodic flow, interspersed by reflux events. Failed transit results in obstruction and regurgitation, whereas dilatation of the supraband stomach induces severe and intolerable reflux. Overall gastric emptying does not appear to be significantly altered following LAGB. Focused investigations have shown that the supraband stomach is empty of an ingested meal 1-2 min after intake ceases. Considerable progress has been made in understanding the mechanical physiological effects of the LAGB on esophageal and proximal gastric function. These have been correlated with patient outcomes and sensations. On the basis of recent data, it appears that the LAGB activates the peripheral satiety mechanism without physically restricting the meal size. Therefore, it should not be classified as a restrictive procedure. The precise mechanism of weight loss with the LAGB remains to be delineated. International Journal of Obesity (2011) 35, S26-S30; doi:10.1038/ijo.2011.144

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Surgery

Evaluation of the histological variability of core and wedge biopsies in nonalcoholic fatty liver disease in bariatric surgical patients

Geraldine J. Ooi, Andrew Clouston, Yazmin Johari, William W. Kemp, Stuart K. Roberts, Wendy A. Brown, Paul R. Burton

Summary: Liver biopsy remains the gold standard for characterizing and evaluating treatment response in nonalcoholic fatty liver disease (NAFLD), but there is variability in individual components such as fibrosis stage between different biopsy sites. Clinicians should consider biopsies from varied sites to better assess liver disease severity, as a combination of biopsy techniques improves the detection of pathology.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2021)

Review Surgery

Systematic review of perioperative mortality risk prediction models for adults undergoing inpatient non-cardiac surgery

Jennifer R. Reilly, Belinda J. Gabbe, Wendy A. Brown, Carol L. Hodgson, Paul S. Myles

Summary: This study evaluated perioperative mortality risk prediction tools relevant to an Australian context and identified four potential tools for adaptation, including SMPM, POSPOM, SORT, and NZRISK. SORT and NZRISK may provide an opportunity to simultaneously investigate and develop a locally valid perioperative mortality risk prediction model with high predictive performance.

ANZ JOURNAL OF SURGERY (2021)

Article Gastroenterology & Hepatology

Fit-for-Discharge Criteria after Esophagectomy: An International Expert Delphi Consensus

P. C. Mueller, J. R. Kapp, D. Vetter, L. Bonavina, W. Brown, S. Castro, E. Cheong, G. E. Darling, J. Egberts, L. Ferri, S. S. Gisbertz, I Gockel, P. P. Grimminger, W. L. Hofstetter, A. H. Hoelscher, D. E. Low, M. Luyer, S. R. Markar, S. P. Moenig, K. Moorthy, C. R. Morse, B. P. Mueller-Stich, P. Nafteux, A. Nieponice, G. A. P. Nieuwenhuijzen, M. Nilsson, C. Palanivelu, P. Pattyn, M. Pera, J. Rasanen, U. Ribeiro, C. Rosman, W. Schroeder, B. Sgromo, M. van Berge Henegouwen, R. van Hillegersberg, H. van Veer, F. van Workum, D. Watson, B. P. L. Wijnhoven, C. A. Gutschow

Summary: This study achieved international consensus on criteria for hospital discharge after esophagectomy through a 3-round Delphi process involving 40 esophageal surgeons from 16 countries and 4 continents. The consensus included criteria related to nutrition, gas passage, removal of central venous catheters, and use of adequate analgesia. These standardized endpoints can serve as objective measures for short-term recovery and assist in making decisions about patient discharge to reduce the risk of premature discharge or prolonged admission.

DISEASES OF THE ESOPHAGUS (2021)

Article Surgery

Mechanisms of Esophageal and Gastric Transit Following Sleeve Gastrectomy

Yazmin Johari, Anagi Wickremasinghe, Pradipta Kiswandono, Helen Yue, Geraldine Ooi, Cheryl Laurie, Geoffrey Hebbard, Paul Beech, Kenneth Yap, Wendy Brown, Paul Burton

Summary: Following sleeve gastrectomy, esophago-gastric transit is primarily driven by isobaric pressurization of the stomach induced by repeated esophageal peristaltic contractions, with a strong association with reflux. Transit of food from the esophagus to the small bowel post-operatively is rapid and substantial.

OBESITY SURGERY (2021)

Article Surgery

Pathophysiological Mechanisms of Gastro-esophageal Reflux After Sleeve Gastrectomy

Yazmin Johari, Gillian Lim, Anagi Wickremasinghe, Helen Yue, Jarrel Seah, Geraldine Ooi, Julie Playfair, Cheryl Laurie, Paul Beech, Kenneth Yap, Geoff Hebbard, Wendy Brown, Paul Burton

Summary: The study evaluated the mechanisms associated with reflux events after sleeve gastrectomy (SG). The results showed a strong association between reflux and SG, and identified three unique categories of reflux. The study also found that elevated gastro-esophageal pressure gradient was the main mechanism of reflux.

ANNALS OF SURGERY (2022)

Article Surgery

A 4-tier Protocolized Radiological Classification System for Leaks Following Sleeve Gastrectomy

Yazmin Johari, William Catchlove, Madeleine Tse, Kalai Shaw, Eldho Paul, Richard Chen, Damien Loh, Andrew Packiyanathan, Paul Burton, Peter Nottle, Samantha Ellis, Wendy Brown

Summary: In this study, a classification system based on CT findings was developed to predict the outcomes of sleeve gastrectomy leaks. The system showed good agreement and could help guide patient management and interventions.

ANNALS OF SURGERY (2022)

Article Surgery

Expected Values of Esophageal Transit and Gastric Emptying Scintigraphy Post-uncomplicated Sleeve Gastrectomy

Yazmin Johari, Helen Yue, Cheryl Laurie, Geoffrey Hebbard, Paul Beech, Kenneth Sk Yap, Wendy Brown, Paul Burton

Summary: This study found that rapid gastric emptying and common esophageal reflux events are common in post-SG patients without complications. Expected values for esophageal transit and gastric emptying in asymptomatic post-SG patients were defined.

OBESITY SURGERY (2021)

Article Anesthesiology

Towards a national perioperative outcomes registry: A survey of perioperative electronic medical record utilisation to support quality assurance and research at Australian and New Zealand College of Anaesthetists Clinical Trials Network hospitals in Australia

Jennifer R. Reilly, Carolyn Deng, Wendy A. Brown, Dianne Brown, Belinda J. Gabbe, Carol L. Hodgson, Paul S. Myles

Summary: In Australia, there is a need to improve the utilization of perioperative electronic medical record data. Establishing a national perioperative outcomes registry can help address the gap in data utilization and facilitate multicenter research and quality assurance.

ANAESTHESIA AND INTENSIVE CARE (2022)

Article Surgery

Low muscularity increases the risk for post-operative pneumonia and delays recovery from complications after oesophago-gastric cancer resection

Lisa C. Murnane, Adrienne K. Forsyth, Jim Koukounaras, Charles H. C. Pilgrim, Kalai Shaw, Wendy A. Brown, Marina Mourtzakis, Audrey C. Tierney, Paul R. Burton

Summary: Low skeletal muscle index (SMI) is associated with an increased risk of post-operative pneumonia and longer length of stay (LOS) for patients with complications, but not with 5-year overall or disease-free survival after oesophago-gastric cancer surgery. Assessment of muscle mass may require additional measures to enhance preoperative risk assessment.

ANZ JOURNAL OF SURGERY (2021)

Review Surgery

Clinical quality registries: urgent reform is required to enable best practice and best care

Wendy A. Brown, Susannah Ahern, Andrew D. MacCormick, Jennifer R. Reilly, Julian A. Smith, David A. Watters

Summary: Clinical quality registries (CQRs) are tools that systematically collect data to assess the quality of care. Despite successful examples in Australia and New Zealand, there are still significant barriers to the implementation and function of CQRs, including challenges in data capture, ethical review, and funding.

ANZ JOURNAL OF SURGERY (2022)

Article Surgery

Initial radiologic appearance rather than management strategy predicts the outcomes of sleeve gastrectomy leaks

William Catchlove, Yazmin Johari, Edward Forrest, Amos Au, Kalai Shaw, Peter Nottle, Samantha Ellis, Wendy A. Brown, Paul Burton

Summary: This study compared the treatment methods for sleeve gastrectomy leaks and found no significant difference in outcomes between intraluminal occlusion and repeated debridement. The initial radiologic appearance was predictive of length of stay and complication severity.

SURGERY FOR OBESITY AND RELATED DISEASES (2022)

Article Surgery

External validation of a surgical mortality risk prediction model for inpatient noncardiac surgery in an Australian private health insurance dataset

Jennifer Richelle Reilly, Darren Wong, Wendy Ann Brown, Belinda Jane Gabbe, Paul Stewart Myles

Summary: This study aimed to investigate the external validity of Surgical Outcome Risk Tool (SORT) in predicting in-hospital mortality in the Australian context. The results showed that SORT may significantly under-predict 30-day mortality in a dataset with low perioperative mortality rate.

ANZ JOURNAL OF SURGERY (2022)

Review Surgery

Victoria's surgical response to the COVID-19 pandemic: the first two years

Henry Richard Edward Drysdale, David Allan Watters, Yit Leang, Benjamin N. J. Thomson, Wendy Ann Brown, Andrew Wilson, Victorian Surgical Directors Grp

Summary: Victoria experienced three major waves of COVID-19, with Melbourne being locked down for 267 days. The state implemented strict social restrictions, contact tracing, furlough, escalating PPE guidance, and respiratory protection measures, which effectively reduced healthcare worker infections.

ANZ JOURNAL OF SURGERY (2023)

Article Surgery

The length of hospital stay following bariatric surgery in Australia: the impact of patient, procedure, system and surgeon

Chiara Chadwick, Paul R. R. Burton, Dianne Brown, Jennifer F. F. Holland, Angus Campbell, Jenifer Cottrell, Jennifer Reilly, Andrew D. D. MacCormick, Ian Caterson, Wendy A. A. Brown

Summary: This study aimed to define the expected average length of stay (ALOS) of bariatric surgery in Australia and to identify factors that influence ALOS. The study found that increased patient age, diabetes, rural living, procedural complications, and surgeon and hospital case volume all contributed to a small increase in ALOS following bariatric surgery.

ANZ JOURNAL OF SURGERY (2023)

Article Surgery

The National Aeronautics and Space Administration-task load index: NASA-TLX: evaluation of its use in surgery

Stephen W. Bell, Joseph C. H. Kong, David A. Clark, Peter Carne, Stewart Skinner, Stephen Pillinger, Paul Burton, Wendy Brown

Summary: This study evaluated the NASA Task Load Index (TLX) as an objective measure of technical difficulty of an operation. The results showed that the NASA TLX score correlated significantly with operative duration, blood loss, previous abdominal surgery, and the surgeon's assessment of difficulty. This tool could be used in research and teaching settings to assess surgical difficulty and monitor a trainee's proficiency over time.

ANZ JOURNAL OF SURGERY (2022)

暂无数据