Article
Gastroenterology & Hepatology
Yiqing Wang, Yin Cao, Benjamin Lebwohl, Mingyang Song, Qi Sun, Peter H. R. Green, Edward L. Giovannucci, Walter C. Willett, Andrew T. Chan
Summary: The study found that gluten intake was not associated with the risk of digestive system cancers in adults without celiac disease, indicating that restricting dietary gluten may not be beneficial for the prevention of digestive system cancers in the general population.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Chemistry, Applied
Mengzhen Ding, Zixin Huang, Zhiying Jin, Chang Zhou, Juqing Wu, Di Zhao, Kai Shan, Weixin Ke, Miao Zhang, Yingqun Nian, Chunbao Li
Summary: A high-fat diet can affect the solubility and secondary structures of proteins, as well as the microstructure of different protein types. Protein digestibility is influenced by protein type and fat content.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Beck A. Wehrle, Donovan P. German
Summary: Digestion and assimilation of nutrients and energy are crucial for survival. However, studies on digestive efficiency in reptiles are varied and may not always yield reliable results. This review examines common themes in reptilian digestive efficiency and proposes the use of non-ratio data for analysis. It also suggests employing consistent methodology and including a more diverse population in future studies.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2023)
Article
Nutrition & Dietetics
Xiaohua Huang, Yong Zhuo, Dandan Jiang, Yingguo Zhu, Zhengfeng Fang, Lianqiang Che, Yan Lin, Shengyu Xu, Lun Hua, Yuanfeng Zou, Chao Huang, Lixia Li, De Wu, Bin Feng
Summary: Maternal low-protein diet during puberty and adulthood may disrupt metabolic gene expression in the liver of offspring and exacerbate insulin resistance and hepatic steatosis in offspring fed a high-fat diet.
Review
Endocrinology & Metabolism
Alessandro Laviano
Summary: Recent advances suggest that protein intake plays a significant role in the nutritional management of patients with digestive cancers. High protein diets, mainly based on animal proteins, should be recommended to maintain nutritional status and achieve clinical benefits.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
(2022)
Review
Physiology
Yiwei Xiang, Dongdong Fan, Qimin An, Ting Zhang, Xianli Wu, Jianhong Ding, Xiaolin Xu, Gengyu Yue, Siqi Tang, Qian Du, Jingyu Xu, Rui Xie
Summary: Hypoxia is a state of oxygen limitation that mediates pathological processes and regulates physiological processes. Ion-transporting proteins control the flow of ions in cells and are regulated by hypoxia. Hypoxia-induced changes in ion-transporting proteins can lead to various diseases.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ameyalli M. Rodriguez-Cano, Isabel Gonzalez-Ludlow, Blanca Suarez-Rico, Araceli Montoya-Estrada, Omar Pina-Ramirez, Sandra B. Parra-Hernandez, Enrique Reyes-Munoz, Guadalupe Estrada-Gutierrez, Claudia C. Calzada-Mendoza, Otilia Perichart-Perera
Summary: This study found that consumption of ultra-processed food (UPF) during pregnancy may increase oxidative stress and is inversely associated with levels of oxidative stress markers in the body. Additionally, fiber intake was positively associated with protein carbonylation.
Review
Oncology
Mary Kay Washington, Richard M. Goldberg, George J. Chang, Paul Limburg, Alfred K. Lam, Manuel Salto-Tellez, Mark J. Arends, Iris D. Nagtegaal, David S. Klimstra, Massimo Rugge, Peter Schirmacher, Alexander J. Lazar, Robert D. Odze, Fatima Carneiro, Masashi Fukayama, Ian A. Cree
Summary: The WHO Classification of Tumours provides international standards for classification and diagnosis, with the latest fifth edition going digital and including a series of books. This article summarizes major diagnostic innovations from the past decade that have been incorporated into the classification.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Food Science & Technology
Ting-Ting Gao, Jing-Xue Liu, Xin Gao, Guo-Qi Zhang, Xiao-Zhi Tang
Summary: The stability and digestive properties of a dual-protein emulsion consisting of soy protein isolate (SPI) and whey protein isolate (WPI) were systematically studied. The particle size and viscosity of the dual-protein emulsion system decreased with an increase in WPI, likely due to the electric charge on the emulsion droplets. Emulsions with ratios of 3:7 and 5:5 exhibited the highest activity, and stability increased with increasing WPI. The study also found that WPI improved the antioxidant properties and nutritional value of the dual-protein emulsion.
Review
Public, Environmental & Occupational Health
Yujie Zhao, Junyi Zhan, Yongsen Wang, Dongli Wang
Summary: The meta-analysis showed that a plant-based diet is protective against digestive system cancers, including pancreatic, colorectal, rectal, and colon cancers. There was no significant difference between vegan and other plant-based diets in terms of cancer risk.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Erika Cortes-Macias, Marta Selma-Royo, Izaskun Garcia-Mantrana, Marta Calatayud, Sonia Gonzalez, Cecilia Martinez-Costa, Maria Carmen Collado
Summary: Maternal diet significantly impacts the composition and diversity of breast milk microbiota, with dietary fiber, plant, and animal protein intakes playing crucial roles. Mode of delivery and antibiotic exposure also influence breast milk microbiota, depending on the maternal dietary clusters. Further research is needed to understand the relationship between maternal diet and milk microbiota, as it has a significant impact on infant microbiota development and health outcomes.
JOURNAL OF NUTRITION
(2021)
Article
Endocrinology & Metabolism
Kosuke Shibamori, Yuki Kyoda, Tetsuya Shindo, Kohei Hashimoto, Ko Kobayashi, Toshiaki Tanaka, Hiromu Suzuki, Naoya Masumori
Summary: This study investigated the potential association between maternal nutrition and benign prostatic hyperplasia (BPH) using an animal experiment. The findings showed that a low protein diet promoted epithelial hyperplasia, while a high fat diet led to increased stromal growth.
Article
Biochemistry & Molecular Biology
Govindraj Ellur, Shinde Vijay Sukhdeo, Md Touseef Khan, Kunal Sharan
Summary: Maternal high protein diet results in reduced skeletal mineralization and bone mass in offspring through upregulation of miR-24-1-5p, which impairs osteoblast maturation.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Veterinary Sciences
Kikianne Kroeske, Ester Arevalo Sureda, Julie Uerlings, Dieter Deforce, Filip Van Nieuwerburgh, Marc Heyndrickx, Sam Millet, Nadia Everaert, Martine Schroyen
Summary: Maternal diet during late gestation can influence piglet metabolism, with different protein levels leading to differential gene expression in pathways related to metabolism and inflammation. The interaction between maternal and nursery diets highlights the potential for optimizing piglet metabolism through sow late gestation diet.
VETERINARY SCIENCES
(2021)
Article
Multidisciplinary Sciences
Oscar Bento Silva Neto, Rodrigo Valladao, Guilherme Rabelo Coelho, Renata Dias, Daniel Carvalho Pimenta, Adriana Rios Lopes
Summary: The digestive system of spiders is a rich source of new peptidase inhibitor molecules, including the inhibitor NcTI from Nephilingis cruentata, which has been identified as a member of the MIT1-like atracotoxin family and has trypsin inhibitory activity. This is the first time that this serine peptidase inhibitory function has been attributed to this structural family.
SCIENTIFIC REPORTS
(2023)
Review
Physiology
William Joyce, Tobias Wang
Summary: Acute exposure to low oxygen leads to conflicting demands on the heart, resulting in tachycardia or bradycardia. While mammals and fishes show different mechanisms in heart rate regulation during hypoxia, there are similarities in the underlying mechanisms. Bradycardia may primarily serve to protect the heart.
Editorial Material
Obstetrics & Gynecology
Stephen J. Simpson, David Raubenheimer, Kirsten I. Black, Arthur D. Conigrave
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Physiology
Vibeke S. S. Elbrond, Morten B. B. Thomsen, Jonas L. L. Isaksen, Ester D. D. Lunde, Stefano Vincenti, Tobias Wang, Jorgen Tranum-Jensen, Kirstine Calloe
Summary: The purpose of this study was to investigate and evaluate the relationship between the unique electrical axis pattern in the horse heart and the distribution and histology of the conduction system. The results showed that the direction of the electrical axis in the equine heart is determined by the structure of the intramural Purkinje fiber network, rather than being related to ventricular mass.
Article
Nutrition & Dietetics
Navoda Nirmani Liyanapathirana, Amanda Grech, Mengyu Li, Arunima Malik, Manfred Lenzen, David Raubenheimer
Summary: This study integrates input-output analysis and nutritional geometry to assess the sustainability of the Australian macronutrient dietary guidelines (AMDR). The study found that diets adhering to the guidelines were associated with moderate environmental and economic impacts. However, only about 20.42% of participants followed the guidelines. Encouraging the consumption of plant protein to meet the lower limit of recommended protein intake could improve dietary sustainability in Australia.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Ecology
Richard Grainger, Vincent Raoult, Victor M. Peddemors, Gabriel E. Machovsky-Capuska, Troy F. Gaston, David Raubenheimer
Summary: This study introduces a novel integration of stable isotopes and a multidimensional nutritional niche framework to explore individual diet specialisation in juvenile white sharks. The results show that white sharks are individual specialists within a generalist population niche, but their nutrient intake is consistent, suggesting they are nutritional specialists.
JOURNAL OF ANIMAL ECOLOGY
(2023)
Article
Nutrition & Dietetics
Nicholas A. Koemel, Alistair M. Senior, David S. Celermajer, Amanda Grech, Tim P. Gill, Stephen J. Simpson, David Raubenheimer, Michael R. Skilton
Summary: This study evaluated the associations between macronutrient intake and all-cause, cardiovascular, and cancer mortality. It found that a high-calorie diet consisting of moderately high protein, moderate fat, and moderate carbohydrate levels was associated with the highest mortality risk. Lower mortality risk was observed in two separate regions consisting of higher protein, higher carbohydrate, and lower fat levels or lower protein, moderate carbohydrate, and higher fat levels. These findings highlight the complex nonlinear and interactive association between macronutrients and all-cause mortality.
Article
Nutrition & Dietetics
Christoph Saner, Alistair M. Senior, Hanyue Zhang, Aino-Maija Eloranta, Costan G. Magnussen, Matthew A. Sabin, Markus Juonala, Marco Janner, David P. Burgner, Ursula Schwab, Eero A. Haapala, Berit L. Heitmann, Stephen J. Simpson, David Raubenheimer, Timo A. Lakka
Summary: This study tested for protein leverage and the protein leverage hypothesis in children and adolescents. The results showed that proportional energy intake of proteins was inversely associated with energy intake, and increased energy intake on diets with lower protein content was counterbalanced by increased energy expenditure and did not lead to increased adiposity.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Ecology
Robert Spitzer, Eric Coissac, Joris P. G. M. Cromsigt, Annika M. Felton, Christian Fohringer, Marietjie Landman, Wiebke Neumann, David Raubenheimer, Navinder J. Singh, Pierre Taberlet, Fredrik Widemo
Summary: Differences in botanical diet compositions correlated with nutritional differences in moose faecal samples collected during winter. Moose mixed Scots pine and Vaccinium spp. as complementary foods to reach a nutritional target resembling Salix spp. twigs and selected for Salix spp. browse. Available protein and total non-structural carbohydrates showed significant correlation in observed diets.
FUNCTIONAL ECOLOGY
(2023)
Editorial Material
Multidisciplinary Sciences
Bjarke Jensen, Antoon Fransiscus Maria Moorman, Tobias Wang, Peter Rask Moller, Jose Manuel Icardo, Henrik Lauridsen
Article
Genetics & Heredity
Javier Gomez Ortega, David P. Raubenheimer, Sonika P. Tyagi, Christen P. Mirth, Matthew D. W. P. Piper
Summary: Dietary nutrient composition plays a crucial role in shaping vital fitness traits and behaviors. Fruit flies, like Drosophila melanogaster, experience protein limitation at the level of amino acids. Despite significant differences in gene expression between male and female flies, their amino acid utilization patterns are remarkably conserved.
Article
Multidisciplinary Sciences
Simone K. A. Videsen, Malene Simon, Fredrik Christiansen, Ari Friedlaender, Jeremy Goldbogen, Hans Malte, Paolo Segre, Tobias Wang, Mark Johnson, Peter T. Madsen
Summary: Giant rorqual whales have a massive food turnover driven by a high-intake lunge feeding style, which is considered the largest biomechanical action. This feeding behavior, although high-drag, is energetically cheap, allowing rorquals to be flexible in exploiting different prey patches and resilient to environmental fluctuations and disturbance. As a result, the ecological role and food turnover of these marine giants are likely overestimated.
Article
Ecology
Jorin Veen, Haneul Jang, David Raubenheimer, Bryndan O. C. M. van Pinxteren, Vidrige Kandza, Patrick G. Meirmans, Nicole M. van Dam, Susanne Dunker, Petra Hoffmann, Anja Worrich, Karline R. L. Janmaat
Summary: The study examines the seasonal diet composition, foraging behavior, and botanical knowledge of Mbendjele BaYaka forager children in the Republic Congo. The results show that children's foraging behavior and botanical knowledge fluctuate with the seasons. The children spend more than half of their time foraging independently, predominantly collecting and eating fruits, tubers, and seeds. The study suggests that the foraging activities of BaYaka children facilitate the acquisition of foraging skills and botanical knowledge, and the transition to a horticultural lifestyle has significant consequences for their cognitive development.
FRONTIERS IN ECOLOGY AND EVOLUTION
(2023)
Article
Nutrition & Dietetics
Nicholas A. Koemel, Alistair M. Senior, Tarik Benmarhnia, Andrew Holmes, Mirei Okada, Youssef Oulhote, Helen M. Parker, Sanam Shah, Stephen J. Simpson, David Raubenheimer, Timothy P. Gill, Nasser Laouali, Michael R. Skilton
Summary: This study examined the role of gut microbiome metabolites in the relationship between diet quality and cardiometabolic health. The analysis of cross-sectional data from 4685 US adults revealed significant interactive associations between microbial lignan metabolites and several cardiometabolic health markers. These findings suggest that the gut microbiome may modulate the overall association of diet quality with cardiometabolic health.
Article
Nutrition & Dietetics
Jiabao Yan, Cuiru Ren, Yunlong Dong, Jibran A. A. Wali, Hongjie Song, Ying Zhang, Hengrui Zhang, Guangning Kou, David Raubenheimer, Zhenwei Cui
Summary: Ketogenic diet combined with moderate aerobic exercise effectively reduces body weight and fat mass, with no significant adverse effects except for an increase in circulating triglyceride level. Aerobic exercise further improves blood parameters and hepatic condition in mice fed with ketogenic diet.
Letter
Food Science & Technology
Mengyu Li, Manfred Lenzen, Arunima Malik, David Raubenheimer