Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder

The role of Cyclophilin D in learning and memory

(2010) Akihiro Mouri et al.   HIPPOCAMPUS

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

(2009) Elena Palma et al.   HUMAN MOLECULAR GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Phenomic, Convergent Functional Genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism

(2008) H. Le-Niculescu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Elevated Cerebrospinal Fluid Lactate Concentrations in Patients with Bipolar Disorder and Schizophrenia: Implications for the Mitochondrial Dysfunction Hypothesis

(2008) William T. Regenold et al.   BIOLOGICAL PSYCHIATRY

Increased expression of splicing factor SRp20 mRNA in bipolar disorder patients

(2008) Toshio Watanuki et al.   JOURNAL OF AFFECTIVE DISORDERS

The Mitochondrial Phosphate Carrier Interacts with Cyclophilin D and May Play a Key Role in the Permeability Transition

(2008) Anna W. C. Leung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

(2008) Manuel A R Ferreira et al.   NATURE GENETICS

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D

(2008) S. Luvisetto et al.   NEUROSCIENCE

Molecular neurobiology of bipolar disorder: a disease of ‘mood-stabilizing neurons’?

(2008) Tadafumi Kato   TRENDS IN NEUROSCIENCES

Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog

(2007) L.H. Mbye et al.   EXPERIMENTAL NEUROLOGY