4.3 Article

Biologically Active Benzimidazole Derivatives

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MINI-REVIEWS IN ORGANIC CHEMISTRY
卷 12, 期 2, 页码 178-195

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BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570193X1202150225153403

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Benzimidazole; biological activity; synthesis

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Benzimidazoles and its derivatives are an important group of heterocyclic compounds that show a wide range of pharmacological properties such as antitumor, antimicrobial, antihypertensive, antiviral, antiulcer, anticonvulsant, antiinflammatory activities etc. These diverse biological applications of benzimidazole compounds have motivated new efforts in search for novel derivatives with improved biological activity and diverse applications in pharmaceutical industry. Outstanding to the importance of this structure, the aim of this review is to highlight aspects reported on the chemistry and biological activity of benzimidazoles during the past few years (2000-2013).

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