New Insights into Functional Roles of the Polypyrimidine Tract-Binding Protein

A Polypyrimidine Tract-Binding Protein-Dependent Pathway of mRNA Stability Initiates with CpG Activation of Primary B Cells

(2014) J. F. Porter et al.   JOURNAL OF IMMUNOLOGY

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

(2013) Yuanchao Xue et al.   CELL

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

(2013) J. Ye et al.   JOURNAL OF CELL SCIENCE

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3

(2013) Clare Gooding et al.   NUCLEIC ACIDS RESEARCH

A Biophysical Model for Identifying Splicing Regulatory Elements and Their Interactions

(2013) Ji Wen et al.   PLoS One

Polypyrimidine Tract-Binding Protein Induces p19Ink4d Expression and Inhibits the Proliferation of H1299 Cells

(2013) Shankung Lin et al.   PLoS One

Polypyrimidine Tract Binding Protein-1 (PTB1) Is a Determinant of the Tissue and Host Tropism of a Human Rhinovirus/Poliovirus Chimera PV1(RIPO)

(2013) Nusrat Jahan et al.   PLoS One

Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation

(2013) M. P. Hall et al.   RNA

RAVER1 is a coactivator of MDA5-mediated cellular antiviral response

(2013) He Chen et al.   Journal of Molecular Cell Biology

Defining the roles and interactions of PTB

(2012) Panagiota Kafasla et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

(2012) Niroshika Keppetipola et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A new function of ROD1 in nonsense-mediated mRNA decay

(2012) T.F. Brazão et al.   FEBS LETTERS

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life Cycle

(2012) S. Vashist et al.   JOURNAL OF VIROLOGY

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

(2012) Sika Zheng et al.   NATURE NEUROSCIENCE

Effect of a natural mutation in the 5′ untranslated region on the translational control of p53 mRNA

(2012) D Khan et al.   ONCOGENE

Polypyrimidine Tract Binding Protein (hnRNP I) Is Possibly a Conserved Modulator of miRNA-Mediated Gene Regulation

(2012) Bart Engels et al.   PLoS One

IRES-dependent translation of egr2 is induced under inflammatory conditions

(2012) D. Rubsamen et al.   RNA

The human insulin mRNA is partly translated via a cap- and eIF4A-independent mechanism

(2011) Rikard G. Fred et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RETRACTED: Polypyrimidine tract-binding protein regulates the cell cycle through IRES-dependent translation of CDK11p58 in mouse embryonic stem cells

(2011) Satona Ohno et al.   CELL CYCLE

Decoding muscle alternative splicing

(2011) Miriam Llorian et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Transcriptional regulation of the human Raver2 ribonucleoprotein gene

(2011) Maria Grazia Romanelli et al.   GENE

Regulation of the Mutually Exclusive Exons 8a and 8 in the CaV1.2 Calcium Channel Transcript by Polypyrimidine Tract-binding Protein

(2011) Zhen Zhi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RBM4 down-regulates PTB and antagonizes its activity in muscle cell–specific alternative splicing

(2011) Jung-Chun Lin et al.   JOURNAL OF CELL BIOLOGY

Polypyrimidine Tract-Binding Protein Is Critical for the Turnover and Subcellular Distribution of CD40 Ligand mRNA in CD4+ T Cells

(2011) R. Matus-Nicodemos et al.   JOURNAL OF IMMUNOLOGY

Characterization of MRP RNA–protein interactions within the perinucleolar compartment

(2011) Callie Pollock et al.   MOLECULAR BIOLOGY OF THE CELL

U1 snRNA Directly Interacts with Polypyrimidine Tract-Binding Protein during Splicing Repression

(2011) Shalini Sharma et al.   MOLECULAR CELL

Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing

(2011) Amar Joshi et al.   STRUCTURE

Evolution of SR protein and hnRNP splicing regulatory factors

(2011) Anke Busch et al.   Wiley Interdisciplinary Reviews-RNA

Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs

(2011) Myriam Gorospe et al.   Frontiers in Molecular Neuroscience

Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA

(2010) M. Chen et al.   CANCER RESEARCH

Polypyrimidine tract binding protein regulates IRES-mediated translation of p53 isoforms

(2010) Richa Grover et al.   CELL CYCLE

Polypyrimidine tract-binding protein stimulates the poliovirus IRES by modulating eIF4G binding

(2010) Panagiota Kafasla et al.   EMBO JOURNAL

Polypyrimidine tract-binding protein interacts with coxsackievirus B3 RNA and influences its translation

(2010) B. Verma et al.   JOURNAL OF GENERAL VIROLOGY

Interactions between PTB RRMs Induce Slow Motions and Increase RNA Binding Affinity

(2010) Caroline M. Maynard et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional Analysis of RNA Structures Present at the 3' Extremity of the Murine Norovirus Genome: the Variable Polypyrimidine Tract Plays a Role in Viral Virulence

(2010) D. Bailey et al.   JOURNAL OF VIROLOGY

Breaking the second genetic code

(2010) J. Ramón Tejedor et al.   NATURE

Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

(2010) Miriam Llorian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

hnRNP Q and PTB modulate the circadian oscillation of mouse Rev-erb α via IRES-mediated translation

(2010) Do-Yeon Kim et al.   NUCLEIC ACIDS RESEARCH

Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer

(2010) X He et al.   ONCOGENE

Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1

(2010) L C Cobbold et al.   ONCOGENE

High Glucose Suppresses Human Islet Insulin Biosynthesis by Inducing miR-133a Leading to Decreased Polypyrimidine Tract Binding Protein-Expression

(2010) Rikard G. Fred et al.   PLoS One

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

(2010) C. V. Clower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA looping by PTB: Evidence using FRET and NMR spectroscopy for a role in splicing repression

(2010) R. Lamichhane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-transcriptional regulation in Lymphocytes: The case of CD154

(2010) Stefano Vavassori et al.   RNA Biology

Polypyrimidine tract-binding protein influences negative strand RNA synthesis of dengue virus

(2009) Linbin Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Domains of Polypyrimidine Tract Binding Protein Have Distinct RNA Structural Preferences†

(2009) Caroline Clerte et al.   BIOCHEMISTRY

Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines

(2009) Hannah C. Cheung et al.   BRAIN

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Polypyrimidine tract binding proteins (PTB) regulate the expression of apoptotic genes and susceptibility to caspase-dependent apoptosis in differentiating cardiomyocytes

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

A conserved peptide motif in Raver2 mediates its interaction with the polypyrimidine tract-binding protein

(2009) Berenike Henneberg et al.   EXPERIMENTAL CELL RESEARCH

Polypyrimidine tract-binding protein is essential for early mouse development and embryonic stem cell proliferation

(2009) Masaki Shibayama et al.   FEBS Journal

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation

(2009) F. Besse et al.   GENES & DEVELOPMENT

Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome

(2009) Yang Bian et al.   HUMAN MOLECULAR GENETICS

A Region within the 5′-Untranslated Region of Hypoxia-inducible Factor-1α mRNA Mediates Its Turnover in Lung Adenocarcinoma Cells

(2009) Ming Jen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Polypyrimidine Tract-binding Protein Is Required for Efficient Dengue Virus Propagation and Associates with the Viral Replication Machinery

(2009) Azlinda Anwar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polypyrimidine tract-binding protein is relocated to the cytoplasm and is required during dengue virus infection in Vero cells

(2009) R. A. Agis-Juarez et al.   JOURNAL OF GENERAL VIROLOGY

A Role for Polypyrimidine Tract Binding Protein in the Establishment of Focal Adhesions

(2009) I. Babic et al.   MOLECULAR AND CELLULAR BIOLOGY

The hnRNA-Binding Proteins hnRNP L and PTB Are Required for Efficient Translation of the Cat-1 Arginine/Lysine Transporter mRNA during Amino Acid Starvation

(2009) M. Majumder et al.   MOLECULAR AND CELLULAR BIOLOGY

RNA Processing: Redrawing the Map of Charted Territory

(2009) Anna Corrionero et al.   MOLECULAR CELL

Polypyrimidine Tract Binding Protein Stabilizes the Encephalomyocarditis Virus IRES Structure via Binding Multiple Sites in a Unique Orientation

(2009) Panagiota Kafasla et al.   MOLECULAR CELL

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

(2009) Yuanchao Xue et al.   MOLECULAR CELL

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins

(2009) Debashish Ray et al.   NATURE BIOTECHNOLOGY

RNA processing and its regulation: global insights into biological networks

(2009) Donny D. Licatalosi et al.   NATURE REVIEWS GENETICS

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

(2009) Mo Chen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The human insulin receptor mRNA contains a functional internal ribosome entry segment

(2009) Keith A. Spriggs et al.   NUCLEIC ACIDS RESEARCH

A physical and functional link between splicing factors promotes pre-mRNA 3′ end processing

(2009) Stefania Millevoi et al.   NUCLEIC ACIDS RESEARCH

Role of Polypyrimidine Tract Binding Protein in Mediating Internal Initiation of Translation of Interferon Regulatory Factor 2 RNA

(2009) Debojyoti Dhar et al.   PLoS One

Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence

(2009) D. C. Reid et al.   RNA

Raver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal Adhesions

(2009) Jun Hyuck Lee et al.   STRUCTURE

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

RNA recognition motifs: boring? Not quite

(2008) Antoine Cléry et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS

Polypyrimidine Tract-binding Protein (PTB) Differentially Affects Malignancy in a Cell Line-dependent Manner

(2008) Chen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insights into internal ribosome entry site elements relevant for viral gene expression

(2008) E. Martinez-Salas et al.   JOURNAL OF GENERAL VIROLOGY

The importance of RNA binding proteins in preproinsulin mRNA stability

(2008) R FRED et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Mouse period 2 mRNA circadian oscillation is modulated by PTB–mediated rhythmic mRNA degradation

(2008) Kyung-Chul Woo et al.   NUCLEIC ACIDS RESEARCH

Visualizing protein-RNA interactions inside cells by fluorescence resonance energy transfer

(2008) M. Lorenz   RNA

Splicing regulation: From a parts list of regulatory elements to an integrated splicing code

(2008) Z. Wang et al.   RNA

MADS: A new and improved method for analysis of differential alternative splicing by exon-tiling microarrays

(2008) Y. Xing et al.   RNA

The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity

(2007) Ines Lahmann et al.   EXPERIMENTAL CELL RESEARCH