Loss of Vps54 Function Leads to Vesicle Traffic Impairment, Protein Mis-Sorting and Embryonic Lethality

The wobbler mouse, an ALS animal model

(2013) Jakob Maximilian Moser et al.   MOLECULAR GENETICS AND GENOMICS

Molecular Identification of tw5: Vps52 Promotes Pluripotential Cell Differentiation through Cell–Cell Interactions

(2012) Michihiko Sugimoto et al.   Cell Reports

Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: Implications for human motor neuron disease

(2011) Ralf Palmisano et al.   BMC NEUROSCIENCE

Reduced GABAergic Inhibition Explains Cortical Hyperexcitability in the Wobbler Mouse Model of ALS

(2010) Jose Luis Nieto-Gonzalez et al.   CEREBRAL CORTEX

Tumor Necrosis Factor-  (TNF- ) Regulates Shedding of TNF-  Receptor 1 by the Metalloprotease-Disintegrin ADAM8: Evidence for a Protease-Regulated Feedback Loop in Neuroprotection

(2010) J. W. Bartsch et al.   JOURNAL OF NEUROSCIENCE

Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex

(2010) F. J. Perez-Victoria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transport according to GARP: receiving retrograde cargo at the trans-Golgi network

(2010) Juan S. Bonifacino et al.   TRENDS IN CELL BIOLOGY

Occurrence of an anomalous endocytic compartment in fibroblasts from Sandhoff disease patients

(2009) Brunella Tancini et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Dual Roles of the Mammalian GARP Complex in Tethering and SNARE Complex Assembly at the trans-Golgi Network

(2009) F. J. Perez-Victoria et al.   MOLECULAR AND CELLULAR BIOLOGY

Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS

(2008) Miriam H. Meisler et al.   Amyotrophic Lateral Sclerosis

Requirement of the Human GARP Complex for Mannose 6-phosphate-receptor-dependent Sorting of Cathepsin D to Lysosomes

(2008) F. Javier Pérez-Victoria et al.   MOLECULAR BIOLOGY OF THE CELL