Article
Agronomy
Deng Pan, Menghao Xia, Qiujuan Luo, Chuanzhen Li, Guorui Yuan, Jinjun Wang, Wei Dou
Summary: The study systematically investigated the sublethal and transgenerational effects of pyridaben exposure on two strains of Panonychus citri mites. The results showed that pyridaben exposure reduced the fecundity of both strains in the parental generation, but increased it in the offspring generation. The population size decreased in the offspring generation of the susceptible strain, while it increased in the resistant strain. These findings suggest that low concentrations of pyridaben exposure can have transgenerational hormesis effects on mite population dynamics.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agronomy
Deng Pan, Meng-Hao Xia, Qiu-Juan Luo, Xun-Yan Liu, Chuan-Zhen Li, Guo-Rui Yuan, Jin-Jun Wang, Wei Dou
Summary: The resistance levels to pyridaben varied greatly among different populations of Panonychus citri in China, with regional differences observed. The development of resistance is associated with substantial fitness costs. This study provides potential implications for developing resistance management strategies for P. citri.
PEST MANAGEMENT SCIENCE
(2023)
Article
Entomology
Xue Dong Chen, Andres Felipe Sandoval-Mojica, Sylvia Imelda Bonilla, Timothy Aaron Ebert, Hunter Gossett, Kirsten S. Pelz-Stelinski, Lukasz L. Stelinski
Summary: The Asian citrus psyllid has the ability to develop high levels of resistance to fenpropathrin through persistent selection. Metabolic detoxification through cytochrome P450 and glutathione S-transferase may play a role in this resistance. Implementing rotation programs with other insecticide classes can manage resistance effectively.
INTERNATIONAL JOURNAL OF PEST MANAGEMENT
(2023)
Article
Environmental Sciences
Ahmed A. A. Aioub, Ahmed S. S. Hashem, Ahmed H. H. El-Sappah, Amged El-Harairy, Amira A. A. Abdel-Hady, Laila A. A. Al-Shuraym, Samy Sayed, Qiulan Huang, Sarah I. Z. Abdel-Wahab
Summary: This study identified and characterized GST genes in the fall armyworm S. frugiperda and evaluated the toxicity of emamectin benzoate (EBZ) and chlorantraniliprole (CHP) on the larvae. A total of 31 GST genes were identified, and SfGSTe10 and SfGSTe13 showed the highest expression after EBZ and CHP treatments. Molecular docking analysis revealed high binding affinity between EBZ and CHP with SfGSTe10 and SfGSTe13. These findings provide important insights into the detoxification processes of S. frugiperda regarding EBZ and CHP.
Article
Agronomy
Ismail Doker, Cengiz Kazak, Recep Ay
Summary: Monitoring of acaricide resistance in phytophagous mites is crucial for effective pest management. A study conducted in citrus orchards in Cukurova region of Turkey found that certain populations of citrus red mites have developed resistance to commonly used acaricides. It is suggested that rotating acaricides with different modes of action is fundamental to prevent potential resistance problems.
Article
Biochemistry & Molecular Biology
Warin Rangubpit, Eukote Suwan, Danai Sangthong, Kannika Wongpanit, Roger W. Stich, Prapasiri Pongprayoon, Sathaporn Jittapalapong
Summary: In this study, molecular dynamics simulations were conducted to investigate the binding of GTX and GSH to RmGST. It was found that GSH binds tighter and sits rigidly inside the G-site, while GTX occupies both active sites.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Xingang Li, Yuanting Pang, Yiwang Zhong, Zhandong Cai, Qibin Ma, Ke Wen, Hai Nian
Summary: In this study, a tau-like glutathione transferase family gene named GmGSTU23 was identified in soybean, which showed a concentration-time-specific expression pattern in response to salt stress. Transgenic lines with GmGSTU23 displayed enhanced salt tolerance, root length, and fresh weight compared to the wild type. Changes in glutathione pools and associated enzyme activity were observed, indicating that GmGSTU23 enhances the activity of glutathione transferase to scavenge reactive oxygen species and glutathione, thereby conferring enhanced tolerance to salt stress in plants.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Chang Lu, Pengyan Zhang, Shuang Li, Mengzhen Cheng, Delin Duan
Summary: In this study, 32 SjGST genes were identified in Saccharina japonica and categorized into three groups. Functional analysis showed that SjGSTs enhance stress resistance in the seaweed, particularly under low salinity, drought, and high temperature conditions. Biochemical parameter analysis confirmed the enzyme activity and optimal conditions of SjGSTs.
Article
Plant Sciences
Linlin Wang, Hongbo Fu, Juan Zhao, Jiagang Wang, Shuqi Dong, Xiangyang Yuan, Xiaorui Li, Mingxun Chen
Summary: This study conducted genome-wide identification and expression characteristics analysis of the GST gene family in foxtail millet. The results showed the presence of 73 GST genes (SiGSTs) divided into seven classes in the foxtail millet genome. The study provides a theoretical basis for identifying foxtail millet GST family information and improving their responses to different stresses.
Article
Agronomy
Yushi Jiang, Yuzhe Zhang, Ruijie Duan, Jiayi Fan, Peng Jiao, Hongji Sun, Shuyan Guan, Siyan Liu
Summary: ZmGST26 was found to be downregulated in maize under drought stress. Overexpression of ZmGST26 in Arabidopsis resulted in increased sensitivity to drought stress and ABA, as well as inhibited ABA-mediated stomatal closure. ZmGST26 overexpression decreased the resistance of Arabidopsis to drought stress and led to the accumulation of reactive oxygen species.
Article
Neurosciences
Bo Cheng, Xiaoliang Hong, Linfang Wang, Yuanyuan Cao, Dengli Qin, Han Zhou, Dianshuai Gao
Summary: Curzerene inhibits the progression of glioma by suppressing the expression of GSTA4 and matrix metalloproteinase 9, and inhibiting the activation of the mTOR pathway. It also induces apoptosis and reduces invasion and migration of glioma cells. In vivo studies have shown that Curzerene significantly inhibits tumor growth and prolongs survival time.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Editorial Material
Biochemistry & Molecular Biology
Tiffany M. Russell, Des R. Richardson
Summary: GSTs are versatile proteins that play important roles in detoxification and cellular nitric oxide metabolism. They have the ability to convert organic nitrates into nitric oxide, thereby regulating vasodilation. GSTs are also considered suitable targets for pharmaceutical development, particularly in the field of anti-cancer drugs.
Article
Entomology
Qin-Zhe Sun, Wan-Jun Yang, Yu-Fei Shi, Wen-Jie Chai, Ruo-Yu Chen, Yan-Kui Jiang, Yan-Chun Zhang, Zi-Guo Wang, Zhao-Jun Wang, Jin-Zhi Niu, Jin-Jun Wang
Summary: RNAi has the potential to control spider mite pests without harming natural predators. This study identified and investigated HGT genes as potential RNAi targets for spider mite control. The results showed that these genes can be used as natural and specific RNAi targets without adverse effects on predatory mites.
ENTOMOLOGIA GENERALIS
(2023)
Article
Microbiology
Alvaro de Obeso Fernandez del Valle, Christian Quintus Scheckhuber, David Armando Chavaro-Perez, Erandi Ortega-Barragan, Sutherland K. Maciver
Summary: Some members of Acanthamoeba are facultative pathogens that can infect the cornea, causing Acanthamoeba keratitis. During encystation, there is an upregulation of glutathione S-transferase (GST) genes, which play a role in maintaining redox balance. Inhibiting GST with ethacrynic acid decreases cell viability by 70%. Targeting GST and associated processes could be a potential treatment strategy to reduce relapses of Acanthamoeba infection.
Article
Entomology
Lu-Yan Cheng, Dong-Yuan Hou, Qin-Zhe Sun, Shi-Jiang Yu, Si-Chen Li, Hao-Qiang Liu, Lin Cong, Chun Ran
Summary: This study identified a spirodiclofen-resistant strain of citrus red mite with significantly increased expression of the CYP385C10 gene, potentially contributing to resistance. Functional analysis through RNAi further confirmed that overexpression of the P450 gene CYP385C10 may be involved in spirodiclofen resistance in P. citri.