Pro-Inflammatory S100A8 and S100A9 Proteins: Self-Assembly into Multifunctional Native and Amyloid Complexes

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes

(2011) H. Wittkowski et al.   ANNALS OF THE RHEUMATIC DISEASES

S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll-like receptor 4: Implications for bone destruction in murine antigen-induced arthritis

(2011) Lilyanne C. Grevers et al.   ARTHRITIS AND RHEUMATISM

Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis

(2011) Peter L. E. M. van Lent et al.   ARTHRITIS AND RHEUMATISM

Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4

(2011) Rik F. P. Schelbergen et al.   ARTHRITIS AND RHEUMATISM

Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus

(2011) Thomas E. Kehl-Fie et al.   Cell Host & Microbe

Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent

(2011) Matteo Bianchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression

(2011) M. Ichikawa et al.   MOLECULAR CANCER RESEARCH

The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping

(2010) Thorsten Ostendorp et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Natural and amyloid self-assembly of S100 proteins: structural basis of functional diversity

(2010) Günter Fritz et al.   FEBS Journal

Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity

(2010) Massimo Stefani   FEBS Journal

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells

(2010) Karin Loser et al.   NATURE MEDICINE

S100A8 and S100A9 in experimental osteoarthritis

(2010) Hala Zreiqat et al.   ARTHRITIS RESEARCH & THERAPY

Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis

(2009) Marieke A. D. van Zoelen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function

(2009) Olga V Moroz et al.   BMC BIOCHEMISTRY

Metal ions modulate the folding and stability of the tumor suppressor protein S100A2

(2009) Hugo M. Botelho et al.   FEBS Journal

The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

(2009) Jan M. Ehrchen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Amyloid Formation by the Pro-Inflammatory S100A8/A9 Proteins in the Ageing Prostate

(2009) Kiran Yanamandra et al.   PLoS One

Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

(2009) Per Björk et al.   PLOS BIOLOGY

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis

(2008) P. L. E. M. van Lent et al.   ARTHRITIS AND RHEUMATISM

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

(2008) Olga Turovskaya et al.   CARCINOGENESIS

S100A8 and S100A9 Mediate Endotoxin-Induced Cardiomyocyte Dysfunction via the Receptor for Advanced Glycation End Products

(2008) John H. Boyd et al.   CIRCULATION RESEARCH

Mast Cell and Monocyte Recruitment by S100A12 and Its Hinge Domain

(2008) Wei Xing Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

(2008) S. Ghavami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Global Gene Expression Profiling Unveils S100A8/A9 as Candidate Markers in H-Ras-Mediated Human Breast Epithelial Cell Invasion

(2008) A. Moon et al.   MOLECULAR CANCER RESEARCH

Cancer and complement

(2008) Suzanne Ostrand-Rosenberg   NATURE BIOTECHNOLOGY

Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Theraphy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial

(2007) David A. Morrow et al.   AMERICAN HEART JOURNAL

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis

(2007) P L E M van Lent et al.   ANNALS OF THE RHEUMATIC DISEASES

A review of the S100 proteins in cancer

(2007) I. Salama et al.   EJSO