Role of Versican, Hyaluronan and CD44 in Ovarian Cancer Metastasis

Tumor-Endothelial Interaction Links the CD44+/CD24- Phenotype with Poor Prognosis in Early-Stage Breast Cancer

(2015) Martin Buess et al.   NEOPLASIA

Peritoneal Adhesion and Angiogenesis in Ovarian Carcinoma Are Inversely Regulated by Hyaluronan: The Role of Gonadotropins

(2015) Yael Chagit Tzuman et al.   NEOPLASIA

CD44, a therapeutic target for metastasising tumours

(2010) Véronique Orian-Rousseau   EUROPEAN JOURNAL OF CANCER

Up-regulation of stromal versican expression in advanced stage serous ovarian cancer

(2010) Sue Ghosh et al.   GYNECOLOGIC ONCOLOGY

Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

(2010) C. B. Thompson et al.   MOLECULAR CANCER THERAPEUTICS

Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

(2010) Sonia Guedan et al.   MOLECULAR THERAPY

A novel intralymphatic nanocarrier delivery system for cisplatin therapy in breast cancer with improved tumor efficacy and lower systemic toxicity in vivo

(2009) Mark S. Cohen et al.   AMERICAN JOURNAL OF SURGERY

Reversal effects of hyaluronan oligosaccharides on adriamycin resistance of K562/A02 cells

(2009) Xiangzhen Cui et al.   ANTI-CANCER DRUGS

Expression of Hyaluronan Synthases (HAS1–3) and Hyaluronidases (HYAL1–2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content

(2009) Timo K Nykopp et al.   BMC CANCER

CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts

(2009) E Marangoni et al.   BRITISH JOURNAL OF CANCER

Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression

(2009) H Chen et al.   BRITISH JOURNAL OF CANCER

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The biological role and regulation of versican levels in cancer

(2009) Carmela Ricciardelli et al.   CANCER AND METASTASIS REVIEWS

Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response

(2009) Laura Alaniz et al.   CANCER LETTERS

Abrogating Drug Resistance in Malignant Peripheral Nerve Sheath Tumors by Disrupting Hyaluronan-CD44 Interactions with Small Hyaluronan Oligosaccharides

(2009) M. G. Slomiany et al.   CANCER RESEARCH

Inhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides

(2009) M. G. Slomiany et al.   CLINICAL CANCER RESEARCH

Positive hyaluronan/PEI/DNA complexes as a target-specific intracellular delivery to malignant breast cancer

(2009) Xiyang Sun et al.   DRUG DELIVERY

Role of CD44s and CD44v6 on human breast cancer cell adhesion, migration, and invasion

(2009) Alaa Afify et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells

(2009) Sung Pil Hong et al.   INTERNATIONAL JOURNAL OF CANCER

Modulation of hyaluronan production by CD44 positive glioma cells

(2009) Marzenna Wiranowska et al.   INTERNATIONAL JOURNAL OF CANCER

Versican overexpression in human breast cancer lesions: Known and new isoforms for stromal tumor targeting

(2009) Philippe Kischel et al.   INTERNATIONAL JOURNAL OF CANCER

Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

(2009) M. Kaur et al.   MOLECULAR CANCER THERAPEUTICS

Target Specific Intracellular Delivery of siRNA/PEI−HA Complex by Receptor Mediated Endocytosis

(2009) Ge Jiang et al.   MOLECULAR PHARMACEUTICS

Prognostic Significance of CD44s Expression in Biliary Tract Cancers

(2008) Sang Min Lee et al.   ANNALS OF SURGICAL ONCOLOGY

Hyaluronic Acid−Paclitaxel Conjugate Micelles: Synthesis, Characterization, and Antitumor Activity

(2008) Hyukjin Lee et al.   BIOCONJUGATE CHEMISTRY

Induction of apoptosis by anti-CD44 antibody in human chondrosarcoma cell line SW1353

(2008) Makoto YOSHIDA et al.   BIOMEDICAL RESEARCH-TOKYO

Inhibition of CD44 expression in hepatocellular carcinoma cells enhances apoptosis, chemosensitivity, and reduces tumorigenesis and invasion

(2008) Zhigang Xie et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A Paclitaxel-Hyaluronan Bioconjugate Targeting Ovarian Cancer Affords a Potent In vivo Therapeutic Activity

(2008) A. Banzato et al.   CLINICAL CANCER RESEARCH

Hyaluronan Binding to Link Module of TSG-6 and to G1 Domain of Aggrecan Is Differently Regulated by pH

(2008) Boon Chin Heng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD44-Epidermal Growth Factor Receptor Interaction Mediates Hyaluronic Acid-promoted Cell Motility by Activating Protein Kinase C Signaling Involving Akt, Rac1, Phox, Reactive Oxygen Species, Focal Adhesion Kinase, and MMP-2

(2008) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin

(2008) Hilary A. Kenny et al.   JOURNAL OF CLINICAL INVESTIGATION

An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor

(2008) Sumio Chono et al.   JOURNAL OF CONTROLLED RELEASE

Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model

(2008) K. Almholt et al.   MOLECULAR CANCER THERAPEUTICS

DNA vaccination with CD44 variant isoform reduces mammary tumor local growth and lung metastasis

(2008) Shulamit Batya Wallach-Dayan et al.   MOLECULAR CANCER THERAPEUTICS

Vitronectin and Its Receptors Partly Mediate Adhesion of Ovarian Cancer Cells to Peritoneal Mesothelium in vitro

(2008) Loraine Heyman et al.   TUMOR BIOLOGY