Article
Chemistry, Applied
Ahmed A. Fadda, Eman El-Gendy, Hala M. Refat, Eman H. Tawfik
Summary: In this study, a series of new porphyrin derivatives were successfully synthesized and showed promising activity as antimicrobial and antioxidant agents. The compounds 4c, 4e, 4g, 5c, and 5d exhibited the highest antimicrobial activity, while compounds 4a, 4f, 5a, 5b, and 5d showed the highest antioxidant activity.
Review
Nutrition & Dietetics
Hugo J. Bello, Alberto Caballero-Garcia, Daniel Perez-Valdecantos, Enrique Roche, David C. Noriega, Alfredo Cordova-Martinez
Summary: A systematic review was conducted to investigate the role of vitamin D in muscle recovery post-exercise, with inconclusive results suggesting a potential anti-inflammatory effect. Further research is needed to confirm these findings.
Review
Food Science & Technology
Andressa Roehrig Volpe-Fix, Elias de Franca, Jean Carlos Silvestre, Ronaldo Vagner Thomatieli-Santos
Summary: Food bioactive compounds (FBC) are substances found in fruits, vegetables, and other sources that have physiological effects on individuals who consume them. Some FBCs, such as polyphenols, have antioxidant and anti-inflammatory properties. This review explores the effects of supplementing with various polyphenols on oxidative stress and post-exercise inflammation markers. The findings suggest that cocoa, green tea extract, and curcumin can help alleviate cell damage and inflammation caused by exercise, but conflicting results are found for anthocyanins, quercetins, and resveratrol. The impact of simultaneously supplementing multiple FBCs is also discussed.
Article
Physiology
Cesar Augustus Zocoler de Sousa, Ana Paula Renno Sierra, Bryan Steve Martinez Galan, Jaqueline Fernanda de Sousa Maciel, Richelieau Manoel, Hermes Vieira Barbeiro, Heraldo Possolo de Souza, Maria Fernanda Cury-Boaventura
Summary: Endurance exercise increases the expression of exercise-induced peptides that aid in muscle repair and regeneration. A study on marathon runners showed an increase in various exercise-induced cytokines immediately after the race, including IL-6, IL-8, TNF-alpha, IL-10, decorin, GDF-15, BDNF, follistatin, and FGF-21. The decrease in myostatin, IL-15, musclin, and apelin levels post-race suggested muscle regeneration.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Endocrinology & Metabolism
Tom S. O. Jameson, George F. Pavis, Marlou L. Dirks, Benjamin P. Lee, Doaa R. Abdelrahman, Andrew J. Murton, Craig Porter, Nima Alamdari, Catherine R. Mikus, Benjamin T. Wall, Francis B. Stephens
Summary: The study found that ingesting protein-polyphenol drinks can accelerate the recovery of muscle function by attenuating inflammatory NF-.B transcriptional signaling, rather than increasing myofibrillar protein synthesis rates.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Physiology
Yucong Wang, Tao Xu, Hui Zhao, Chunxiao Gu, Zhongzheng Li
Summary: This study found that taurine intake can reduce the inflammatory response caused by exercise, as evidenced by decreased levels of IL-6 and AST, which in turn may improve running performance.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Jia Zhang, Yuqi Zhou, Zhaoting Jiang, Chenhui He, Bo Wang, Qi Wang, Zeqian Wang, Tong Wu, Xiaoqi Chen, Ziwei Deng, Chunying Li, Zhe Jian
Summary: In this study, novel sunscreen products based on melanin-inspired PDA nanoparticles were designed and prepared, showing superior effects in protecting against photodamage and photoaging. The mechanism of action of the sunscreen was also investigated, providing new insights for the development of sun protection products.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Nutrition & Dietetics
Katsuhiko Suzuki
Summary: This article discusses how nutrition may help in recovery from the harmful effects of strenuous exercise and training, focusing on nutritional supplements. The effects of various supplements on immune function and how 3-hydroxy-3-methyl butyrate monohydrate (HMB) may offset muscle damage are reviewed. Additional verification of the safety and efficacy of these supplements is still necessary, but they show potential applications for health promotion and disease prevention among athletes and more diverse populations.
Article
Nutrition & Dietetics
S. C. Broome, R. D. Atiola, A. J. Braakhuis, C. J. Mitchell, T. L. Merry
Summary: This study examined the effect of mitochondria-targeted antioxidant supplementation on muscle recovery following exercise. The results showed that MitoQ did not alleviate muscle soreness and may delay the recovery of muscle function after eccentric exercise.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Nutrition & Dietetics
Myunghee Kim, Hyeyoon Eo, Josephine Gahyun Lim, Hyunjung Lim, Yunsook Lim
Summary: This meta-analysis found that dietary vitamin E supplementation can attenuate exercise-induced muscle damage, especially when the supplementation is less than 500 IU.
Article
Agriculture, Dairy & Animal Science
Yueping Chen, Pingping Zha, Hongrui Xu, Yanmin Zhou
Summary: This study investigated the protective effects of chlorogenic acid (CGA) on broilers with DSS-induced intestinal damage. The results showed that CGA could partially prevent the increased intestinal permeability, oxidative damage, and inflammation caused by DSS.
Article
Nutrition & Dietetics
Matthew Stefan, Matthew Sharp, Raad Gheith, Ryan Lowery, Charlie Ottinger, Jacob Wilson, Shane Durkee, Aouatef Bellamine
Summary: The study indicates that L-carnitine tartrate supplementation can improve short-term recovery among athletes, while longer-term effects in the general population need further research. The experiment found that L-carnitine tartrate supplementation for 5 weeks could enhance perceived recovery and reduce soreness, as well as lower serum creatine kinase levels.
Review
Hematology
Jordan D. D. Dimitrov, Lubka T. T. Roumenina, Gina Perrella, Julie Rayes
Summary: Regardless of the cause, hemolytic diseases are associated with thrombosis, inflammation, and immune dysregulation, resulting in organ damage and poor outcomes. Hemolysis not only leads to anemia and loss of the anti-inflammatory functions of red blood cells, but also releases damage-associated molecular patterns, such as ADP, hemoglobin, and heme, which trigger a hyperinflammatory and hypercoagulable state through various receptors and signaling pathways. Extracellular free heme, in particular, can activate platelets, endothelial cells, innate cells, as well as the coagulation and complement cascades, thereby promoting thrombo-inflammatory events. This review discusses the main mechanisms by which hemolysis, especially heme, drives this thrombo-inflammatory environment and explores the impact of hemolysis on the host response to secondary infections.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Clinical Neurology
Tao Wang, Haibo Chen, Shuyun Xia, Xiaofang Chen, Hu Sun, Zhixin Xu
Summary: The study found that pre-treatment with Par C can improve nerve function, suppress oxidative stress and pro-inflammatory factors release, increase antioxidant expression, and decrease pro-inflammatory cytokines expression in rats with cerebral ischemia damage.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Article
Food Science & Technology
Chaoya Zhao, Yurong Gong, Lin Zheng, Mouming Zhao
Summary: This study investigated the effects of whey protein concentrate (WPC) and whey protein hydrolysate (WPH) on energy metabolism, muscle injury, and underlying mechanisms in exercise mice. The results showed that WPH had better influences than WPC in delaying glycogens consumption and promoting lactate and urea nitrogen elimination. Additionally, WPC and WPH attenuated muscle damage via inhibiting inflammatory response.
Correction
Geriatrics & Gerontology
J. Dyer, G. Davison, S. M. Marcora, Alexis R. Mauger
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Physiology
Alexander T. Carswell, Kevin Howland, Borja Martinez-Gonzalez, Pauline Baron, Glen Davison
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2020)
Article
Sport Sciences
Glen Davison, Eleanor Perkins, Arwel W. Jones, Gabriella M. Swart, Alex R. Jenkins, Hayley Robinson, Kimberly Dargan
Summary: This study investigated the effects of ColdZyme Mouth Spray on self-reported upper respiratory tract infection in competitive endurance athletes. The results showed that ColdZyme significantly reduced the duration of infections, particularly with good compliance with instructions for use.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2021)
Review
Sport Sciences
Sarah Chantler, Alex Griffiths, Jamie Matu, Glen Davison, Ben Jones, Kevin Deighton
Summary: An acute bout of exercise can lead to increased gut damage and permeability in healthy populations, with greater damage observed in hot conditions. Exercise duration does not significantly affect gut damage or permeability outcomes. Further research into nutritional strategies to minimize gut damage post-exercise is needed.
Review
Nutrition & Dietetics
Glen Davison
Summary: Bovine colostrum has shown potential benefits for gut permeability and damage markers, immune function, and illness risk in sports nutrition. However, there is limited evidence for effects on body composition and physical performance, requiring further research to fully understand the mechanisms.
Article
Sport Sciences
Henry B. Ogden, Joanne L. Fallowfield, Robert B. Child, Glen Davison, Simon C. Fleming, Simon K. Delves, Alison Millyard, Caroline S. Westwood, Joseph D. Layden
Summary: The study found that acute low-dose glutamine (GLN) supplementation may worsen intestinal permeability before high-intensity exertional-heat stress, but does not influence small intestinal epithelial injury or microbial translocation.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2022)
Article
Physiology
Hannah F. Sangan, James G. Hopker, Glen Davison, Shaun J. McLaren
Summary: The study assessed the reliability and construct validity of a self-paced, submaximal run test (SRTRPE) for monitoring aerobic fitness. Results showed large correlations between SRTRPE parameters and VO2max, with the highest reliability observed at intensity RPE 17.
INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Eleanor Perkins, Glen Davison
Summary: The study investigated the relationship between salivary EBV DNA and URS in professional football players, finding that salivary IgA is a useful marker for URS risk but EBV DNA is not. Further research is needed to fully determine the utility of these markers in predicting URS episodes.
RESEARCH QUARTERLY FOR EXERCISE AND SPORT
(2022)
Meeting Abstract
Oncology
C. Harper-Wynne, J. L. Glendenning, G. Davison
ANNALS OF ONCOLOGY
(2022)
Review
Multidisciplinary Sciences
Sarah Chantler, Alex Griffiths, Jamie Matu, Glen Davison, Adrian Holliday, Ben Jones
Summary: Nutrition strategies and supplements may play a role in reducing exercise-induced gastrointestinal cell damage and permeability. Studies have shown that bovine colostrum, glutamine, carbohydrate supplementation, and maintaining hydration levels can help reduce endothelial damage and improve gut permeability associated with exercise. Some positive findings have also been observed with single strain probiotics.
Article
Microbiology
Matthew J. W. Furber, Gregory R. Young, Giles S. Holt, Simone Pyle, Glen Davison, Michael G. Roberts, Justin D. Roberts, Glyn Howatson, Darren L. Smith
Summary: This study investigated the impact of high-protein or high-carbohydrate diets on endurance performance and gut microbial communities. It found that high-carbohydrate diets improved performance, while high-protein diets reduced performance. The gut phageome, specifically bacteriophage communities, were most affected by dietary manipulation. Stable gut microbial communities were associated with better athletic performance.
Article
Physiology
Sarah Chantler, Alex Griffiths, Padraic Phibbs, Gregory Roe, Carlos Ramirez-Lopez, Glen Davison, Ben Jones, Kevin Deighton
Summary: The study aimed to assess the impact of rugby training on intestinal endothelial cell damage and permeability in academy rugby players. The results showed that rugby training led to increased intestinal endothelial cell damage and permeability, and this effect persisted after six weeks of preseason training.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Editorial Material
Environmental Sciences
Glen Davison
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Editorial Material
Nutrition & Dietetics
David C. Nieman, Glen Davison, Vassilis Mougios, Laurel M. Wentz
FRONTIERS IN NUTRITION
(2023)
Article
Clinical Neurology
Anna Ferrusola-Pastrana, Glen Davison, Stephen N. Meadows
Summary: A weekly community-based multimodal exercise program can improve and maintain physical and cognitive function in individuals with Parkinson's Disease. The program showed significant improvements in walking capacity, functional mobility, lower extremity strength, grip strength, cognition, and BDNF levels.
PARKINSONISM & RELATED DISORDERS
(2023)