Article
Multidisciplinary Sciences
Jonathan Edlund, Kostas Haris, Ellen Ostenfeld, Marcus Carlsson, Einar Heiberg, Sebastian Johansson, Bjorn Ostenson, Ning Jin, Anthony H. Aletras, Katarina Steding-Ehrenborg
Summary: This study developed a semi-automatic algorithm to sort real-time cardiovascular magnetic resonance (CMR) images according to breathing, facilitating quantification of left ventricular (LV) function during free breathing exercise. The algorithm was validated for exercise by comparing LV mass during exercise to rest.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Karol Curila, Pavel Jurak, Marek Jastrzebski, Frits Prinzen, Petr Waldauf, Josef Halamek, Kevin Vernooy, Radovan Smisek, Jakub Karch, Filip Plesinger, Pawel Moskal, Marketa Susankova, Lucie Znojilova, Luuk Heckman, Ivo Viscor, Vlastimil Vondra, Pavel Leinveber, Pavel Osmancik
Summary: The study compared the effects of different physiological pacing techniques on ventricular depolarization, showing that nonselective left bundle branch pacing resulted in greater interventricular electrical dyssynchrony, while left ventricular septal myocardial pacing caused prolonged lateral wall depolarization.
Article
Multidisciplinary Sciences
Tsung-Yu Ko, Hsien-Li Kao, Ying-Ju Liu, Chih-Fan Yeh, Ching-Chang Huang, Ying-Hsien Chen, Chi-Sheng Hung, Chih-Yang Chan, Lung-Chun Lin, Yih-Sharng Chen, Mao-Shin Lin
Summary: The study aimed to compare LV mass regression and remodeling in TAVR patients with and without conduction disturbances (CD). Significant improvement in LV function and reduction in LV volume were observed in non-CD patients at 1 year, while sustained LV mass regression within 3 years was only found in patients without CD.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Zhixin Jiang, Tian Wu, Yixian Wu, Zenghong Chen, Wen Yang, Chongchong Chen, Xiujuan Zhou, Qijun Shan
Summary: The present study compared the effects of left bundle branch area pacing (LBBAP) on cardiac function and clinical outcomes in patients with left bundle branch block (LBBB) and left ventricular ejection fraction (LVEF) > 35% vs. <= 35%. The results showed that LBBAP can significantly shorten QRS duration and improve cardiac function in both groups.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Karol Curila, Pavel Jurak, Kevin Vernooy, Marek Jastrzebski, Petr Waldauf, Frits Prinzen, Josef Halamek, Marketa Susankova, Lucie Znojilova, Radovan Smisek, Jakub Karch, Filip Plesinger, Pawel Moskal, Luuk Heckman, Jan Mizner, Ivo Viscor, Vlastimil Vondra, Pavel Leinveber, Pavel Osmancik
Summary: This study aimed to compare differences in ventricular depolarization during different ventricular capture types in left bundle branch pacing (LBBp), and found that myocardial left septal pacing (LVSP) resulted in better interventricular synchrony than non-selective LBB pacing (nsLBBp) and selective LBB pacing (sLBBp). LVSP also did not significantly prolong depolarization of the left ventricular lateral wall, making it a promising option for bradycardia patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Yankai Mao, Jurgen Duchenne, Yuan Yang, Christophe Garweg, Ying Yang, Xia Sheng, Jiefang Zhang, Yang Ye, Min Wang, Maria F. Paton, Alexis Puvrez, Gabor Voros, Mingming Ma, Guosheng Fu, Jens-Uwe Voigt
Summary: Left bundle branch pacing (LBBP) was found to better preserve left ventricular (LV) mechanical synchronicity compared to right ventricular pacing (RVP), resulting in smaller mechanical dyssynchrony, less abnormal myocardial motion patterns, and better preserved LV function.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Rujie Zheng, Shengjie Wu, Songjie Wang, Lan Su, Kenneth A. Ellenbogen, Weijian Huang
Summary: A case of interventricular septal hematoma complicating LBBP lead implantation was reported. The hematoma was identified and resolved with urgent coronary angiography and echocardiography, respectively. Pacing parameters and cardiac function remained stable during the 6-month follow-up.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Hyue Mee Kim, In-Chang Hwang, Yeonyee Elizabeth Yoon, Jun-Bean Park, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim, Yaeji Lim, Goo-Yeong Cho
Summary: This study found that 2D global longitudinal strain (GLS) is associated with cardiovascular outcomes in patients with left bundle-branch block, but the predictive value of 3D speckle-tracking echocardiography has not been investigated in these patients. The study retrospectively analyzed the association between 2D and 3D strains and left ventricular ejection fraction (LVEF) in patients with preserved or reduced LVEF. The results showed that 2D-GLS is predictive of maintaining LVEF in patients with preserved LVEF, while a lower 3D-global circumferential strain is associated with persistently reduced LVEF in patients with reduced LVEF.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Alberto Aimo, Alessandro Valleggi, Andrea Barison, Sara Salerni, Michele Emdin, Giovanni Donato Aquaro
Summary: In patients with non-ischaemic systolic heart failure and left bundle branch block, those displaying the wide pattern of left ventricular volume/time curves tend to have greater left ventricular dyssynchrony and worse outcomes, but show better response to cardiac resynchronization therapy.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Caio Assis Moura Tavares, Nelson Samesima, Felippe Lazar Neto, Ludhmila Abrahao Hajjar, Lucas C. Godoy, Eduardo Messias Hirano Padrao, Mirella Facin, Wilson Jacob Filho, Michael E. Farkouh, Carlos Alberto Pastore
Summary: The study concluded that using ECG criteria to assess LVH in patients with advanced age and true LBBB lacks diagnostic accuracy and clinical usefulness, and should not be routinely employed.
BMC CARDIOVASCULAR DISORDERS
(2021)
Article
Medicine, General & Internal
Luuk I. B. Heckman, Justin G. L. M. Luermans, Karol Curila, Antonius M. W. Van Stipdonk, Sjoerd Westra, Radovan Smisek, Frits W. Prinzen, Kevin Vernooy
Summary: The study shows that both LVSP and LBBP significantly improve ventricular dyssynchrony compared to RVSP, bringing values close to normal ventricular activation. Patients with left bundle branch capture during LBBP demonstrate the most significant decrease in QRS area.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Huang-Chung Chen, Wen-Hao Liu, Yung-Lung Chen, Wei-Chieh Lee, Yen-Nan Fang, Shaur-Zheng Chong, Mien-Cheng Chen
Summary: This study aimed to evaluate the impact of LBBP on LV MW in patients receiving pacemaker for bradyarrhythmia. It found that LBBP preserved more LV MW compared with NS-HBP and RVP in patients with mid-term (6-month) high ventricular pacing burden (>40%). Further studies are warranted to assess the association between LV MW and long-term clinical outcomes in LBBP with high ventricular pacing burden.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sijuan Sun, Xiaofeng Guo, Yiwei Chen, Jie Shen, Diqi Zhu, Zhifang Zhang, Lijun Fu, Wei Ji, Fen Li
Summary: This study aimed to investigate the effectiveness of left univentricular epicardial pacing in children with dilated cardiomyopathy and LBBB. The results showed that in young children with low body weight, left ventricular epicardial pacing still has a significant therapeutic effect if HF is caused by or related to LBBB.
Article
Cardiac & Cardiovascular Systems
Sijuan Sun, Xiaofeng Guo, Yiwei Chen, Jie Shen, Diqi Zhu, Zhifang Zhang, Lijun Fu, Wei Ji, Fen Li
Summary: The study demonstrates that left ventricular epicardial pacing has a significant effect in young children with low body weight if HF is caused by or related to LBBB.
Article
Cardiac & Cardiovascular Systems
Adrian Mirolo, Corentin Chaumont, Nathanael Auquier, Arnaud Savoure, Benedicte Godin, Florence Vandevelde, Helene Eltchaninoff, Frederic Anselme
Summary: This study aimed to assess the effects of left bundle branch area pacing (LBBAP) on mechanical synchrony parameters. The results showed that LBBAP effectively reduced QRS width and improved mechanical synchrony in patients with left bundle branch block.
