期刊
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
卷 278, 期 2-3, 页码 150-157出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijms.2008.04.019
关键词
Time-of-flight; Fragmentation; Phosphorylation; Metastable atom
资金
- National Institutes of Health [2R44RRO22926-02]
Fragmentation of phosphorylated peptide ions via interaction with electronically excited metastable argon atoms was studied in a linear trap-time-of-flight mass spectrometer. Doubly charged ions of phosphorylated peptides from an Enolase digest were produced by electrospray ionization and subjected to a metastable atom beam in the linear trap. The metastable argon atoms were generated using a glow-discharge source, An intensive series of c- and z-ions were observed in all cases, with the phosphorylation group intact. The formation of molecular radical cations with reduced charge indicated that an electron transfer from a highly excited metastable state of argon to the peptide cation occurred. Additionally, singly charged Bradykinin, Substance P and Fibrinopeptide A molecular ions were fragmented via interaction with electronically excited metastable helium atoms. The fragmentation mechanism was different in this case and involved Penning ionization. (c) 2008 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据