期刊
INTERNATIONAL JOURNAL OF IMMUNOGENETICS
卷 38, 期 6, 页码 519-523出版社
WILEY
DOI: 10.1111/j.1744-313X.2011.01035.x
关键词
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资金
- Coordinacion de Investigacion en Salud., CNIC Registro [2003-716-01172, 2005/1/I008]
- CONACYT, clave, Mexico City, Mexico [SALUD-2005-C02-14412]
- Fundacion IMSS, Mexico
Type 2 diabetes (T2D) is characterized by a chronic low-grade inflammatory state. SNP in Toll-like receptor (TLR) genes has been associated with impaired inflammatory response. We genotyped the TLR4/D299G, TLR4/T399I and TLR2/R753Q polymorphisms. Low frequency was found with no association with T2D, nevertheless the TLR2 SNP was associated with lower levels in HDL-cholesterol values.
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