Article
Multidisciplinary Sciences
Jordan Zeldin, Prem Prashant Chaudhary, Jacquelyn Spathies, Manoj Yadav, Brandon N. D'Souza, Mohammadali E. Alishahedani, Portia Gough, Jobel Matriz, Andrew J. Ghio, Yue Li, Ashleigh A. Sun, Lawrence F. Eichenfield, Eric L. Simpson, Ian A. Myles
Summary: Atopic dermatitis is a chronic inflammatory skin condition that is increasing in industrial nations, possibly due to environmental factors. The dysbiosis associated with atopic dermatitis may signal microbial adaptations to modern pollutants. R. mucosa has been found to fix nitrogen and produce protective glycerolipids and ceramide by-products, which can impact atopic dermatitis.
Review
Food Science & Technology
Hanieh Malmir, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This meta-analysis found that maternal fish consumption during pregnancy is associated with a lower risk of wheeze, eczema, and food allergy in children. However, there is no significant association between maternal fish consumption and the risk of offspring's asthma, allergic rhinitis, and inhalant allergy.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Allergy
Yongjin Zhong, Yuheng Zhang, Yan Wang, Ruijie Huang
Summary: This study found that maternal antibiotic use during pregnancy may increase the risk of childhood asthma/wheeze and eczema/atopic dermatitis, but not food allergy. Further studies with larger sample size and robust multivariable adjustment are needed to confirm these findings. The appropriate use of antibiotics during pregnancy is crucial, and healthcare professionals should exercise caution when prescribing antibiotics to pregnant women.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Article
Pediatrics
Hui Xing Lau, Michelle Zhi Ling Kee, Qai Ven Yap, Elizabeth Huiwen Tham, Yiong Huak Chan, Anne Eng Neo Goh, Oon Hoe Teoh, Johan Gunnar Eriksson, Keith M. Godfrey, Peter D. Gluckman, Yap Seng Chong, Jerry Kok Yen Chan, Hugo Van Bever, Bee Wah Lee, Lynette Pei-chi Shek, Michael J. Meaney, Evelyn Xiu Ling Loo
Summary: The study found that maternal distress during the preconception and pregnancy periods is associated with an increased risk of offspring wheeze in the first 18 months of life. Emotional and practical support from family can reduce the risk of offspring wheeze.
FRONTIERS IN PEDIATRICS
(2022)
Article
Nutrition & Dietetics
Emmy Fredriksson, Stina Boden, Magnus Domellof, Christina E. West
Summary: This study suggests that consumption of acidic fruit pouches in infancy is not associated with allergic phenotypes or IgE sensitization in early childhood.
Article
Nutrition & Dietetics
Lieve van Brakel, Carel Thijs, Ronald P. Mensink, Dieter Luetjohann, Jogchum Plat
Summary: This study aimed to investigate the relationship between non-cholesterol sterol concentrations in breast milk and allergic outcomes in two-year-old children. The results showed that higher concentrations of certain sterols in breast milk were associated with lower odds of eczema and allergic sensitization, but not wheeze.
Review
Nutrition & Dietetics
Jingqiu Su, Tian Li, Hua Pan
Summary: The study suggests that vitamin A supplementation is associated with increased risk of atopy but has no correlation with the incidence of wheezing. The findings provide evidence for effective management of fibrosis, but further research is needed to validate the results.
FRONTIERS IN NUTRITION
(2022)
Article
Environmental Sciences
Kristina Rueter, Anderson P. Jones, Aris Siafarikas, Paola Chivers, Susan L. Prescott, Debra J. Palmer
Summary: The study found that low levels of direct UV light exposure during early infancy were associated with the development of eczema, with children with eczema having significantly less exposure in the first few months of life compared to those without eczema.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Allergy
Hui Xing Lau, Zhaojin Chen, Yiong Huak Chan, Elizabeth Huiwen Tham, Anne Eng Neo Goh, Hugo Van Bever, Oon Hoe Teoh, Neerja Karnani, Peter D. Gluckman, Kok Hian Tan, Fabian Kok Peng Yap, Keith M. Godfrey, Johan G. Eriksson, Yap Seng Chong, Bee Wah Lee, Lynette Pei-Chi Shek, Evelyn Xiu Ling Loo
Summary: There is a strong association between early onset of eczema and early allergic sensitization. Early sensitization, especially to house dust mites, is associated with increased risks of developing wheeze and eczema.
WORLD ALLERGY ORGANIZATION JOURNAL
(2022)
Review
Behavioral Sciences
Cui Hong He, Jing Zhao, Ting Ting Zhu
Summary: The study found an association between allergic diseases and epilepsy, with an 81% increase in the prevalence of epilepsy among individuals with asthma and an incidence rate of 2.57 for epilepsy in patients with eczema. Further high-quality research is needed to confirm the association, understand the mechanism, and determine prevention opportunities.
EPILEPSY & BEHAVIOR
(2021)
Article
Allergy
Chikae Yamaguchi, Takeshi Ebara, Masaki Futamura, Yukihiro Ohya, Midori Asano
Summary: This study found that a history of wheezing and nose symptoms in children is associated with an increased risk of behavioral problems, especially conduct problems.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Article
Critical Care Medicine
Sadia Haider, Sara Fontanella, Anhar Ullah, Stephen Tumer, Angela Simpson, Graham Roberts, Clare S. Murray, John W. Holloway, John A. Curtin, Paul Cullinan, Syed Hasan Arshad, Guillem Hurault, Raquel Granell, Adnan Custovic
Summary: The study found significant variation in the patterns of eczema, wheeze, and rhinitis morbidity, with multimorbidity being rare but significantly overrepresented. Infantile eczema was associated with subsequent multimorbidity, but the majority of children with eczema did not progress to any comorbidities.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Kong Yen Liew, Nurain Irdayani Kamise, Hui Ming Ong, Poi Yi Aw Yong, Fahmida Islam, Ji Wei Tan, Chau Ling Tham
Summary: Allergic diseases are a global health burden, and the current available medications have side effects, poor perceived effectiveness, and high cost. Propolis, a natural herbal medicine with antioxidant, antimicrobial, and anticancer properties, has the potential to be a prophylactic or therapeutic option for allergic diseases. Preclinical studies have shown that propolis extracts have therapeutic effects on allergic inflammation, asthma, allergic rhinitis, atopic dermatitis, and food allergy by inhibiting mast cell and basophil activation. Clinically, propolis consumption as a supplement or adjunct therapy is safe and attenuates pathological conditions in asthma. Flavonoids and cinnamic acid derivatives in propolis contribute to its anti-allergic activities, but their presence varies in different propolis samples. Future studies should focus on the relationship between propolis's anti-allergic activity and its chemical contents.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
So-Lun Lee, Yu-Lung Lau, Wilfred Hing-Sang Wong, Lin-Wei Tian
Summary: The study found an increase in the prevalence of wheezing, allergic rhinitis, and eczema among school-aged children across the surveys. The most important associated risk factor identified was the increased prevalence of a parental history of atopy.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Dermatology
K. Mossing, A. Dizdarevic, A. Svensson, A. Sonesson
Summary: Patch testing can improve the quality of life of patients with allergic contact dermatitis, although additional interventions did not show significant improvement. Further research is needed to explore factors that affect quality of life in these patients and identify interventions to improve it.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Infectious Diseases
Bertram Kjerulff, Kathrine A. Kaspersen, Khoa M. Dinh, Jens Boldsen, Susan Mikkelsen, Lise T. Erikstrup, Erik Sorensen, Kaspar R. Nielsen, Mie T. Bruun, Henrik Hjalgrim, Ole B. Pedersen, Lise W. Thorner, Henrik Ullum, Sisse R. Ostrowski, Klaus Rostgaard, Carsten B. Pedersen, Torben Sigsgaard, Christian Erikstrup
Summary: Through a study of more than 120,000 Danish blood donors, it was found that smoking is closely related to an increased risk of infection, especially respiratory tract infection, abscesses, and skin infection. These findings indicate that we should pay more attention to the infection risk among smokers.
CLINICAL MICROBIOLOGY AND INFECTION
(2023)
Article
Environmental Sciences
Ole Raaschou-Nielsen, Sussie Antonsen, Esben Agerbo, Ulla A. Hvidtfeldt, Camilla Geels, Lise M. Frohn, Jesper H. Christensen, Torben Sigsgaard, Jurgen Brandt, Carsten B. Pedersen
Summary: This study found significant associations between natural cause mortality and sulfate particles (SO4--) and secondary organic aerosol (SOA) in PM2.5. Additionally, elemental carbon and mineral dust were found to be strongly associated with higher respiratory and lung cancer mortality.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Peripheral Vascular Disease
Hajir Al-Jorani, Richard Christian Jensen, Mikaela T. E. Jonasson, Anna Birukov, Anne Vibeke Schmedes, Henrik Thybo Christesen, Anja F. Dreyer, Tina K. Jensen, Dorte Glintborg, Boye L. Jensen, Marianne S. Andersen
Summary: This study investigated the association between maternal cortisol levels in the third trimester of pregnancy and offspring blood pressure (OBP). The results showed negative associations between maternal cortisol levels and OBP, specifically in boys. This suggests that maternal cortisol is not a risk factor for higher blood pressure in offspring up to the age of 5.
Article
Public, Environmental & Occupational Health
Eva Govarts, Liese Gilles, Laura Rodriguez Martin, Tiina Santonen., Petra Apel., Paula. Alvito, Elena. Anastasi, Helle Raun Andersen, Anna-Maria Andersson, Lenka Andryskova, Jean-Philippe Antignacj, Brice Appenzeller, Fabio Barbone, Zohar Barnett-Itzhaki, Robert Barouki, Tamar Berman, Wieneke Bil, Teresa Borges, Jurgen Buekers, Ana Canas-Portilla, Adrian Covaci, Zsofia Csako, Elly Den Hond, Darina Dvorakova, Lucia Fabelova, Tony Fletcherx, Hanne Frederiksen, Catherine Gabriel, Catherine Ganzleben, Thomas Goen, Thorhallur Halldorsson, Line S. Haug, Milena Horvat, Pasi Huuskonen, Medea Imboden, Marta Jagodic Hudobivnik, Beata Janasik, Natasa Janev Holcer, Spyros Karakitsios, Andromachi Katsonouri, Jana Klanova, Venetia Kokaraki, Tina Kold Jensen, Jani Koponen, Michelle Laeremans, Federica Laguzzi, Rosa Lange, Nora Lemke, Sanna Lignell, Anna Karin Lindroos, Joana Lobo Vicente, Mirjam Luijten, Konstantinos C. Makris, Darja Mazej, Lisa Melymuki, Matthieu Meslin, Hans Molar, Parisa Montazeri, Aline Murawski, Sonia Namorado, Lars Niemann, Stefanie Nabler, Baltazar Nunes, Kristin Olafsdottir, Lubica Palkovicova Murinova, Nafsika Papaioannou, Susana Pedraza-Diaz, Pavel Pileri, Veronika Plichta, Michael Poteser, Nicole Probst-Hensch, Loic Rambaud, Elke Rauscher-Gabernig, Katarina Rausova, Sylvie Remy, Margaux Riou, Valentina Rosolen, Christophe Rousselle, Maria Rather, Denis Sarigiannis, Maria J. Silva, Zdenka Slejkovec, Janja Snoj Tratnik, Anja Stajnko, Tamas Szigeti, Jose V. Tarazona, Cathrine Thomsen, Ziga Tkalec, Hanna Tolonen, Tomas Trnovec, Maria Uhl, An Van Nieuwenhuyse, Elsa Vasco, Veerle J. Verheyen, Susana Viegas, Anne Marie Vinggaard, Nina Vogel, Katrin Vorkamp, Wojciech Wasowicz, Till Weber, Sona Wimmerova, Marjolijn Woutersen, Philipp Zimmermann, Martin Zvonari, Holger Koch, Marike Kolossa-Gehring, Marta Esteban Lopez, Argelia Castano, Lorraine Stewartx, Ovnair Sepaix, Greet Schoeters
Summary: As part of the European Human Biomonitoring Initiative, a human biomonitoring survey was conducted in 23 countries to produce comparable data for the EU. The survey utilized existing HBM capacity in Europe and aligned national or regional studies under the HBM4EU program. The survey included over 10,000 participants from different age groups and measured various biomarkers to assess exposure levels to different chemicals. The data obtained can be used as a reference for global comparison, evaluate the effectiveness of the European Commission's chemical strategy, and guide policy-making.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Nina Vogel, Phillipp Schmidt, Rosa Lange, Antje Gerofke, Amrit K. Sakhi, Line S. Haug, Tina Kold Jensen, Hanne Frederiksen, Tamas Szigeti, Zsofia Csako, Lubica Palkovicova Murinova, Miroslava Sidlovska, Beata Janasik, Wojciech Wasowicz, Janja Snoj Tratnik, Darja Mazej, Catherine Gabriel, Spyros Karakitsios, Fabio Barbonem, Valentina Rosolen, Loic Rambaud, Margaux Riou, Aline Murawski, Daan Leseman, Gudrun Koppen, Adrian Covaci, Sanna Lignell, Anna Karin Lindroos, Martin Zvonar, Lenka Andryskova, Lucia Fabelova, Denisa Richterova, Milena Horvatj, Tina Kosjekj, Denis Sarigiannis, Marios Maroulis, Susana Pedraza-Diaz, Ana Canas, Veerle J. Verheyen, Michiel Bastiaensen, Liese Gilles, Greet Schoeters, Marta Esteban-Lopez, Argelia Castano, Eva Govarts, Holger M. Kochx, Marike Kolossa-Gehring
Summary: Phthalates are widely used as plasticizers for PVC and are associated with adverse effects on the reproductive system. The HBM4EU Aligned Studies have investigated the exposure to ten phthalates and the substitute chemical DINCH in European children and adolescents. The study provides detailed data on exposure levels and differences across European regions, as well as comparisons to biomonitoring guidance values.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Frida Bejder Klausen, Ali Amidi, Soren K. Kjaergaard, Vivi Schlunssen, Peter Ravn, Kirsten Ostergaard, Vibeke Heitmann Gutzke, Marianne Glasius, Therese Koops Gronborg, Stefan Nygaard Hansen, Robert Zachariae, Pawel Wargocki, Torben Sigsgaard
Summary: This study aimed to investigate the effect of CO2 during sleep on next-morning cognitive performance in young schoolchildren. The results showed no significant impact of CO2 on cognitive performance during sleep, but a slightly lower sleep efficiency was observed with high CO2 concentrations. Therefore, replication studies in actual bedrooms controlling for other external factors are needed to draw more general conclusions.
INTERNATIONAL JOURNAL OF OCCUPATIONAL MEDICINE AND ENVIRONMENTAL HEALTH
(2023)
Article
Endocrinology & Metabolism
Hanne Mumm, Anja Fenger Dreyer, Dorthe Bleses, Dorte Glintborg, Tina Kold Jensen, Henriette Boye, Fabio Trecca, Marianne Skovsager Andersen
Summary: This prospective observational study aimed to evaluate the association between maternal third trimester cortisol and early longitudinal offspring language development, and to test whether there were sex differences in the association. The results showed that higher maternal cortisol levels in the third trimester were positively associated with early language development in children, with boys showing effects on productive vocabulary and girls showing effects on receptive vocabulary.
JOURNAL OF NEUROENDOCRINOLOGY
(2023)
Article
Neurosciences
Mikkel Vilmand, Iben Have Beck, Niels Bilenberg, Anna-Maria Andersson, Anders Juul, Greet Schoeters, Henriette Boye, Hanne Frederiksen, Tina Kold Jensen
Summary: This study investigated the association between prenatal and concurrent exposure to phthalates and IQ in 7-year-old children. The results showed that high concentrations of metabolites of di(2-ethylhexyl) phthalate were associated with decreased IQ in children. This suggests that exposure to phthalates may be harmful to child neurodevelopment.
NEUROTOXICOLOGY AND TERATOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Marta A. Kisiel, Oscar Arnfelt, Eva Lindberg, Oscar Jogi, Andrei Malinovschi, Ane Johannessen, Bryndis Benediktsdottir, Karl Franklin, Mathias Holm, Francisco Gomez Real, Torben Sigsgaard, Thorarinn Gislason, Lars Modig, Christer Janson
Summary: This study found that abdominal and general obesity are associated with respiratory symptoms and diseases in adults. In women, both types of obesity are linked to asthma and chronic obstructive pulmonary disease, whereas this association is not present in men.
RESPIRATORY MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Henriette. T. Horsdal, Marianne. G. Pedersen, Jorg Schullehner, Cecilie S. Ostergaard, John J. Mcgrath, Esben Agerbo, Allan Timmermann, Ane Marie Closter, Jorgen Brandt, Jesper H. Christensen, Lise M. Frohn, Camilla Geels, Matthias Ketzel, Jibran Khan, Pia Orby, Yulia Olsen, Gregor Levin, Jens-Christian Svenning, Kristine Engemann, Steen Gyldenkaerne, Birgitte Hansen, Ole Hertel, Clive E. Sabel, Christian Erikstrup, Torben Sigsgaard, Carsten B. Pedersen
Summary: The aim of this study is to provide an overview of nationwide environmental data in Denmark and its potential linkage to individual-level records to promote research on the impact of the local environment on human health. Researchers in Denmark can conduct large population-based studies using nationally complete population and health registries. Linking environmental data to individuals enables new possibilities for studying the health effects of the social, built, and physical environment.
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
(2023)
Letter
Allergy
Simon Hoj, Hanieh Meteran, Simon Francis Thomsen, Torben Sigsgaard, Howraman Meteran
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Toxicology
Karin Rosenkilde Laursen, Nichlas Vous Christensen, Frans A. A. Mulder, Jorg Schullehner, Hans Jurgen Hoffmann, Annie Jensen, Peter Moller, Steffen Loft, Anna-Carin B. Olin, Berit Rasmussen, Bernadette Rosati, Bo Strandberg, Marianne Glasius, Merete Bilde, Torben Sigsgaard, Climate Chamber Grp
Summary: This study investigated the effects of emissions from cooking and candle burning on inflammatory changes in individuals with mild asthma. The results showed that cooking emissions significantly increased levels of oxidatively damaged DNA and lipids in the blood, while candle emissions had a minimal impact on the respiratory system.
PARTICLE AND FIBRE TOXICOLOGY
(2023)
Article
Endocrinology & Metabolism
Jonas Jannick Andreasen, Bror Bastian Tobiasen, Richard Christian Jensen, Henriette Boye, Tina Kold Jensen, Niels Bilenberg, Marianne Skovsager Andersen, Dorte Glintborg
Summary: The cortisol level of pregnant women during the third trimester is associated with the traits of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in their offspring. This association is significant at three years of age but not at five years of age.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Environmental Sciences
Lisa Ernle, Nijing Wang, Gabriel Bekoe, Glenn Morrison, Pawel Wargocki, Charles J. J. Weschler, Jonathan Williams
Summary: Proton transfer reaction-mass spectrometry (PTR-MS) is commonly used for monitoring volatile organic compounds in indoor and outdoor environments. However, the use of mass-to-charge ratio m/z 69.07 as an indicator of indoor isoprene can be affected by the presence of aldehydes, especially when ozone levels are high.
ENVIRONMENTAL SCIENCE-ATMOSPHERES
(2023)
Article
Public, Environmental & Occupational Health
Charlotte Gabel, Grethe Elholm, Mia Kruse Rasmussen, Thea Hauge Broholt, Stina Rask Jensen, Steffen Petersen, Torben Sigsgaard
Summary: The HOME-Health study aims to investigate residents' seasonal health status, perception of indoor environmental quality (IEQ), IEQ-related behaviors and practices, and objective measurements of indoor air quality (IAQ) before and after building energy renovation (BER). By combining quantitative and qualitative data, the study is expected to provide in-depth knowledge and evidence for future renovation projects in social housing areas.
ENVIRONMENTAL HEALTH INSIGHTS
(2023)
Article
Public, Environmental & Occupational Health
Dewan Muhammad Shoaib, Tanvir Ahmed, Kazy Farhat Tabassum, Mehedi Hasan, Fazle Sharior, Mahbubur Rahman, Makfie Farah, Md Azizur Rahman, Alauddin Ahmed, James B. Tidwell, Mahbub-Ul Alam
Summary: An intervention was implemented in Bangladesh during COVID-19 to reduce occupational health risks for waste and sanitation workers. The intervention involved training and distribution of personal protective equipment (PPE). The study found that the intervention improved workers' knowledge, attitude, and practice regarding PPE usage.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Andreas Kortenkamp, Olwenn Martin, Eleni Iacovidou, Martin Scholze
Summary: The European Food Safety Authority's downward revision of the Health-based Guidance Value for bisphenol A (BPA) has led to disagreements with other regulatory agencies, particularly the German Federal Institute for Risk Assessment. The differing views between EFSA and BfR are driven by their respective selection of endpoints and study evaluation systems, as well as their acceptance or refusal of immunotoxic effects as a basis for establishing a Health-based Guidance Value.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Shizhen He, Bjorn Lundberg, Jenny Hallberg, Susanna Klevebro, Goran Pershagen, Kristina Eneroth, Erik Melen, Matteo Bottai, Olena Gruzieva
Summary: Early life air pollution exposure and abnormal inflammation-related protein profiles may interact synergistically towards lower lung function in infants.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Paulien Cleys, Emilie Hardy, Yu Ait Bamai, Giulia Poma, Adam Cseresznye, Govindan Malarvannan, Paul T. J. Scheepers, Susana Viegas, Simo P. Porras, Tiina Santonen, Lode Godderis, Jelle Verdonck, Katrien Poels, Carla Martins, Maria Joao Silva, Henriqueta Louro, Inese Martinsone, Lasma Akulova, An van Nieuwenhuyse, Martien Graumans, Selma Mahiout, Radu Corneliu Duca, Adrian Covaci
Summary: The aim of this study was to assess the exposure of e-waste workers to phthalates and alternative plasticizers. The results showed that e-waste workers had higher urinary concentrations of phthalates and metabolites compared to non-occupationally exposed controls. However, no significant differences were found between pre-and post-shift concentrations in the e-waste workers.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Karolina Bralewska
Summary: This review study examines the concentrations of various air pollutants in fire stations, identifies the limitations and strengths of existing research, identifies research gaps and challenges, and suggests potential solutions for reducing firefighter exposure to air pollution at fire stations.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)