Review
Environmental Sciences
Xin Wang, Rajat Nag, Nigel P. Brunton, Md Abu Bakar Siddique, Sabine M. Harrison, Frank J. Monahan, Enda Cummins
Summary: This review focuses on the contamination of meat products by bisphenol A (BPA) and its potential health risks. BPA has been widely detected in canned and non-canned meat products, with the main source being the migration from can coatings. The European Food Safety Authority has proposed to lower the tolerable daily intake of BPA, indicating the need to address potential health risks. The study also highlights the data gaps and the importance of improving food safety in the meat industry through a unified risk assessment strategy.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Iris Reina-Perez, Alicia Olivas-Martinez, Vicente Mustieles, Elena Salamanca-Fernandez, Jose Manuel Molina-Molina, Nicolas Olea, Mariana F. Fernandez
Summary: This study investigated the combined effect of bisphenol A (BPA) and its substitutes, bisphenol F (BPF) and S (BPS), on the adipogenic differentiation of human adipose-derived stem cells (hASCs). The researchers found that the mixture of bisphenols promoted lipid accumulation in the cells in a dose-dependent manner, with a maximal response at 10 μM. The effect was mediated by the estrogen receptor, and the mixture also altered the expression of adipogenic markers in a non-monotonic dose-response pattern.
Article
Food Science & Technology
Iris Reina-Perez, Alicia Olivas-Martinez, Vicente Mustieles, Francisco Javier Ruiz-Ojeda, Jose Manuel Molina-Molina, Nicolas Olea, Mariana F. Fernandez
Summary: BPF and BPS were found to increase intracellular lipid accumulation and affect gene expression related to adipogenesis in human adipose-derived stem cells; their obesogenic effects may involve multiple pathways. This study reveals for the first time the obesogenic potential of BPF in human adipose-derived stem cells.
FOOD AND CHEMICAL TOXICOLOGY
(2021)
Article
Environmental Sciences
Kamila Rybczynska-Tkaczyk, Bartosz Skora, Konrad A. Szychowski
Summary: The aim of this study was to determine the toxicity of bisphenol A (BPA) and its derivatives on various organisms. The results showed that BPA, BPS, and BPF exhibited high toxicity on bacteria, reaching concentrations of 0.018-0.031 mg/L. These compounds also showed genotoxicity and cytotoxicity effects on human cells, as well as phytotoxicity effects on plants. The findings suggest that BPA and its derivatives have a negative impact on living organisms through apoptosis and genotoxic mechanisms.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Endocrinology & Metabolism
Yuyao Yang, Xiaoyue Bai, Juan Lu, Ronghao Zou, Rui Ding, Xiaohui Hua
Summary: This meta-analysis investigates the association between environmental endocrine disruptors (EEDs) and thyroid cancer. The results reveal that certain EEDs, such as PBDEs, PAEs, and heavy metals, are associated with an increased risk of thyroid cancer. However, further studies are needed to confirm these findings and explore the underlying mechanisms.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Francesco Sessa, Rita Polito, Vincenzo Monda, Alessia Scarinci, Monica Salerno, Marco Carotenuto, Giuseppe Cibelli, Anna Valenzano, Angelo Campanozzi, Maria Pina Mollica, Marcellino Monda, Giovanni Messina
Summary: The study evaluated urinary BPA levels in an Italian pediatric cohort over a 6-month period, finding a reduction in BPA levels in a group following a plastic-free diet regimen in a school canteen setting. The results demonstrate a connection between BPA levels and food packaging, with significant reductions seen in the group with the altered diet plan.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Tasnia Sharin, Helina Gyasi, Kim L. Williams, Doug Crump, Jason M. O'Brien
Summary: This study investigated the toxicological effects of two BPA replacements, DD-70 and BPAF, on avian embryos. The results showed that these substitutes had varying impacts on embryonic viability, development, and hepatic gene expression. Further research is needed to fully understand the implications of using these chemicals as BPA alternatives.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Endocrinology & Metabolism
Leticia Heras-Gonzalez, Diana Espino, Maria Jose Jimenez-Casquet, Alejandro Lopez-Moro, Fatima Olea-Serrano, Miguel Mariscal-Arcas
Summary: This study aimed to investigate the influence of BPA exposure, saliva analysis, and daily physical activity on the risk of overweight/obesity in schoolchildren from southern Spain. The results showed that body fat composition, not walking to and from school, lesser energy expenditure in sedentary activities, greater energy expenditure in sports, and exposure to BPA from dental sealants/composites significantly influenced the risk of overweight/obesity. Further research on the negative health effects of endocrine disruption in children is needed.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Fabiana Oliviero, Alice Marmugi, Catherine Viguie, Veronique Gayrard, Nicole Picard-Hagen, Laila Mselli-Lakhal
Summary: Metabolic diseases have a significant impact on public health, with environmental factors and lifestyle playing a crucial role in their development. BPA, a commonly used environmental chemical, has been associated with various physiological and health disorders. Despite the ban on BPA, its structural analogs are still widely used as substitutes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Toxicology
Anja Kodila, Nina Franko, Marija Sollner Dolenc
Summary: Bisphenol A (BPA) is a known endocrine disruptor found in many consumer products. Due to safety concerns, industry has started using new BPA analogues, which have similar properties but are less studied. Some BPA analogues have been shown to cause endocrine disruption, with effects on various nuclear receptors. The European Food Safety Authority has reduced the tolerable daily intake of BPA, leading to a comprehensive review of the immunomodulatory activity of BPA analogues, which suggests that they can impact the immune system and contribute to immune-mediated conditions.
ARCHIVES OF TOXICOLOGY
(2023)
Review
Environmental Sciences
Ravi Naidu, Bhabananda Biswas, Ian R. Willett, Julian Cribb, Brajesh Kumar Singh, C. Paul Nathanail, Frederic Coulon, Kirk T. Semple, Kevin C. Jones, Adam Barclay, Robert John Aitken
Summary: Anthropogenic chemical pollution has the potential to threaten humanity's environmental health significantly; however, global understanding of this issue remains fragmented. There are serious gaps in our understanding of the scale of the threat and the risks posed by the dispersal, mixture, and recombination of chemicals in the wider environment. Despite the existence of pollution control measures, they are often not being implemented at the necessary rate to prevent chronic and acute effects on human health.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Poonam Sharma, Reena Vishwakarma, Sunita Varjani, Krishna Gautam, Vivek K. Gaur, Alvina Farooqui, Raveendran Sindhu, Parameswaran Binod, Mukesh Kumar Awasthi, Preeti Chaturvedi, Ashok Pandey
Summary: With the increased use of plastic, the accumulation of degraded plastic products like microplastics or plastic additives such as Bisphenol A (BPA) is also increasing. Enzymes and microorganisms have been studied for their ability to reduce the toxicity of BPA and degrade different classes of plastic additives. Meta-omics approaches have been employed to identify the active microbiota and microbial dynamics involved in the degradation process. It is important to investigate the impact of processing activities on the distribution of BPA in food and take measures to limit its presence in the food industry.
ENVIRONMENTAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Ana Lopez-Moreno, Angel Ruiz-Moreno, Jesus Pardo-Cacho, Klara Cerk, Alfonso Torres-Sanchez, Pilar Ortiz, Marina Ubeda, Margarita Aguilera
Summary: Integrated data from molecular and improved culturomics studies reveal the dysbiosis of the gut microbiome triggered by xenobiotics, such as obesity and metabolic disorders. The research focused on the xenobiotic obesogen, Bisphenol A (BPA), and found that certain bacterial taxa, particularly Bacillus spp., exhibited higher BPA biodegradation potential in overweight/obese individuals compared to those with normal weight.
Review
Pharmacology & Pharmacy
Ylenia Della Rocca, Enrico Matteo Traini, Francesca Diomede, Luigia Fonticoli, Oriana Trubiani, Alessia Paganelli, Jacopo Pizzicannella, Guya Diletta Marconi
Summary: Bisphenol A (BPA), an endocrine disrupting chemical (EDC), is believed to be involved in the pathogenesis of various diseases, including immune-mediated disorders, type-2 diabetes mellitus, cardiovascular diseases, and cancer. This review aims to analyze the mechanism of action of BPA, with a specific focus on mesenchymal stromal/stem cells (MSCs) and adipogenesis. The uses of BPA in dental, orthopedic, and industrial fields will be assessed, as well as the impact on different pathological or physiological conditions and related molecular pathways.
Article
Environmental Sciences
Sheng Chen, Xiaodong Li, Han Li, Siliang Yuan, Jun Li, Chunsheng Liu
Summary: Limited studies have been conducted to evaluate the effects of BPA and BPAF on low trophic level animals like Daphnia magna. Exposure to BPA and BPAF resulted in significant effects on the survival, reproduction, and gene expression of D. magna, with lower concentrations of BPAF causing decreased fecundity and both BPA and BPAF affecting the body length and swimming speed of offspring.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Food Science & Technology
Sophal Cheat, Philippe Pinton, Anne-Marie Cossalter, Juliette Cognie, Maria Vilarino, Patrick Callu, Isabelle Raymond-Letron, Isabelle P. Oswald, Martine Kolf-Clauw
FOOD AND CHEMICAL TOXICOLOGY
(2016)
Review
Cell Biology
Claire Beausoleil, Claude Emond, Jean-Pierre Cravedi, Jean-Philippe Antignac, Martine Applanat, Brice R. Appenzeller, Remy Beaudouin, Luc P. Belzunces, Marie-Chantal Canivenc-Lavier, Nicolas Chevalier, Cecile Chevrier, Elisabeth Elefant, Florence Eustache, Rene Habert, Martine Kolf-Clauw, Brigitte Le Magueresse-Battistoni, Sakina Mhaouty-Kodja, Christophe Minier, Luc Multigner, Henri Schroeder, Patrick Thonneau, Catherine Viguie, Francois Pouzaud, Jean-Nicolas Ormsby, Christophe Rousselle, Lauranne Verines-Jouin, Elodie Pasquier, Cecile Michel
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2018)
Article
Veterinary Sciences
Marcel Gyger, Manuel Berdoy, Ismene Dontas, Martine Kolf-Clauw, Ana Isabel Santos, Mats Sjoquist
LABORATORY ANIMALS
(2019)
Review
Cell Biology
Martine Perrot-Applanat, Martine Kolf-Clauw, Cecile Michel, Claire Beausoleil
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2018)
Article
Multidisciplinary Sciences
Imourana Alassane-Kpembi, Juliana Rubira Gerez, Anne-Marie Cossalter, Manon Neves, Joelle Laffitte, Claire Naylies, Yannick Lippi, Martine Kolf-Clauw, Ana Paula L. Bracarense, Philippe Pinton, Isabelle P. Oswald
SCIENTIFIC REPORTS
(2017)
Article
Food Science & Technology
Gilles Riviere, Julien Jean, Sebastien Gorecki, Marion Hulin, Martine Kolf-Clauw, Cyril Feidt, Nicole Picard-Hagen, Paule Vasseur, Bruno Le Bizec, Veronique Sirot
FOOD AND CHEMICAL TOXICOLOGY
(2019)
Article
Food Science & Technology
Vittorio Silano, Jose Manuel Barat, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Alicja Mortensen, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Beat J. Brueschweiler, Laurence Castle, Jean-Pierre Cravedi, Emma Di Consiglio, Roland Franz, Nicole Hellwig, Martine Kolf-Clauw, Maria Rosaria Milana, Karla Pfaff, Maria de Fatima Tavares Pocas, Kettil Svensson, Detlef Woelfle, Eric Barthelemy, Gilles Riviere
Article
Food Science & Technology
Vittorio Silano, Jose Manuel Barat Baviera, Claudia Bolognesi, Beat Johannes Bruschweiler, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Alicja Mortensen, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Laurence Castle, Jean-Pierre Cravedi, Martine Kolf-Clauw, Maria Rosaria Milana, Karla Pfaff, Maria de Fatima, Kettil Pocas, Kettil Svensson, Detlef Wolfle, Eric Barthelemy, Gilles Riviere
Article
Food Science & Technology
Vittorio Silano, Claudia Bolognesi, Kevin Chipman, Jean-Pierre Cravedi, Karl-Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gurtler, Trine Husoy, Sirpa Karenlampi, Wim Mennes, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fatima Tavares Pocas, Christina Tlustos, Detlef Wolfle, Holger Zorn, Martine Kolf-Clauw, Eugenia Lampi, Kettil Svensson, Ellen Van Haver, Laurence Castle
Article
Food Science & Technology
Vittorio Silano, Claudia Bolognesi, Jean-Pierre Cravedi, Karl-Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gurtler, Trine Husoy, Sirpa Karenlampi, Wim Mennes, Maria Rosaria Milana, Andre Penninks, Andrew Smith, Maria de Fatima Tavares Pocas, Christina Tlustos, Detlef Wolfle, Holger Zorn, Corina-Aurelia Zugravu, Martine Kolf-Clauw, Eugenia Lampi, Kettil Svensson, Cristina Croera, Laurence Castle
Article
Biotechnology & Applied Microbiology
Sophal Cheat, Isabelle P. Oswald, Martine Kolf-Clauw
FOODBORNE DISEASES: CASE STUDIES OF OUTBREAKS IN THE AGRI-FOOD INDUSTRIES
(2016)
Article
Food Science & Technology
Vittorio Silano, Claudia Bolognesi, Kevin Chipman, Jean-Pierre Cravedi, Karl-Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gurtler, Trine Husoy, Sirpa Karenlampi, Wim Mennes, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fatima Tavares Pocas, Christina Tlustos, Detlef Woelfle, Holger Zorn, Martine Kolf-Clauw, Eugenia Lampi, Kettil Svensson, Alexandros Lioupis, Laurence Castle
Article
Food Science & Technology
Vittorio Silano, Claudia Bolognesi, Kevin Chipman, Jean-Pierre Cravedi, Karl-Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob, Rainer Gurtler, Trine Husoy, Sirpa Kaerenlampi, Wim Mennes, Maria Rosaria Milana, Karla Pfaff, Gilles Riviere, Jannavi Srinivasan, Maria de Fatima Tavares Pocas, Christina Tlustos, Detlef Wolfle, Holger Zorn, Martine Kolf-Clauw, Eugenia Lampi, Kettil Svensson, Alexandros Lioupis, Laurence Castle
Article
Food Science & Technology
Vittorio Silano, Jose Manuel Barat Baviera, Claudia Bolognesi, Beat Johannes Brueschweiler, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Alicja Mortensen, Gilles Riviere, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Jean-Pierre Cravedi, Martine Kolf-Clauw, Roland Franz, Maria Rosaria Milana, Karla Pfaff, Maria de Fatima Tavares Pocas, Kettil Svensson, Detlef Woelfle, Cristina Croera, Laurence Castle
Article
Food Science & Technology
Vittorio Silano, Jose Manuel Barat Baviera, Claudia Bolognesi, Beat Johannes Brueschweiler, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Alicja Mortensen, Gilles Riviere, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Martine Kolf-Clauw, Jean-Pierre Cravedi, Roland Franz, Maria Rosaria Milana, Karla Pfaff, Maria de Fatima Tavares Pocas, Kettil Svensson, Detlef Woelfle, Alexandros Lioupis, Laurence Castle
Article
Public, Environmental & Occupational Health
Dewan Muhammad Shoaib, Tanvir Ahmed, Kazy Farhat Tabassum, Mehedi Hasan, Fazle Sharior, Mahbubur Rahman, Makfie Farah, Md Azizur Rahman, Alauddin Ahmed, James B. Tidwell, Mahbub-Ul Alam
Summary: An intervention was implemented in Bangladesh during COVID-19 to reduce occupational health risks for waste and sanitation workers. The intervention involved training and distribution of personal protective equipment (PPE). The study found that the intervention improved workers' knowledge, attitude, and practice regarding PPE usage.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Andreas Kortenkamp, Olwenn Martin, Eleni Iacovidou, Martin Scholze
Summary: The European Food Safety Authority's downward revision of the Health-based Guidance Value for bisphenol A (BPA) has led to disagreements with other regulatory agencies, particularly the German Federal Institute for Risk Assessment. The differing views between EFSA and BfR are driven by their respective selection of endpoints and study evaluation systems, as well as their acceptance or refusal of immunotoxic effects as a basis for establishing a Health-based Guidance Value.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Shizhen He, Bjorn Lundberg, Jenny Hallberg, Susanna Klevebro, Goran Pershagen, Kristina Eneroth, Erik Melen, Matteo Bottai, Olena Gruzieva
Summary: Early life air pollution exposure and abnormal inflammation-related protein profiles may interact synergistically towards lower lung function in infants.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Paulien Cleys, Emilie Hardy, Yu Ait Bamai, Giulia Poma, Adam Cseresznye, Govindan Malarvannan, Paul T. J. Scheepers, Susana Viegas, Simo P. Porras, Tiina Santonen, Lode Godderis, Jelle Verdonck, Katrien Poels, Carla Martins, Maria Joao Silva, Henriqueta Louro, Inese Martinsone, Lasma Akulova, An van Nieuwenhuyse, Martien Graumans, Selma Mahiout, Radu Corneliu Duca, Adrian Covaci
Summary: The aim of this study was to assess the exposure of e-waste workers to phthalates and alternative plasticizers. The results showed that e-waste workers had higher urinary concentrations of phthalates and metabolites compared to non-occupationally exposed controls. However, no significant differences were found between pre-and post-shift concentrations in the e-waste workers.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Karolina Bralewska
Summary: This review study examines the concentrations of various air pollutants in fire stations, identifies the limitations and strengths of existing research, identifies research gaps and challenges, and suggests potential solutions for reducing firefighter exposure to air pollution at fire stations.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2024)