Histone methylation and V(D)J recombination

The Epigenetic Profile of Ig Genes Is Dynamically Regulated during B Cell Differentiation and Is Modulated by Pre-B Cell Receptor Signaling

(2014) C.-R. Xu et al.   JOURNAL OF IMMUNOLOGY

Modeling of the RAG Reaction Mechanism

(2014) Amjad Askary et al.   Cell Reports

Complementary regulation of early B-lymphoid differentiation by genetic and epigenetic mechanisms

(2013) Takafumi Yokota et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Deep Sequencing of the Murine Igh Repertoire Reveals Complex Regulation of Nonrandom V Gene Rearrangement Frequencies

(2013) N. M. Choi et al.   JOURNAL OF IMMUNOLOGY

Localized DNA Demethylation at Recombination Intermediates during Immunoglobulin Heavy Chain Gene Assembly

(2013) Roza Selimyan et al.   PLOS BIOLOGY

Histone H3R2 Symmetric Dimethylation and Histone H3K4 Trimethylation Are Tightly Correlated in Eukaryotic Genomes

(2012) Chih-Chi Yuan et al.   Cell Reports

V(D)J Recombination: Mechanisms of Initiation

(2011) David G. Schatz et al.   Annual Review of Genetics

Epigenetic regulation of antigen receptor gene rearrangement

(2011) Ann J Feeney   CURRENT OPINION IN IMMUNOLOGY

VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity

(2011) Michele D Kassmeier et al.   EMBO JOURNAL

Coupling of V(D)J Recombination to the Cell Cycle Suppresses Genomic Instability and Lymphoid Tumorigenesis

(2011) Li Zhang et al.   IMMUNITY

The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3

(2011) Jessica M. Jones et al.   IMMUNOLOGY LETTERS

Mechanistic Basis for RAG Discrimination between Recombination Sites and the Off-Target Sites of Human Lymphomas

(2011) N. Shimazaki et al.   MOLECULAR AND CELLULAR BIOLOGY

The RAG2 C terminus suppresses genomic instability and lymphomagenesis

(2011) Ludovic Deriano et al.   NATURE

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci

(2010) Yanhong Ji et al.   CELL

Transcriptional Activity Affects the H3K4me3 Level and Distribution in the Coding Region

(2010) C. Y. Okitsu et al.   MOLECULAR AND CELLULAR BIOLOGY

The RING Domain of RAG1 Ubiquitylates Histone H3: A Novel Activity in Chromatin-Mediated Regulation of V(D)J Joining

(2010) Ursula Grazini et al.   MOLECULAR CELL

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination

(2010) G. J. Grundy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal and spatial regulatory functions of the V(D)J recombinase

(2010) Stephen Desiderio   SEMINARS IN IMMUNOLOGY

RAGs’ eye view of the immunoglobulin heavy chain gene locus

(2010) Ramesh Subrahmanyam et al.   SEMINARS IN IMMUNOLOGY

The roles of the RAG1 and RAG2 “non-core” regions in V(D)J recombination and lymphocyte development

(2009) Jessica M. Jones et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Molecular Mechanism Underlying RAG1/RAG2 Synaptic Complex Formation

(2009) Luda S. Shlyakhtenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation

(2009) Tirtha Chakraborty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: SWI/SNF Mediates Antisense Igh Transcription and Locus-Wide Accessibility in B Cell Precursors

(2009) O. A. Osipovich et al.   JOURNAL OF IMMUNOLOGY

A Non-Sequence-Specific DNA Binding Mode of RAG1 Is Inhibited by RAG2

(2009) Shuying Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

H3K4me3 Stimulates the V(D)J RAG Complex for Both Nicking and Hairpinning in trans in Addition to Tethering in cis: Implications for Translocations

(2009) Noriko Shimazaki et al.   MOLECULAR CELL

Initial Stages of V(D)J Recombination: The Organization of RAG1/2 and RSS DNA in the Postcleavage Complex

(2009) Gabrielle J. Grundy et al.   MOLECULAR CELL

Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity

(2008) Albert G. Tsai et al.   CELL

How chromatin remodelling allows shuffling of immunoglobulin heavy chain genes

(2008) Adam J. Bowen et al.   Molecular BioSystems

Activation of 12/23-RSS-Dependent RAG Cleavage by hSWI/SNF Complex in the Absence of Transcription

(2008) Hansen Du et al.   MOLECULAR CELL

PHD fingers in human diseases: Disorders arising from misinterpreting epigenetic marks

(2008) Lindsey A. Baker et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

RAG2's non-core domain contributes to the ordered regulation of V(D)J recombination

(2008) John D. Curry et al.   NUCLEIC ACIDS RESEARCH

Reciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5

(2008) C.-R. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA