von Willebrand factor: at the crossroads of bleeding and thrombosis

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor

(2011) J. T. B. Crawley et al.   BLOOD

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

(2011) C. M. Pruss et al.   BLOOD

Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region

(2011) X. Fu et al.   BLOOD

How I treat the acquired von Willebrand syndrome

(2011) A. Tiede et al.   BLOOD

Histones induce rapid and profound thrombocytopenia in mice

(2011) T. A. Fuchs et al.   BLOOD

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels

(2011) Guillemette Antoni et al.   BMC Medical Genetics

Pathophysiology of acquired von Willebrand disease: a concise review

(2011) Shrimati Shetty et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Local Elongation of Endothelial Cell-anchored von Willebrand Factor Strings Precedes ADAMTS13 Protein-mediated Proteolysis

(2011) Karen De Ceunynck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice

(2011) Junmei Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein

(2011) R. SCHNEPPENHEIM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Biology and physics of von Willebrand factor concatamers

(2011) T. A. SPRINGER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review

(2011) M. C. VAN SCHIE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Management of Inheritedvon Willebrand Disease in Italy: Results from the Retrospective Study on 1234 Patients

(2011) Augusto Federici et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Bleeding tendency and efficacy of anti-haemorrhagic treatments in patients with type 1 von Willebrand disease and increased von Willebrand factor clearance

(2011) Alberto Tosetto et al.   THROMBOSIS AND HAEMOSTASIS

Binding of von Willebrand Factor to Collagen and Glycoprotein Ibα, But Not to Glycoprotein IIb/IIIa, Contributes to Ischemic Stroke in Mice—Brief Report

(2010) Simon F. De Meyer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B

(2010) J. Rayes et al.   BLOOD

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

(2010) A. Brill et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Effect of Genetic Variations in Syntaxin-Binding Protein-5 and Syntaxin-2 on von Willebrand Factor Concentration and Cardiovascular Risk

(2010) Janine E. van Loon et al.   Circulation-Cardiovascular Genetics

ADAMTS-13: double trouble for von Willebrand factor

(2010) P. J. LENTING et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Disulfide bond reduction of von Willebrand factor by ADAMTS-13

(2010) H.-C. YEH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD

(2010) V. H. FLOOD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of von Willebrand factor-platelet interactions

(2010) Julie Pegon et al.   THROMBOSIS AND HAEMOSTASIS

Hematologic Effects of Continuous Flow Left Ventricular Assist Devices

(2010) Mark S. Slaughter   Journal of Cardiovascular Translational Research

Characterization of W1745C and S1783A: 2 novel mutations causing defective collagen binding in the A3 domain of von Willebrand factor

(2009) A. F. Riddell et al.   BLOOD

Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men

(2009) B. de Laat et al.   BLOOD

Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13

(2009) J. Chen et al.   BLOOD

Deficiency of von Willebrand factor protects mice from ischemic stroke

(2009) C. Kleinschnitz et al.   BLOOD

Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases associated with oxidative stress

(2009) Stefano Lancellotti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Platelet Adhesion under Flow

(2009) Zaverio M. Ruggeri   MICROCIRCULATION

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: Molecular and Clinical Markers for the Diagnosis and Management of Type 1 VWD (MCMDM-1VWD)

(2008) S. L. Haberichter et al.   BLOOD

Altered thrombus formation in von Willebrand factor-deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa

(2008) I. Marx et al.   BLOOD

Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients

(2008) A. B. Federici et al.   BLOOD

Functional Impairment of Von Willebrand Factor in Hypertrophic Cardiomyopathy

(2008) Thierry Le Tourneau et al.   CIRCULATION

Function of von Willebrand factor in haemostasis and thrombosis

(2008) A. J. REININGER   HAEMOPHILIA

Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions

(2008) Y. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS