Iron and erythropoiesis: a dual relationship

Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-  and Tfr2-  isoforms in different tissues

(2010) A. Roetto et al.   BLOOD

Novel TMPRSS6 mutations associated with iron-refractory iron deficiency anemia (IRIDA)

(2010) Luigia De Falco et al.   HUMAN MUTATION

Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts

(2010) Hong Ye et al.   JOURNAL OF CLINICAL INVESTIGATION

Measurement of serum hepcidin-25 levels as a potential test for diagnosing hemochromatosis and related disorders

(2010) Yoshibumi Kaneko et al.   JOURNAL OF GASTROENTEROLOGY

Binding and uptake of H-ferritin are mediated by human transferrin receptor-1

(2010) Li Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

(2009) L. Silvestri et al.   BLOOD

A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression

(2009) De-Liang Zhang et al.   Cell Metabolism

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

(2009) Duane L Guernsey et al.   NATURE GENETICS

The Microcytic Red Cell and the Anemia of Inflammation

(2009) Siobán B. Keel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I

(2008) H. Tamary et al.   BLOOD

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

(2008) F. Guillem et al.   BLOOD

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

(2008) M. A. Melis et al.   HAEMATOLOGICA

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

(2008) S. B. Keel et al.   SCIENCE

Iron–chelator complexes as iron sources for early developing human erythroid precursors

(2008) Joseph M. Leimberg et al.   Translational Research

Natural History of Recessive Inheritance of DMT1 Mutations

(2007) A. Iolascon et al.   JOURNAL OF PEDIATRICS