Article
Mechanics
H. Jung, I. A. Frigaard
Summary: This study experimentally investigates the effects of inner cylinder rotation on displacement flow of two Newtonian fluids in a horizontal eccentric annulus. The results show that rotation of the inner cylinder changes the flow behavior and can improve the displacement efficiency. This research provides insights for optimizing displacement flows in various applications.
Article
Engineering, Chemical
David Quashie, David Gordon, Paige Nielsen, Shannon Kelley, Sophie Jermyn, Jamel Ali
Summary: We investigate the influence of polymer size, concentration, and viscoelasticity on the propulsion kinematics of achiral microswimmers. We find that the step-out frequency, orientation angle, and propulsion efficiency of magnetically driven swimmers depend on fluid microstructure, viscosity, and viscoelasticity. Moreover, different propulsion efficiencies are observed between larger four-bead swimmers and smaller 3-bead swimmers. Our findings suggest that swimmers in fluids with significant elasticity are more efficiently propelled, while shear thinning behavior enables efficient propulsion in smaller swimmers. These insights will aid in the design and control of microswimmers for complex fluid applications.
Article
Mechanics
P. Pelech, K. Tuma, M. Pavelka, M. Sipka, M. Sykora
Summary: This study investigates the evolution of continuum thermodynamics using the natural configurations theory developed by Rajagopal and Srinivasa, as well as the General Equation for Non-Equilibrium Reversible-Irreversible Coupling (GENERIC) framework. The study demonstrates the compatibility between these seemingly different approaches on a wide range of models, and proposes an interpretation of natural configurations within the GENERIC framework, and vice versa (when possible).
JOURNAL OF NON-NEWTONIAN FLUID MECHANICS
(2022)
Article
Thermodynamics
Jianfei Song, Louis Marcel, Mathieu Specklin, Mickael Lescroart, Jean-Louis Hebert, Smaine Kouidri
Summary: This study aims to evaluate the hemolysis caused by left ventricular assistance devices (LVADs) in the aorta through establishing a numerical model. The results show a relatively low level of hemolysis risks in the aorta, but thrombosis is more prone to occur in the case of severe heart failure condition.
INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW
(2022)
Article
Physics, Condensed Matter
Sushil Dubey, Sukh Veer, R. V. Seshagiri Rao, Chirag Kalelkar, Pramod A. Pullarkat
Summary: This article introduces a versatile device for conducting extensional deformation studies of samples at microscopic scales with simultaneous imaging. The operational features of this device are discussed, and several applications are presented.
JOURNAL OF PHYSICS-CONDENSED MATTER
(2021)
Review
Mechanics
Randy H. Ewoldt, Chaimongkol Saengow
Summary: Taking a step away from Newtonian fluid behavior opens up a wide range of possibilities in terms of non-Newtonian fluid properties. This complexity introduces challenges that need to be addressed. The article explores useful rheological complexity, organizing principles, and design methods to answer questions related to the utility and attainment of non-Newtonian properties.
ANNUAL REVIEW OF FLUID MECHANICS
(2022)
Article
Chemistry, Physical
Marta Stachnik, Monika Sterczynska, Emilia Smarzewska, Anna Ptaszek, Joanna Piepiorka-Stepuk, Oleg Ageev, Marek Jakubowski
Summary: The study on the rheological properties of hot trub in industrial settings revealed that regardless of the raw materials and extract used, all samples exhibited the same rheological properties with different values. The viscosity of hot trub was found to be influenced by both the composition of the raw materials and the temperature.
Article
Engineering, Chemical
Luis Antonio Ramirez-Torres, Luis Medina-Torres, Fausto Calderas, Diola Marina Nunez-Ramirez, Octavio Manero
Summary: The study analyzed the rheological response and computational hydrodynamic behavior to enhance understanding of the bioleaching process in mineral pulps. The results showed that smaller particle size increased the rheological parameters, decreased process time, and indirectly increased bacteria concentration in the medium, leading to higher gel strength. It was also found that a Rushton (top)/Maxflo (bottom) configuration in a dual-impeller bioreactor achieved the best performance, resulting in approximately 9% power savings. Enhanced hydrodynamic conditions were observed at a stirring speed of 400 rpm based on analysis of apparent viscosity maps, velocity fields, and streamlines.
CHEMICAL ENGINEERING & TECHNOLOGY
(2023)
Article
Engineering, Petroleum
Zhuangzhuang Zhang, Zhongwei Huang, Yisu Zhou, Mao Sheng, Bangchen Wu
Summary: Cementation is a crucial process in well drilling, providing safety and isolation for subsequent operations and long-term production. The study focuses on spiral displacement of washout, investigating the characteristics of spiral flow, differences between spiral and nonspiral displacement, and the influence of various parameters. Spiral flow proves to be advantageous for cementing, with different accumulation patterns compared to axis flow.
Article
Mechanics
Miguel A. Jimenez-Urias, Thomas W. N. Haine
Summary: In this study, we use a linear and analytical eigenfunction approach to compute solutions to the two-dimensional advection-diffusion equation. We uncover the specific role of the non-self-adjointness of the linear operator in the solution behavior and highlight its multiscale nature.
JOURNAL OF FLUID MECHANICS
(2023)
Article
Engineering, Biomedical
Sascha Ranftl, Thomas Stephan Mueller, Ursula Windberger, Guenter Brenn, Wolfgang von der Linden
Summary: Computational hemodynamics has gained attention recently, but the credibility of patient-specific simulations is often in doubt due to questionable model assumptions. In this study, the impact of blood rheological models on wall shear stress uncertainties in aortic hemodynamics was investigated using Bayesian Probability Theory. The findings indicate that non-Newtonian models provide more realistic uncertainties compared to Newtonian models, and a more precise determination of person-specific blood rheological properties is necessary for accurate person-specific simulations.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2023)
Review
Physics, Condensed Matter
Christopher Ness, Ryohei Seto, Romain Mari
Summary: This article reviews the current understanding of the relationship between particle-scale physics and macroscopic rheology, and demonstrates how this perspective opens new avenues for the development of continuum models for dense suspensions.
ANNUAL REVIEW OF CONDENSED MATTER PHYSICS
(2022)
Review
Mechanics
S. Afiqah Wajihah, D. S. Sankar
Summary: This paper summarizes the research field of hemodynamics, including the flow characteristics of blood, the geometry of blood vessels, and the behavior of blood under normal and abnormal flow conditions. By discussing mathematical modeling and solution methods, the influence of these parameters on physiologically important flow quantities is understood. The study found that the impact of resistance on blood flow varies in different states, such as healthy, anemic, and diabetic, and severe arterial stenosis can result in inadequate blood supply to organs, leading to patient death. It is hoped that the results of this study can help predict blood behavior and flow in stenotic arteries, and provide valuable physiological information for treating cardiovascular diseases.
ARCHIVE OF APPLIED MECHANICS
(2023)
Article
Chemistry, Analytical
Jiaxuan Zheng, Jialu Wang, Yongjun Jian
Summary: In this article, the performance of electro-osmotic thrusters filled with non-Newtonian power-law fluids in a microchannel was theoretically investigated. Results show that the performance curves depend strongly on the flow behavior index and the electrokinetic width. It is found that non-Newtonian pseudoplastic fluids are the most suitable propellant solvents in micro electro-osmotic thrusters.
Article
Chemistry, Analytical
Georgia Kontaxi, Yorgos G. Stergiou, Aikaterini A. Mouza
Summary: This study compares the characteristics of bubbles formed in non-Newtonian and Newtonian fluids, finding that the final diameter of the bubbles is influenced by the gas flow rate and liquid phase viscosity. Simulation results indicate that high shear rates around bubbles in non-Newtonian fluids lead to the viscosity approaching its asymptotic value.
Article
Chemistry, Medicinal
Catia Correia, Evandro Tavares, Carlos Lopes, Joana G. Silva, Andreia Duarte, Vitor Geraldes, Miguel A. Rodrigues, Eduardo P. Melo
JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Chemistry, Medicinal
Vitor Geraldes, Diana C. Gomes, Pedro Rego, Deborah Fegley, Miguel A. Rodrigues
JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Thermodynamics
Joana M. Pinheiro, Sergio Salustio, Vitor Geraldes, Anabela A. Valente, Carlos M. Silva
APPLIED THERMAL ENGINEERING
(2020)
Article
Pharmacology & Pharmacy
Andreia Duarte, Pedro Rego, Aida Ferreira, Paulo Dias, Vitor Geraldes, Miguel A. Rodrigues
Article
Chemistry, Multidisciplinary
Oliver Bluemel, Jakob W. Buecheler, Miguel A. Rodrigues, Vitor Geraldes, Georg Hoelzl, Karoline Bechtold-Peters, Wolfgang Friess
PHARMACEUTICAL RESEARCH
(2020)
Article
Pharmacology & Pharmacy
Tiago Porfirio, Francisco J. Galindo-Rosales, Laura Campo-Deano, Joao Vicente, Viriato Semiao
Summary: The study provides rheological characterization of commonly used polymers and solvents for formulating amorphous solid dispersions using spray drying. Different polymers exhibit distinct rheological behaviors, which can aid in understanding spray drying processes.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Chemistry, Physical
Miguel A. Rodrigues, Pedro Rego, Vitor Geraldes, Lauren E. Connor, Iain D. H. Oswald, Michael Sztucki, Evgenyi Shalaev
Summary: The study shows that mannitol crystallizes during cooling at a lower rate than a critical value, or during subsequent heating if the cooling rate is higher. A temperature-composition phase diagram is constructed to illustrate the phase equilibria involving various crystalline forms. The findings provide insights for improving formulations and manufacturing processes in pharmaceutical and biopharmaceutical industries.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Engineering, Chemical
Diana C. Gomes, Vitor Geraldes, Deborah Fegley, Miguel A. Rodrigues
Summary: The study measured the mutual diffusion of different proteins in cold concentration gradients, showing that the SE model provided a reasonable description for most cases. However, in some cases, the diffusion rate of Ova was higher than predicted and exhibited nonlinear temperature dependence.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Construction & Building Technology
Nuno Serra, Viriato Semiao
Summary: Built environments are major energy consumers, and tools supporting their efficient design and guaranteeing comfort and air quality are crucial. Computational Fluid Dynamics (CFD) procedures have been widely used for predicting built environment flows with the optimization of pressure-velocity coupling being a possible strategy to reduce computational time.
BUILDING AND ENVIRONMENT
(2021)
Article
Thermodynamics
Duarte Pereira de Araujo Coutinho, Jorge Augusto Maciel Milhomem Rodrigues, Aires Jose Pinto dos Santos, Viriato Sergio de Almeida Semiao
Summary: The study introduces a thermoeconomic model for a distributed-scale hybrid solar-thermal power plant, which utilizes a genetic algorithm for multi-objective optimization to obtain a set of Pareto-optimal designs. The optimized designs significantly reduce levelized electricity costs, improve system efficiencies, and increase solar shares.
ENERGY CONVERSION AND MANAGEMENT
(2021)
Article
Chemistry, Medicinal
Oliver Bluemel, A. Miguel Rodrigues, W. Jakob Buecheler, Vitor Geraldes, Georg Hoelzl, Astrid Hauptmann, Karoline Bechtold-Peters, Wolfgang Friess
Summary: This article describes two novel devices that mimic the stress in large containers during freezing and thawing of monoclonal antibodies. The devices were able to predict aggregation in the large containers and provide characterization of protein sensitivity with smaller volumes. One device underestimated soluble aggregate formation while the other device slightly overestimated it. These devices offer a more representative approach compared to simply using smaller bottles.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mario Rito Pereira, Goncalo Silva, Viriato Semiao, Vania Silverio, Jorge N. R. Martins, Paula Pascoal-Faria, Nuno Alves, Juliana R. Dias, Antonio Ginjeira
Summary: This study experimentally validated a computational fluid dynamics (CFD) model by using micro-particle image velocimetry (micro-PIV) measurements of the irrigation flow velocity field developed in confluent canals. The results showed a good agreement between the micro-PIV experimental and CFD predicted data, indicating that laminar CFD modeling is reliable for predicting flow in similar domains.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mario Rito Pereira, Goncalo Silva, Viriato Semiao, Jorge N. R. Martins, Vania Silverio, Paula Pascoal-Faria, Isabel Duarte, Nuno Alves, Antonio Ginjeira
Summary: This study assesses the influence of root canal preparation, irrigation needle design, and its placement depth on the irrigation flow of confluent canals. The results show that apical penetration and renewal of the irrigant are most efficiently achieved with the use of a 30G open-ended needle and a 30/.07v preparation.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Pharmacology & Pharmacy
Miguel A. Rodrigues, Andreia Duarte, Vitor Geraldes, Jonathan S. Kingsbury, Patke Sanket, Vasco Filipe, Mostafa Nakach, Jean -Rene Authelin
Summary: Assessment of cold stability is crucial for the manufacture and commercialization of biotherapeutics. However, the conventional approach of estimating storage stability often underestimates protein aggregation. In this study, a novel method of measuring aggregation rates using isochoric cooling was used to prevent freezing, and mathematical models were employed to analyze the effects of hot and cold denaturation on aggregation. The results provided valuable insights into the aggregation rates at refrigeration temperature and could be achieved in a relatively short timeframe using standard characterization techniques.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Proceedings Paper
Computer Science, Artificial Intelligence
Tiago Eusebio, Monica Faria, Viriato Semiao, Maria Norberta de Pinho
XV MEDITERRANEAN CONFERENCE ON MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING - MEDICON 2019
(2020)
Article
Thermodynamics
Navid Freidoonimehr, Azadeh Jafari, Maziar Arjomandi
Summary: In this study, a high-fidelity flow visualisation technique is used to investigate the resemblance between a turbulent boundary layer generated by different tripping devices in a lab environment and a naturally developed canonical turbulent boundary layer. The study finds that the blockage created by trips is the main factor affecting the turbulence statistics at a certain downstream distance.
INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW
(2024)
Article
Thermodynamics
Yuning Wang, Alberto Solera-Rico, Carlos Sanmiguel Vila, Ricardo Vinuesa
Summary: This study proposes a method that combines 6-VAEs for modal decomposition and transformer neural networks for temporal-dynamics prediction in the latent space to develop reduced-order models (ROMs) for turbulent flows. The method achieves high reconstruction accuracy and accurate prediction of temporal dynamics.
INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW
(2024)
Article
Thermodynamics
L. Laguarda, S. Hickel, F. F. J. Schrijer, B. W. van Oudheusden
Summary: Wall-resolved large-eddy simulations were used to investigate the Reynolds number effects in supersonic turbulent boundary layers at Mach 2.0. The study covered a wide range of friction Reynolds numbers and identified trends in various statistics and scaling laws. The size and topology of turbulent structures in the boundary layer were examined, with a focus on the outer-layer motions at high Reynolds numbers. The study also assessed the influence of outer-layer structures on near-wall turbulence and the sensitivity of uniform momentum regions to compressibility.
INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW
(2024)
Article
Thermodynamics
A. Doehring, T. Kaller, S. J. Schmidt, N. A. Adams
Summary: In this study, well-resolved large-eddy simulations were used to investigate turbulent duct flows with a square cross section. The influence of a modified wall shear stress on the secondary flow was analyzed by artificially modifying the wall shear stress at one of the four walls. The results showed that the modification led to an asymmetrical distribution of the secondary flow source terms, affecting the momentum distribution. Furthermore, the anisotropy of the Reynolds stress tensor, which induces the secondary flow vortices, was significantly affected by the wall shear stress modulation.
INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW
(2024)
